DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fliI and capg

DIOPT Version :9

Sequence 1:NP_525097.1 Gene:fliI / 33110 FlyBaseID:FBgn0000709 Length:1256 Species:Drosophila melanogaster
Sequence 2:NP_001011294.1 Gene:capg / 496747 XenbaseID:XB-GENE-5811032 Length:346 Species:Xenopus tropicalis


Alignment Length:340 Identity:100/340 - (29%)
Similarity:166/340 - (48%) Gaps:22/340 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   498 GLTIWEIENFLPNKIEEVVHGKFYEGDCYIVLKTKFDDLGLLDWEIFFWIGNEATLDKRACAAIH 562
            ||.::.||......:....||.|:.||.|:::....:..     .||.|.|::.::|:||..||:
 Frog    20 GLHVFRIEKMKLISLPSESHGVFHSGDTYLLVFNSSESN-----SIFVWNGSDTSVDERAAGAIY 79

  Fly   563 AVNLRNFLGARCRTVREEQGDESEQFLSLFETEVIYIEGGRTATGFYTIEEMIHITRLYLVHAYG 627
            :..|...|..:....:|.||:||.:|:|||...|.|::|| .::||:...:.......:|.|..|
 Frog    80 SFQLHKHLREKPVQNQETQGNESAEFMSLFPLGVTYLDGG
-VSSGFHRASQDTVAPTYHLYHVRG 143

  Fly   628 ATIHLEPVAPAIT-----SLDPRHAFVLDLGTHIYIWMGERSKNTLNSKARLMAEKISKTERKNK 687
            .    :.:..|.|     |.:....|:||.|..||:|.|.:|.....::||.:|.:|..:||:..
 Frog   144 R----KQIRAAETELKWESFNKGDCFILDTGKSIYVWSGSQSNILERNRARDLAYQIRDSERRGA 204

  Fly   688 CEIQLERQGEESAEFWQGLGMTSEE-ADA-AEPPKEHVPEDYQPVQPRLYQVQLGMGYLELPQVE 750
            .::::.::|||..|..:.||...|. .|| ||..||  .::.......||:|....|.:::..| 
 Frog   205 AKVEIIQEGEEPEEMIKILG
KCPESLRDANAEDDKE--ADERHTKGATLYKVSNASGQMQVTHV- 266

  Fly   751 LPEQKLCH-TLLNSKHVYILDCYTDLFVWFGKKSTRLVRAAAVKLSRELFNMMDRPDYALVMRVP 814
             .:..|.| ..|.|...:||||...::||.||::.:..:..::|.:.|..::|.......|..|.
 Frog   267 -GDGALFHKEQLISDDCFILDCVGKIYVWKGKRANKEEQDCSLKTANEFLSLMRYSPTTQVQVVS 330

  Fly   815 EGNEMQIFRTKFAGW 829
            ||||..:||..|..|
 Frog   331 EGNESPLFRQFFRNW 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fliINP_525097.1 leucine-rich repeat 7..30 CDD:275380
leucine-rich repeat 31..53 CDD:275380
LRR_8 53..112 CDD:290566
leucine-rich repeat 54..76 CDD:275380
LRR_RI 70..304 CDD:238064
leucine-rich repeat 77..101 CDD:275380
LRR_8 101..159 CDD:290566
leucine-rich repeat 102..124 CDD:275380
leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 149..171 CDD:275380
LRR_8 152..231 CDD:290566
leucine-rich repeat 172..195 CDD:275380
leucine-rich repeat 196..220 CDD:275380
leucine-rich repeat 221..243 CDD:275380
LRR_8 243..300 CDD:290566
leucine-rich repeat 244..266 CDD:275380
leucine-rich repeat 267..289 CDD:275380
leucine-rich repeat 290..314 CDD:275380
LRR_8 315..370 CDD:290566
leucine-rich repeat 315..335 CDD:275380
leucine-rich repeat 338..360 CDD:275378
gelsolin_S1_like 491..602 CDD:200446 32/103 (31%)
gelsolin_like 618..706 CDD:200436 25/92 (27%)
gelsolin_S3_like 729..828 CDD:200448 29/99 (29%)
gelsolin_like 920..1015 CDD:200436
gelsolin_S5_like 1037..1141 CDD:200444
gelsolin_S6_like 1151..1250 CDD:200447
capgNP_001011294.1 ADF_gelsolin 18..119 CDD:387665 32/103 (31%)
gelsolin_S2_like 136..224 CDD:200445 25/91 (27%)
gelsolin_S3_like 249..344 CDD:200448 29/96 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1376537at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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