Protein Alignment fliI and fliI

DIOPT Version :10

• Sequence 1: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_309356.5
• Gene: fliI / 1270641
• VectorBaseID: AGAMI1_002163
• Length: 1292
• Species: Anopheles gambiae
• Alignment Length: 1288
• Identity: 904/1288 - (70%)
• Similarity: 1059/1288 - (82%)
• Gaps: 42/1288 - (3%)

  Fly     3 VLPFVRGVDFTKNDFSA-TFPSSMRQMSRVQWLTLDRTQLAEIPEELGHLQKLEHLSLNHNRLEK 66
            |||||||:|||.||||. .||.:::.||.||||.||||.:..||:|:|.|.||||||:.:|:|||
Mosquito     6 VLPFVRGIDFTNNDFSEDKFPKNIKHMSGVQWLKLDRTGMDTIPDEMGKLVKLEHLSMKNNQLEK 70

  Fly    67 IFGELTELSCLRSLDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLS 131
            :||:|:||.|||||::|.|:||:..||.:||.||||||||||||:|||||||||:||.|:|||||
Mosquito    71 LFGQLSELGCLRSLNVRRNKLKSHAIPSDLFELEELTTLDLSHNRLKEVPEGLEKAKALLVLNLS 135

  Fly   132 NNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDLSHNPLELFQLRQLPSLQSL 196
            |||||:||..|||:||||||||||:|:|||||||||||.||:||.|:.|||||||||||||||||
Mosquito   136 NNQIETIPPSLFINLTDLLFLDLSNNKLETLPPQTRRLSNLQTLILNDNPLELFQLRQLPSLQSL 200

  Fly   197 EVLKMSGTQRTLLNFPTSIDSLANLCELDLSHNSLPKLPDCVYNVVTLVRLNLSDNELTELTAGV 261
            ..|:|..||||:.|||.|:|||:||.|||||.|:|.|:|..:||:..|.||||:||.|.||:..:
Mosquito   201 VCLQMRNTQRTINNFPASLDSLSNLQELDLSQNALSKVPGALYNLANLKRLNLNDNVLEELSPLI 265

  Fly   262 ELWQRLESLNLSRNQLVALPAALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSAANNLLE 326
            |...:||:||||||:|.||||.||||.:||||.||||.||||||||.||||.|||||||:||.||
Mosquito   266 ENLTKLETLNLSRNKLTALPATLCKLQELRRLYVNDNLLNFEGIPSSIGKLSALEVFSASNNELE 330

  Fly   327 MVPEGLCR-CGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRNNPELVMPPKPSEASKATSLEFY 390
            |||||||| ||:||:||||.|:|||||:|||||..::||||||||:|||||||.||.:...|.:|
Mosquito   331 MVPEGLCRGCGSLKKLNLSSNKLITLPEAIHLLTDMEQLDLRNNPDLVMPPKPIEAQRGDGLAYY 395

  Fly   391 NIDFSLQTQLRLAGAAVPPSMPSSATP-KDSTARKIRLRRGPR--SEGDQDAAKVLKGMKDVAKD 452
            |||||||||||||||.||..:..:|.. ||..|||:|||||.|  |..:||:||:||||:|:|||
Mosquito   396 NIDFSLQTQLRLAGANVPAQVQGAANAGKDPIARKLRLRRGARNDSSDNQDSAKILKGMQDIAKD 460

  Fly   453 KDNEAGAVPEDGKPESLKPKRWDESLEKPQLDYSKFFEKDDGQLPGLTIWEIENFLPNKIEEVVH 517
            |::..|...|  |.|:||||||||:||||.:|||:.||.:|||.||||:|||||||||||||..|
Mosquito   461 KNSGLGFGEE--KVENLKPKRWDETLEKPPVDYSEIFEDEDGQYPGLTVWEIENFLPNKIEEAAH 523

  Fly   518 GKFYEGDCYIVLKTKFDDLGLLDWEIFFWIGNEATLDKRACAAIHAVNLRNFLGARCRTVREEQG 582
            ||||||||||||||..||.|.|.|||:||||.:||||||||:|||||||||:|||||||:|||||
Mosquito   524 GKFYEGDCYIVLKTSHDDSGQLSWEIYFWIGTKATLDKRACSAIHAVNLRNYLGARCRTIREEQG 588

  Fly   583 DESEQFLSLFETEVIYIEGGRTATGFYTIEEMIHITRLYLVHAYGATIHLEPVAPAITSLDPRHA 647
            |||::||:||:::|.|||||||:|||||||..::|.|||.||..|..||||||..:..||||.:.
Mosquito   589 DESDEFLALFDSDVTYIEGGRTSTGFYTIENAVYIVRLYRVHDAGPNIHLEPVPVSYQSLDPGYV 653

  Fly   648 FVLDLGTHIYIWMGERSKNTLNSKARLMAEKISKTERKNKCEIQLERQGEESAEFWQGLGMT--- 709
            |:||.|.:|::|.|.||||||.||||..||||:|.|||||.||..|.|.:||.:||:.||..
Mosquito   654 FLLDTGLNIFVWYGTRSKNTLKSKARFTAEKINKHERKNKAEIYQEYQRQESLDFWRALGFADGQ 718

  Fly   710 ---SEEADAAEPPKEHVPEDYQPVQPRLYQVQLGMGYLELPQVELP----EQKLCHTLLNSKHVY 767
               .|||:...  :.||..::.||.|||||:|||||||||||||||    .:.|.||:|.||:||
Mosquito   719 GPQDEEAECLN--QSHVDPEFVPVPPRLYQIQLGMGYLELPQVELPGGGCNKTLTHTILASKNVY 781

  Fly   768 ILDCYTDLFVWFGKKSTRLVRAAAVKLSRELFNMMDRPDYALVMRVPEGNEMQIFRTKFAGWDEV 832
            |||||.||||||||||||||||||:|||:|||:|:||||||::.||.||.|.|:|::||.||:|:
Mosquito   782 ILDCYLDLFVWFGKKSTRLVRAAAIKLSQELFSMIDRPDYAMITRVQEGTETQVFKSKFTGWEEI 846

  Fly   833 MAVDFTRTAKSVAKTGANLTQWARQQETRTDLAALFMPRQSAMPLAEAEQLEEEWNYDLEMMEAF 897
            :||||||||:|||:|||:|||||:||:|:.||||||||||.||...||.||.|:|||||::||.|
Mosquito   847 IAVDFTRTAQSVARTGADLTQWAKQQQTKADLAALFMPRQPAMTPMEAAQLAEDWNYDLDVMEPF 911

  Fly   898 VLENKKFVRLPEEELGRFYTGECYVFLCRYCIPI--EEPENGSED---------------GANPA 945
            ||||||||||||||||.||||||||||||||:|:  |:..:|.||               ||: :
Mosquito   912 VLENKKFVRLPEEELGVFYTGECYVFLCRYCLPVDDEDEPDGEEDEGHDSTVAAGGPGTEGAS-S 975

  Fly   946 ADVSKSSAN-----NQPEDEIQCVVYFWQGRNAGNMGWLTFTFTLQKKFKAMFGEELEVVRIFQQ 1005
            ..:.|:|..     ..|.:||||||||||||.||||||||||||||||||:|||||||||||.||
Mosquito   976 GPIGKASLKALDPAATPAEEIQCVVYFWQGREAGNMGWLTFTFTLQKKFKSMFGEELEVVRIHQQ 1040

  Fly  1006 QENLKFMSHFKRKFIIHTGKRKDKAHTAKGKSPVEFFHLRSNGGALTTRLIQINPDAVHLNSTFC 1070
            |||||||||||.||:|..|:||:|..|.:||.||||:||||||.||.|||||:.|:|..|||.||
Mosquito  1041 QENLKFMSHFKGKFVIKNGRRKEKQRTPEGKLPVEFYHLRSNGSALCTRLIQVKPEANVLNSAFC 1105

  Fly  1071 YILHVPFETEDDSQSGIVYVWIGSKACNEEAKLVQDIAEQMFNSPWVSLQILNEGDEPENFFWVA 1135
            |||.|||||:|||:|||||||||||...|||:|:|:|||.|||:||||||||:||:|||||||||
Mosquito  1106 YILFVPFETDDDSESGIVYVWIGSKTTGEEARLIQEIAEDMFNNPWVSLQILHEGEEPENFFWVA 1170

  Fly  1136 LGGRKPYDTDAEYMNYTRLFRCSNERGYYTVAEKCADFCQDDLADDDIMILDNGEHVFLWMGPRC 1200
            |||||||||||||||:|||||||||:||:||||||:||||||||||||||||||:.||||:|.||
Mosquito  1171 LGGRKPYDTDAEYMNFTRLFRCSNEKGYFTVAEKCSDFCQDDLADDDIMILDNGDQVFLWLGSRC 1235

  Fly  1201 SEVEVKLAYKSAQVYIQHMRIKQPERPRKLFLTMKNKESRRFTKCFHGWSAFK 1253
            ||||:||||||||||||||||||||||||||||:|||||:|||||||||||.|
Mosquito  1236 SEVEIKLAYKSAQVYIQHMRIKQPERPRKLFLTLKNKESKRFTKCFHGWSAHK 1288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380	13/23 (57%)
		leucine-rich repeat	31..53	CDD:275380	13/21 (62%)
		LRR	33..405	CDD:443914	266/372 (72%)
		leucine-rich repeat	54..76	CDD:275380	14/21 (67%)
		leucine-rich repeat	77..101	CDD:275380	13/23 (57%)
		leucine-rich repeat	102..124	CDD:275380	19/21 (90%)
		leucine-rich repeat	125..148	CDD:275380	17/22 (77%)
		leucine-rich repeat	149..171	CDD:275380	19/21 (90%)
		leucine-rich repeat	172..195	CDD:275380	18/22 (82%)
		leucine-rich repeat	196..220	CDD:275380	14/23 (61%)
		leucine-rich repeat	221..243	CDD:275380	12/21 (57%)
		leucine-rich repeat	244..266	CDD:275380	11/21 (52%)
		leucine-rich repeat	267..289	CDD:275380	17/21 (81%)
		leucine-rich repeat	290..314	CDD:275380	20/23 (87%)
		leucine-rich repeat	315..335	CDD:275380	18/20 (90%)
		leucine-rich repeat	338..360	CDD:275378	17/21 (81%)
		gelsolin_S1_like	491..602	CDD:200446	86/110 (78%)
		gelsolin_like	618..706	CDD:200436	51/87 (59%)
		gelsolin_S3_like	729..828	CDD:200448	75/102 (74%)
		gelsolin_like	920..1015	CDD:200436	70/116 (60%)
		gelsolin_S5_like	1037..1141	CDD:200444	80/103 (78%)
		gelsolin_S6_like	1151..1250	CDD:200447	87/98 (89%)
fliI	XP_309356.5	None