Protein Alignment fliI and Lap1

DIOPT Version :10

• Sequence 1: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_611007.1
• Gene: Lap1 / 36670
• FlyBaseID: FBgn0033984
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 145/498 - (29%)
• Similarity: 215/498 - (43%)
• Gaps: 80/498 - (16%)

  Fly     6 FVRGVDFTKNDFSAT----FPSSMRQMSRVQWLTLDRTQLAEIPEELGHLQKLEHLSLNHNRLEK 66
            |.|.....|.|:|.|    ||...:....::.|.|..|:|..:|.:|.:.|.|..|.:|.|.||.
  Fly    13 FKREEVIDKLDYSNTPLTDFPEVWQHERTLEELYLSTTRLQALPPQLFYCQGLRVLHVNSNNLES 77

  Fly    67 IFGELTELSCLRSLDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLS 131
            |...:..|..|:.|||..|.:.|  :|.|:...:.||.||||.|.|:.:|:.:....:|..|.|:
  Fly    78 IPQAIGSLRQLQHLDLNRNLIVN--VPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLN 140

  Fly   132 NNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDLSHNPL--------ELFQLR 188
            ...:|.:|.. |..|.:|..|:|..|.|.|||....|||||:.||:..|..        ||..||
  Fly   141 ETYLEFLPAN-FGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLR 204

  Fly   189 QL--------------PSLQSLEVLKMSGTQRTLLNFPTSIDSLANLCELDLSHNSLPKLPDCVY 239
            :|              ..|:.|:..:.:|  ..|...|:.:.:..|:..|.:..|||...|..|.
  Fly   205 ELWIDFNQIRRVSANIGKLRDLQHFEANG--NLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVG 267

  Fly   240 NVVTLVRLNLSDNELTELTAGVELWQRLESLNLSRNQLVALPAALCKLPKLRRLLVNDNKLNFEG 304
            .:.:||......|.||||...:...::||.|.||.|:|:.||:.:..|..||.|..:||:|  ..
  Fly   268 MLKSLVTFKCESNGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQL--RQ 330

  Fly   305 IPSGIGKLGALEVFSAANNLLEMVPEGLCRCGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRNN 369
            :|..:.....|.|.|.|||.|..:|:.:.....:|.||:..|.:..||.::..|..|..:.|.:|
  Fly   331 LPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDN 395

  Fly   370 -PELVMPPKPSEASKATSL----------------------EFYNIDFSLQTQ------------ 399
             .:.::|.:..:||..|.|                      |.|...::.|.|
  Fly   396 QSQPLVPLQYLDASTKTQLTCFMLPQVTFKMNSIQAQQQAQEQYEFVYANQQQPHASPSRRICFA 460

  Fly   400 -----LRLAGAAVPPSMPS------SATPKDSTARKIRLRRGP 431
                 |..|.|...|:.||      :.|| |..|..:||.|.|
  Fly   461 EEATILSNAKAQPAPNYPSFVAAPPTPTP-DQMAGSVRLMRSP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380	7/26 (27%)
		leucine-rich repeat	31..53	CDD:275380	6/21 (29%)
		LRR	33..405	CDD:443914	125/433 (29%)
		leucine-rich repeat	54..76	CDD:275380	8/21 (38%)
		leucine-rich repeat	77..101	CDD:275380	8/23 (35%)
		leucine-rich repeat	102..124	CDD:275380	9/21 (43%)
		leucine-rich repeat	125..148	CDD:275380	7/22 (32%)
		leucine-rich repeat	149..171	CDD:275380	10/21 (48%)
		leucine-rich repeat	172..195	CDD:275380	10/44 (23%)
		leucine-rich repeat	196..220	CDD:275380	4/23 (17%)
		leucine-rich repeat	221..243	CDD:275380	6/21 (29%)
		leucine-rich repeat	244..266	CDD:275380	7/21 (33%)
		leucine-rich repeat	267..289	CDD:275380	10/21 (48%)
		leucine-rich repeat	290..314	CDD:275380	7/23 (30%)
		leucine-rich repeat	315..335	CDD:275380	8/19 (42%)
		leucine-rich repeat	338..360	CDD:275378	7/21 (33%)
		gelsolin_S1_like	491..602	CDD:200446
		gelsolin_like	618..706	CDD:200436
		gelsolin_S3_like	729..828	CDD:200448
		gelsolin_like	920..1015	CDD:200436
		gelsolin_S5_like	1037..1141	CDD:200444
		gelsolin_S6_like	1151..1250	CDD:200447
Lap1	NP_611007.1	LRR	12..407	CDD:443914	123/400 (31%)
		leucine-rich repeat	21..41	CDD:275380	6/19 (32%)
		leucine-rich repeat	42..64	CDD:275380	6/21 (29%)
		leucine-rich repeat	65..87	CDD:275380	8/21 (38%)
		leucine-rich repeat	88..110	CDD:275380	8/23 (35%)
		leucine-rich repeat	111..133	CDD:275380	9/21 (43%)
		leucine-rich repeat	134..156	CDD:275380	7/22 (32%)
		leucine-rich repeat	157..179	CDD:275380	10/21 (48%)
		leucine-rich repeat	180..202	CDD:275380	6/21 (29%)
		leucine-rich repeat	203..225	CDD:275380	4/21 (19%)
		leucine-rich repeat	226..248	CDD:275380	4/23 (17%)
		leucine-rich repeat	272..294	CDD:275380	7/21 (33%)
		leucine-rich repeat	295..317	CDD:275380	10/21 (48%)
		leucine-rich repeat	318..340	CDD:275380	7/23 (30%)
		leucine-rich repeat	364..386	CDD:275380	7/21 (33%)
		PDZ_canonical	778..846	CDD:467153