Protein Alignment tty and ttyh1

DIOPT Version :9

• Sequence 1: NP_542443.4
• Gene: tty / 33109
• FlyBaseID: FBgn0015558
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_001072899.1
• Gene: ttyh1 / 780361
• XenbaseID: XB-GENE-940450
• Length: 536
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 135/549 - (24%)
• Similarity: 251/549 - (45%)
• Gaps: 51/549 - (9%)

  Fly    19 LLHALPHYNITFHKINSTFRPNDEIYLESLGILGSVPAALLIVSLLGLLFYLMTRCC-------D 76
            :||.:||.|..|..:::.|.|.:..|.::|..|.|:....|.:||:.:..||:..||       |
 Frog    15 ILHQVPHTNFQFEVVDNQFAPQEWPYQQALLFLASIAGLCLAISLILICVYLIRFCCCSSQEDDD 79

  Fly    77 RKPRPAHSITSLKVALSIVTVMCCAAIGLGLYGNDDLHNGLLEVLTAGRKVDNLVTTIRNQTHIL 141
            .|   :|.:..:..:.....::|||.||:|.|||.:.::|:.:|..:....::.:|:|.......
 Frog    80 SK---SHRVCCVTWSCVAAVIICCAGIGIGFYGNSETNDGVYQVTYSLMNANHTLTSINLLISDT 141

  Fly   142 ENTLTNRIRPQLVELADIFDQPVSNQTALSKLFVSLNIVQGNVTLATNAASDIR-------RPLM 199
            ...|::.:|..|.:|.:||    |.:|   :..|.:...:..|.......::|.       .|..
 Frog   142 VELLSSVVRSDLTQLEEIF----SKRT---EFLVMIRNTRRQVESVAQQLAEISFWKGPEPNPNA 199

  Fly   200 GISMTHFLTRGDQWELIRWPGTVATLALLLVLCAVLLVGVARHSRCALILFSVCGLLAVTGSWLM 264
            .....:|:      |..||...:..|.|.|::|...|:|:|:..:..:|:.:|.....:..||..
 Frog   200 LAEQVNFI------EDYRWLAYILLLLLDLIICLFTLLGLAKQIKWLVIVMTVVSFFVLLLSWGS 258

  Fly   265 SGLYLSSSVAVGDLCISPADFLV--STAPRDLPTNVLLHYTQCEPGHTNPFTQRLRESQNSLNNA 327
            .||.::::|.:.|.|..|..:::  :.|..::..::|.:|..|....||||.|||..||.:|:|.
 Frog   259 MGLEMATAVGLSDFCSDPDAYVMNQTQAITNINPDILQYYISCNQDVTNPFRQRLTMSQRALSNI 323

  Fly   328 RSAMATVMKISLVLFKSSGLQPKLGAVNADLNSSERLLTQLTALVDCKAVHHNFLAAARGLCEGG 392
            .|.:..:.:.::..|.::  :..|..|...||::|.....|.||::|:.:|.:::.|.:|||..|
 Frog   324 HSQLHGLEREAVPQFPTA--EKNLLVVQGMLNTTEGNFHHLVALLNCRGLHKDYVDALKGLCYDG 386

  Fly   393 LLGLVLMLIASFIAAILLTIMVWVDSHTWIYIRKRN-DYAQVDEPSYISHPAPQNHQQMMNAART 456
            :.|::.:|:.||::|:..|..:......|...:.|: ||..:||....:   ||..::|::..
 Frog   387 MEGILFLLLFSFLSALSFTAAICSLPRAWKRFQNRDLDYDDMDEDDPFN---PQARREMLHVT-- 446

  Fly   457 LPRNHNGHFSPPVISGSHTL-QHPSKRQQHEMMAHAHIQQNMR----AMGTHTLGRLP-SHNHSP 515
             .|.|    .|...|.|.:. .|.|.|.....:::|.:.|.|.    :.|......:| ....||
 Frog   447 -GRPH----LPSFYSYSSSCDSHSSLRVSAPPISNAPVSQYMNQSALSSGNPRFENIPLIDRQSP 506

  Fly   516 THMTGPNNAAAVAAAANAAANMPPTTQAA 544
            .....|:...:..:|.....:.|..|..|
 Frog   507 PPSYSPSMRTSFISATQEETDTPCRTDVA 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tty	NP_542443.4	Tweety_N	10..429	CDD:143653	108/426 (25%)
ttyh1	NP_001072899.1	Tweety	26..421	CDD:368183	102/412 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3775
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	186	1.000	Inparanoid score	I3793
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm9568
Panther	1	1.100	-	-	LDO	PTHR12424
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070