Protein Alignment peng and Pum3l1

DIOPT Version :10

• Sequence 1: NP_523429.1
• Gene: peng / 33112
• FlyBaseID: FBgn0015527
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_038956171.1
• Gene: Pum3l1 / 294066
• RGDID: 1308750
• Length: 647
• Species: Rattus norvegicus
• Alignment Length: 741
• Identity: 194/741 - (26%)
• Similarity: 327/741 - (44%)
• Gaps: 152/741 - (20%)

  Fly    16 ASPLKAHESSGKRANGQKFKPGGAGGARKFDKFGGGAGKSFVKPGAGGAKKFDKSGPGGFK---- 76
            |.|.||.:..|.:...:.|:.|.                  .|||..|.|:| |:.|.|.|
  Rat    34 AFPRKAAKEGGPKVTSKNFEKGA------------------TKPGKKGVKQF-KNKPQGGKGPKD 79

  Fly    77 KFDKSGATGDKRLGGNKFRGKPQTQPQAPAE---GEKQDWNKFKKEKKDLKLKRK-SAKDTYEIS 137
            ||.|:          |||..|.:.||...::   .:|..|:.|||:||:||..|: |.|..|::.
  Rat    80 KFQKA----------NKFNKKRKFQPDGKSDESAAKKPKWDDFKKKKKELKQNRQLSDKTNYDVV 134

  Fly   138 KEANQIHEKLR---CRRTENKDKLVEQIYKVLNVGDTISKVVKAHDTARVIQSMLKYASPALRAE 199
            ..|..|.|.||   |.: |.:.||:..:.|::.  ..|..:..|||:.||||.:::|.|...|..
  Rat   135 VRAKHIWESLRRKDCDK-EKRVKLMSDLQKLIQ--GKIKTIAFAHDSTRVIQCLIQYGSEEQRKW 196

  Fly   200 ISEKLLPFTVEMCQSKYAQFCVQRMLKYGAPATKAKLVDSLYGHIVRLAGHSIGSGLLDSMY-QS 263
            ..|:|....||:.::||::..|::.|.||:....|:::.|..||:.::..||..|.:::..| ..
  Rat   197 AFEELQGDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHSEASAIVEYAYNDK 261

  Fly   264 ATPNQRIYMRQEFYGDLYRKAKDSNVKTLSDTYKEATNMKASILGSVKANLDHVANKQ-LVDSAL 327
            |...||..:.:|.||:.::..|.::..||....:........||..:|..|..:|.|: ::..:|
  Rat   262 AILEQRNMLTEELYGNTFQLYKSADHPTLEKVLEVQPGKLELILDEMKQILTPMAQKEAVIKHSL 326

  Fly   328 VHAVMLEYLRACDEDEEKL-EETVTAFAALVPHMLSTKEGSEAAVICFYKSTPKNRRAIIKNIKE 391
            ||.|.|::....   ..|| .|.:.|....|.::..|.:|:..|:.|.:..|||:|:.|:|.:|.
  Rat   327 VHKVFLDFFTYA---PPKLRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKT 388

  Fly   392 HLLKIANHEHGHVFLISLLNALDDTKATKKAIYDHLHGDLKALMSSPYGRRVIQWLVAPGDTTCF 456
            ::.||||.::.|:.|::..:.:||||..|:.|...:...|.::::..|||:|:.:|::|.::...
  Rat   389 YVEKIANGQYSHLVLLAAFDCIDDTKLVKQIIISEVISSLPSIVNDKYGRKVLLYLLSPRNSAHL 453

  Fly   457 HPEFIRTVE--EGLAFGKKEKELRRKEILEQIEAPIAQSIAEDAAFWLSNSHIGLVTGDILNHIQ 519
            .||.|:.::  :|.|..||:..:||:|:||.|...                        :|:::|
  Rat   454 VPEIIQLLQKGDGNAHSKKDTAIRRRELLESISPA------------------------LLSYLQ 494

  Fly   520 GESYEKAASALAQVVVQPEWRISADAAGPQPQDKKKPHNDVEAIIAQATKQRRKLLYVESSSDDE 584
            |.:.|........|:|..                         |:..||
  Rat   495 GHTREVVLDKSVCVLVSD-------------------------ILGSAT---------------- 518

  Fly   585 DEDEDEDEESDDEGDEKEQKEAAADDAEPKVKKAKKEPKKPKAKEEEPAAPLVSGIEEAGMHIVL 649
                         ||.:...:|.|..|..::....|:.:...|  |.||.           |:||
  Rat   519 -------------GDAQPAMDAIAGLAAEELYPGGKDGELHIA--EHPAG-----------HLVL 557

  Fly   650 KKILKNDGK-----REGTPFSQQLLQNLSSDVLKAWLGVNRACFVLLKLVEECPALLDDCKKAIA 709
            |.:::.|.|     :||. |::.|::......||:|..:||...||..|::.|..  |...|..|
  Rat   558 KWLIEQDKKIKENGKEGC-FAKTLVECFGVKNLKSWASINRGAIVLSSLLQSCDQ--DVVNKVKA 619

  Fly   710 AERSLSQILADRK--TPGAKLLAAKL 733
            ..::|...|...|  :.|.:.|..||
  Rat   620 GLKTLIPTLEKTKSTSKGIQTLLEKL 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
peng	NP_523429.1	Pumilio	<183..>254	CDD:480718	23/70 (33%)
		Pumilio	438..>537	CDD:480718	25/100 (25%)
Pum3l1	XP_038956171.1	Pumilio	181..441	CDD:480718	76/262 (29%)
		CPL	433..570	CDD:462370	44/227 (19%)