Protein Alignment fliI and scinla

DIOPT Version :10

• Sequence 1: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_835232.2
• Gene: scinla / 323285
• ZFINID: ZDB-GENE-030131-2005
• Length: 720
• Species: Danio rerio
• Alignment Length: 796
• Identity: 220/796 - (27%)
• Similarity: 334/796 - (41%)
• Gaps: 122/796 - (15%)

  Fly   485 YSKFFEKDDGQLPGLTIWEIENFLPNKIEEVVHGKFYEGDCYIVLKTKFDDLGLLDWEIFFWIGN 549
            :.|.|: :.|:.|||.||.||......:.:.:||.|:.||.|:||.|.    ....:.:..|:||
Zfish     3 FHKEFQ-NAGKEPGLQIWRIEKMDLKLVPKQLHGNFFTGDAYVVLFTS----PAPSYNVHMWLGN 62

  Fly   550 EATLDKRACAAIHAVNLRNFLGARCRTVREEQGDESEQFLSLFETEVIYIEGGRTATGF-YTIEE 613
            |.:.|:...|||.|:.|.:.||......||.|.:||..||..|:|.:.|.:|| .::|| :.:..
Zfish    63 ECSQDESGAAAIFAMQLDDHLGGAPVQYREVQNNESVTFLGYFKTGIKYKQGG-VSSGFNHVVSN 126

  Fly   614 MIHITRLYLVHAYG-ATIHLEPVAPAITSLDPRHAFVLDLGTHIYIWMGERSKNTLNSKARLMAE 677
            .::..|  ::|..| ..|....|..:..|.:....|:||||..||.|.|.:.......||..::.
Zfish   127 EMNTKR--VLHIKGRRAIRATEVNMSWASFNHGDCFILDLGKDIYQWCGSKCNRFERLKASEVSI 189

  Fly   678 KISKTERKNKCEIQLERQGEESAEFWQGLGMTSEEADAAEPPKEHVPE---DYQPV------QPR 733
            .|...||..:..:.:...|.|...|...||           ||..:||   |.:..      :..
Zfish   190 GIRDNERNGRATLHIVEDGSEPDVFSNTLG-----------PKPSIPEGSPDDETTDRNNQKKAS 243

  Fly   734 LYQVQLGMGYLELPQVELPEQKLCHTLLNSKHVYILDCYTD--LFVWFGKKSTRLVRAAAVKLSR 796
            |:.|....|.::..:|: ........|||....||||...|  :|||.|.::....|.:|:|::.
Zfish   244 LHMVSDAAGSMKTSEVK-QNSPFKQELLNPSDCYILDNGLDSKIFVWKGPRANTEERKSAMKVAE 307

  Fly   797 ELFNMMDRPDYALVMRVPEGNEMQIFRTKFAGWDEVMAVDFTRTAKSVAKTGANLTQWARQQETR 861
            :.....:.|....:..:|.|.|..:|:..|:.|.:.........|.|:.:.       ||..:..
Zfish   308 QFIKEKNYPKNTQIQVMPGGGETTLFKQFFSNWKDKDQSTGPGQAYSIGRI-------ARVSQVP 365

  Fly   862 TDLAAL----FMPRQSAMPLAEAEQLEEEWNYDLEMMEAFVLENKKFVRLPEEELGRFYTGECYV 922
            .|.::|    .|..|..| :.:.....:.|.          :|....|.:.....|:|:.|:||:
Zfish   366 FDASSLHSNKVMAAQHGM-VDDGSGKVQVWR----------VEGNDRVPVDPSSFGQFFGGDCYL 419

  Fly   923 FLCRYCIPIEEPENGSEDGANPAADVSKSSANNQPEDEIQCVVYFWQGRNAGNMGWLTFTFTLQK 987
            .|..|.       ||..:                     |.::|.|||............|...|
Zfish   420 ILYTYL-------NGGRE---------------------QHIIYTWQGLKCTQDELTASAFLTVK 456

  Fly   988 KFKAMFGEELEVVRIFQQQENLKFMSHFKRK-FIIHTGKRKDKAHTAKGKSPV---EFFHLRSNG 1048
            ...:|.|..:: ||:.|.||....||.||.| .|||.|....|.    |:|.|   ..||:|.:
Zfish   457 LDDSMGGAPVQ-VRVTQGQEPAHLMSLFKGKPMIIHLGGTSRKG----GQSRVGTTRLFHIRQS- 515

  Fly  1049 GALTTRLIQINPDAVHLNSTFCYILHVPFETEDDSQSGIVYVWIGSKACNEE---AKLVQDIAEQ 1110
            ....||.:::.|.|..||:...::|..|        .| :::|.|..|..||   ||.|..|...
Zfish   516 STRATRAVEVEPCASKLNTNDVFVLKFP--------EG-MFLWKGVGASEEEIAAAKYVCSILGG 571

  Fly  1111 MFNSPWVSLQILNEGDEPENFFWVALGGRKPYDTD---AEYMNYTRLFRCSNERGYYTVAEKCAD 1172
                   |...::||.||. .||.:|||:|.|.|.   .:.:...|||.|||:.|.....|...|
Zfish   572 -------SATEISEGKEPA-AFWSSLGGKKDYQTSKNLQKTVKLPRLFGCSNKTGRLIAEEVPGD 628

  Fly  1173 FCQDDLADDDIMILDNGEHVFLWMGPRCSEVEVKL-AYKSAQVYIQHMRIKQPERPRKLFLTMKN 1236
            ..|.|||.||:|:||..:.:|||:| ..:.||.|: :.|.|:.|:.....|:...|   .:|:|.
Zfish   629 LTQSDLATDDVMLLDTWDQIFLWIG-NDANVEEKIGSAKIAKDYVDSDPSKRQGIP---IITIKQ 689

  Fly  1237 K-ESRRFTKCFHGWSA 1251
            . |...||..|..|.:
Zfish   690 GFEPPSFTGWFQAWDS 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380
		leucine-rich repeat	31..53	CDD:275380
		LRR	33..405	CDD:443914
		leucine-rich repeat	54..76	CDD:275380
		leucine-rich repeat	77..101	CDD:275380
		leucine-rich repeat	102..124	CDD:275380
		leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	149..171	CDD:275380
		leucine-rich repeat	172..195	CDD:275380
		leucine-rich repeat	196..220	CDD:275380
		leucine-rich repeat	221..243	CDD:275380
		leucine-rich repeat	244..266	CDD:275380
		leucine-rich repeat	267..289	CDD:275380
		leucine-rich repeat	290..314	CDD:275380
		leucine-rich repeat	315..335	CDD:275380
		leucine-rich repeat	338..360	CDD:275378
		gelsolin_S1_like	491..602	CDD:200446	39/110 (35%)
		gelsolin_like	618..706	CDD:200436	23/88 (26%)
		gelsolin_S3_like	729..828	CDD:200448	25/106 (24%)
		gelsolin_like	920..1015	CDD:200436	22/94 (23%)
		gelsolin_S5_like	1037..1141	CDD:200444	33/109 (30%)
		gelsolin_S6_like	1151..1250	CDD:200447	36/100 (36%)
scinla	NP_835232.2	gelsolin_S1_like	7..115	CDD:200446	40/112 (36%)
		gelsolin_S2_like	131..212	CDD:200445	22/82 (27%)
		gelsolin_S3_like	239..339	CDD:200448	25/100 (25%)
		gelsolin_S4_like	383..483	CDD:200449	29/139 (21%)
		gelsolin_S5_like	506..594	CDD:200444	31/105 (30%)
		gelsolin_S6_like	608..704	CDD:200447	36/99 (36%)