Protein Alignment fliI and vil1

DIOPT Version :10

• Sequence 1: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001096367.1
• Gene: vil1 / 100124960
• XenbaseID: XB-GENE-965127
• Length: 824
• Species: Xenopus tropicalis
• Alignment Length: 786
• Identity: 209/786 - (26%)
• Similarity: 351/786 - (44%)
• Gaps: 113/786 - (14%)

  Fly   497 PGLTIWEIE--NFLPNKIEEVVHGKFYEGDCYIVLKT-----KFDDLGLLDWEIFFWIGNEATLD 554
            |||.||.:|  |.:|  :.|..:|.|::||||::|.|     .|      .::|.||:||::::|
 Frog    17 PGLQIWRVESMNLVP--VPENSYGNFFDGDCYVLLMTHKTGNNF------TYDIHFWVGNDSSMD 73

  Fly   555 KRACAAIHAVNLRNFLGARCRTVREEQGDESEQFLSLFETEVIYIEGGRTATGFYTIEEMIHITR 619
            ::..|||:.:.:.:.||......||.||.||:.|...|:..:||..|| .|:|...:|     |.
 Frog    74 EQGAAAIYTIQMDDHLGGAAIQHREVQGHESDTFKGYFKHGIIYKSGG-VASGMNHVE-----TN 132

  Fly   620 LY----LVHAYGATIHLEPVAPA-ITSLDPRHAFVLDLGTHIYIWMGERSKNTLNSKARLMAEKI 679
            .|    |:|..|....|....|. .:|.:....|:||||..|..|.|..|......:...:|:.|
 Frog   133 TYNVKRLLHCKGKKNVLAGEVPVEWSSFNVGDVFLLDLGKLIIQWNGPESNKQERLRGMTLAKDI 197

  Fly   680 SKTERKNKCEI-QLERQGEESAEFWQGLGMT-----SEEADAAEPPKEHVPEDYQPVQPRLYQVQ 738
            ...||..:..: .:|...||.:.....: ||     .:|...|.|  :.|.:.......:|:||.
 Frog   198 RDRERGGRSYVGVVEGDNEEQSPQLMAI-MTYVLGERKEIRGAIP--DEVVDQVAKTSIKLFQVS 259

  Fly   739 LGMGYLELPQVELPEQKLCHTLLNSKHVYILD-CYTDLFVWFGKKSTRLVRAAAVKLSRELFNMM 802
            ...|.|.:.  |:..|.|...||.....|||| ..:.:|||.||.:::..:..|:..:.......
 Frog   260 DNSGNLMVQ--EVATQPLTQDLLKHDDCYILDQAGSKIFVWKGKNASKEEKQQAMTRALNFIRAK 322

  Fly   803 DRPDYALVMRVPEGNEMQIFRTKFAGW---DEVMAVDFTRTAKSVAKTGANLTQWARQQETRTDL 864
            :.|....|....:|:|..:|:..|..|   |:...:..|.|...|||.          ::.:.|:
 Frog   323 NYPASTNVEVENDGSESAVFKQLFQKWTTKDQTTGLGKTSTVGKVAKV----------EQVKFDV 377

  Fly   865 AALFMPRQSAMPLAEAEQ-LEEEWNYDLEMMEAFVLENKKFVRLPEEELGRFYTGECYVFLCRYC 928
            .::     .|.|...|:| :.::...:.|:..   :||.:.|.:.::.||.||.|:||:.|.:|.
 Frog   378 NSM-----HAKPEVAAQQKMVDDGTGETEVWR---IENLERVLVDKQYLGHFYGGDCYLILYKYL 434

  Fly   929 IPIEEPENGSEDGANPAADVSKSSANNQPEDEIQCVVYFWQGRNAGNMGWLTFTFTLQKKFKAMF 993
            :                        ||    :...:||.||||:| :...:|.:..........:
 Frog   435 V------------------------NN----KYHYIVYMWQGRHA-SQDEITASAYQSVILDQEY 470

  Fly   994 GEELEVVRIFQQQENLKFMSHFKRKFIIHTGKRKDKAHTAKGKSPVEFFHLRSNGGALTTRLIQI 1058
            |.:...||:...:|....|:.||.|.:::.| ...:|.:::..:.:..|.:. .....:|:..::
 Frog   471 GGQPVQVRVPMGKEPAHLMAIFKGKMVVYEG-GTSRADSSEIPADIRLFQVH-GANEYSTKAFEV 533

  Fly  1059 NPDAVHLNSTFCYILHVPFETEDDSQSGIVYVWIGSKACNEEAKLVQDIAEQMFNSPWVSLQILN 1123
            ...|..|||...::|         ...|..|:|.|.....:|..:.:::|:.:.....|   ::.
 Frog   534 PVRASSLNSNDVFVL---------KTKGTCYLWCGKGCSGDERAMAKNVADIISKGEKV---VIA 586

  Fly  1124 EGDEPENFFWVALGGRKPYDTDAEYMNYT-----RLFRCSNERGYYTVAEKCADFCQDDLADDDI 1183
            ||.||.: ||:||||:..|..:......|     |||.|||:.|.: ||.:.:||.||||.:||:
 Frog   587 EGQEPSD-FWLALGGKSQYANNKRLQEETLDITPRLFECSNKTGKF-VATEISDFNQDDLDEDDV 649

  Fly  1184 MILDNGEHVFLWMGPRCSEVEVKLAYKSAQVYIQ-HMRIKQPERPRKLFLTMKNKESRRFTKCFH 1247
            .:||..:.:|:|:|...:|.|.|.|..:||.|:: |...:....|  :.:..::.|...||..|.
 Frog   650 FLLDAWDQIFMWIGKNSNETEKKEAAMTAQEYLKTHPGGRDINTP--IIVVKQDYEPPTFTGWFL 712

  Fly  1248 GWSAFK 1253
            .|..||
 Frog   713 AWDPFK 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380
		leucine-rich repeat	31..53	CDD:275380
		LRR	33..405	CDD:443914
		leucine-rich repeat	54..76	CDD:275380
		leucine-rich repeat	77..101	CDD:275380
		leucine-rich repeat	102..124	CDD:275380
		leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	149..171	CDD:275380
		leucine-rich repeat	172..195	CDD:275380
		leucine-rich repeat	196..220	CDD:275380
		leucine-rich repeat	221..243	CDD:275380
		leucine-rich repeat	244..266	CDD:275380
		leucine-rich repeat	267..289	CDD:275380
		leucine-rich repeat	290..314	CDD:275380
		leucine-rich repeat	315..335	CDD:275380
		leucine-rich repeat	338..360	CDD:275378
		gelsolin_S1_like	491..602	CDD:200446	39/111 (35%)
		gelsolin_like	618..706	CDD:200436	24/93 (26%)
		gelsolin_S3_like	729..828	CDD:200448	26/99 (26%)
		gelsolin_like	920..1015	CDD:200436	19/94 (20%)
		gelsolin_S5_like	1037..1141	CDD:200444	24/103 (23%)
		gelsolin_S6_like	1151..1250	CDD:200447	36/104 (35%)
vil1	NP_001096367.1	gelsolin_S1_like	17..121	CDD:200446	39/111 (35%)
		gelsolin_S2_like	136..227	CDD:200445	22/91 (24%)
		gelsolin_S3_like	253..348	CDD:200448	26/96 (27%)
		gelsolin_S4_like	392..492	CDD:200449	28/131 (21%)
		gelsolin_S5_like	515..603	CDD:200444	24/101 (24%)
		gelsolin_S6_like	619..715	CDD:200447	35/98 (36%)
		VHP	789..824	CDD:460493