Protein Alignment fliI and qua

DIOPT Version :10

• Sequence 1: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_061510394.1
• Gene: qua / 1280190
• VectorBaseID: AGAMI1_007991
• Length: 877
• Species: Anopheles gambiae
• Alignment Length: 856
• Identity: 182/856 - (21%)
• Similarity: 316/856 - (36%)
• Gaps: 172/856 - (20%)

  Fly   469 LKPKRWDESLEKPQLDYSKF---FEKDDGQLPGLTIWEIENFLPNKIEEVVHGKFYEGDCYIVLK 530
            :..|.:|:  ::|..:..|.   |.|...:..|..:|.|:......:.:..:|.||:...|::..
Mosquito     6 INQKDYDQ--KRPVYEDIKIDTAFRKISPRSIGFHVWRIQQDHVETLPKEQYGTFYDECAYVIYA 68

  Fly   531 TKFDDL---------------GLLDWEIFFWIGNEATLDKRACAAIHAVNLRNFLGARCRTVREE 580
            ......               ..::..|.||:|.....::...||...:.|...|..:....||.
Mosquito    69 ASLTGTTCDKSTISREIKAPGAAIERNIHFWLGANIPAERSKSAAYKIIELDLHLDHKTTQFRES 133

  Fly   581 QGDESEQFLSLFETEVIYIEGGRTATGFYTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPR 645
            ||:|..:|||.|:.:.|.:..|..|:...|      ..|||.:........::....:....:..
Mosquito   134 QGNEGIRFLSYFKDDGILVHSGSDASSTPT------NPRLYQISGTAPQRCVQQKTISWQCFNSG 192

  Fly   646 HAFVLDLGTHIYIWMGERSKNTLNSKARLMAEKISKTERKNKCEIQLERQGEESA------EFWQ 704
            ...:|...:.:::|:|..:.:........|.|::.  ::....|:.:...|.|.:      |.|.
Mosquito   193 QVMILQTASIVFVWIGRSTGSVERIFGIRMGERLK--QQHAIAELAIVDDGYEQSMSIARKEVWN 255

  Fly   705 G-LGMTSEEADAAEPPKEHVPEDYQPVQP-------RLYQVQL--GMGYLELPQVELPEQKLCHT 759
            | |.:.          |..|..  .|:.|       :||....  |:..:||.:....:|.   .
Mosquito   256 GYLNLA----------KRFVKP--MPLTPTVAERLLKLYHCDTVNGVFRVELVKTGALDQA---D 305

  Fly   760 LLNSKHVYILDCYTD-LFVWFGKKSTRLVRAAAVKLSRELFNMMDRPDYALVMRVPEGNEMQIFR 823
            |.....:||:|.:.. :::|.|:.|.:..||.|::..|........|....|.||.:|.|...|.
Mosquito   306 LYGRDSIYIVDYFPQAIWIWIGRSSHKQNRAEAMRHVRGYVIKKGYPAGTPVARVIDGLEPAEFV 370

  Fly   824 TKFAGWDEVMAVDFT-RTAKSVAKTGANLTQWARQQETRTDLAALFMPRQSAMPLAEAEQLEEEW 887
            :.|..|   .:.|.. .|.|.:::....||...|             ||     :|...||.::.
Mosquito   371 SLFPAW---TSADINGNTVKGLSEKFDALTLIQR-------------PR-----MAAKIQLMDDG 414

  Fly   888 NYDLEMMEAFVLENKKFVRLPEEELGRFYTGECYVFLCRYCIPIEEPENGSEDGANPAADVSKSS 952
            :.|:.:.:..:.|.|:   :|.:....||:|.||                   ..:.....|..:
Mosquito   415 SGDMTVYQIGIDEVKE---IPNKYAKTFYSGNCY-------------------AVHYEVACSTEN 457

  Fly   953 ANNQPEDEIQCVVYFWQGRNAGNMGWLTFTFTLQKKFKAMFGEELE----VVRIFQQQENLKFMS 1013
            ||....:.|:.|||.|.|.||.     ....|:.:.|.|...|.|:    .|||.:..|...|:.
Mosquito   458 ANGSLPNSIRNVVYLWCGLNAP-----PEHRTIGEAFLAELCEHLKKNVVQVRIAEGMEPPHFLQ 517

  Fly  1014 HFKRKFIIHTGKRKDKAHTAKG------KSPVEFFHLRSNGGA-LTTRLIQINPDAVHLNSTFCY 1071
            .||...|:...  :|.:....|      :.|..|. |:..|.| .|.:.:|::...::.... ||
Mosquito   518 IFKGSLIVLNA--QDPSLEQAGAVVNIRQYPTSFV-LKVVGNATYTCKAVQVSSKTLYYPED-CY 578

  Fly  1072 ILHVPFETEDDSQSGIVYVWIGSKACNEEAKLVQDIAEQMFNSPWVSLQILNEGDEPENFFWVAL 1136
            ||..|     |::   |::|.|..:..:..::.:.||.|:     ....::.||:|.:.||...
Mosquito   579 ILKAP-----DNE---VWIWCGQYSTGDSREMAKSIAGQL-----GEYSLVMEGNETDEFFNSV- 629

  Fly  1137 GGRK------------PYDTDAEYMNYTR--------LFRCS-NERGYYTVAEKCADFCQDDLAD 1180
             |.|            ...|.|...|..:        |:||. .|.|..|: .:...|.|.||..
Mosquito   630 -GEKFLKQLKKTTTAGNIITPAVQTNVAQTWDRAVIGLYRCQLLEDGKPTM-RQIFGFSQQDLRP 692

  Fly  1181 DDIMILDNGEHVFLWMGPRCSEVEVKLAYKSA-QVYIQH----------MRIKQPERPRKLFLTM 1234
            |.|.:||.|..|::|:|.:....|....::.| |:...|          ..::|.|.|.......
Mosquito   693 DSIFLLDAGSIVYVWIGEQTVVEERAQCWELARQLIATHPVQRDTAMPIAAVRQGEEPITFVGFF 757

  Fly  1235 KNKESRRFTKC 1245
            .:.:.:||..|
Mosquito   758 DSWDRKRFESC 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380
		leucine-rich repeat	31..53	CDD:275380
		LRR	33..405	CDD:443914
		leucine-rich repeat	54..76	CDD:275380
		leucine-rich repeat	77..101	CDD:275380
		leucine-rich repeat	102..124	CDD:275380
		leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	149..171	CDD:275380
		leucine-rich repeat	172..195	CDD:275380
		leucine-rich repeat	196..220	CDD:275380
		leucine-rich repeat	221..243	CDD:275380
		leucine-rich repeat	244..266	CDD:275380
		leucine-rich repeat	267..289	CDD:275380
		leucine-rich repeat	290..314	CDD:275380
		leucine-rich repeat	315..335	CDD:275380
		leucine-rich repeat	338..360	CDD:275378
		gelsolin_S1_like	491..602	CDD:200446	26/125 (21%)
		gelsolin_like	618..706	CDD:200436	14/94 (15%)
		gelsolin_S3_like	729..828	CDD:200448	27/108 (25%)
		gelsolin_like	920..1015	CDD:200436	23/98 (23%)
		gelsolin_S5_like	1037..1141	CDD:200444	26/116 (22%)
		gelsolin_S6_like	1151..1250	CDD:200447	28/115 (24%)
qua	XP_061510394.1	None