DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tty and PVRIG

DIOPT Version :9

Sequence 1:	NP_542443.4	Gene:	tty / 33109	FlyBaseID:	FBgn0015558	Length:	970	Species:	Drosophila melanogaster
Sequence 2:	NP_076975.2	Gene:	PVRIG / 79037	HGNCID:	32190	Length:	326	Species:	Homo sapiens

Alignment Length:	140	Identity:	32/140 - (22%)
Similarity:	42/140 - (30%)	Gaps:	36/140 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   503 HTLGRLPSHNHSPTHMTGPNNAAAVAAAANAAANMPPTTQAAQQQQQQQAQQQQQQAQQQLGGPQ 567
            |.|.|   |.|.|.....|:..:..|..|.|         .|..|..|.|.............|.
Human   191 HLLRR---HKHRPAPRLQPSRTSPQAPRARA---------WAPSQASQAALHVPYATINTSCRPA 243

  Fly   568 PIYCHHPHQHPH---------PHPHQHPHSHSAAAVAAA---VQHQHAIYHQQQAQQYGTYTTAA 620
            .:...|||..|.         .|..|.|.:.::..:.|.   |..::.:|.|            |
Human   244 TLDTAHPHGGPSWWASLPTHAAHRPQGPAAWASTPIPARGSFVSVENGLYAQ------------A 296

  Fly   621 HHAPHHLGPG 630
            ...|.|.|||
Human   297 GERPPHTGPG 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tty	NP_542443.4	Tweety_N	10..429	CDD:143653
PVRIG	NP_076975.2	Ig	57..145	CDD:325142
		Atrophin-1	<84..324	CDD:331285	32/140 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..326		6/11 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4433
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900