Protein Alignment CG1486 and Pdxdc1

DIOPT Version :10

• Sequence 1: NP_608450.1
• Gene: CG1486 / 33108
• FlyBaseID: FBgn0031174
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: XP_011244355.1
• Gene: Pdxdc1 / 94184
• MGIID: 1920909
• Length: 795
• Species: Mus musculus
• Alignment Length: 845
• Identity: 246/845 - (29%)
• Similarity: 391/845 - (46%)
• Gaps: 166/845 - (19%)

  Fly    42 LAELELRSSQVLQRLENVKVSTTPESPNPVENEEEAGERVTSEDLLPAKHRVPSDILKSLEQLVS 106
            |||:.....:.::.||.          :|...|||.|::..||| :|...:.....:.|:.|||.
Mouse    13 LAEMGKNLKEAMRMLEK----------SPRRTEEENGKKPVSED-IPGPLQGSGQDMVSILQLVQ 66

  Fly   107 ---YTDSDDDPEFP-LPALDDVSHLALISHSIVAYLSHLDRQQLLRVTNSISGDATRWLGTLFHF 167
               :.|.|::|:.. :..:.:..|:||:.||:.||:|.||:::|.::|..|..|.|.||..:|.:
Mouse    67 NLMHGDEDEEPQSTRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSDTTLWLRRIFRY 131

  Fly   168 AHPASSFHADNADAVLRTVRLAIVARCPGYLEGGIPAL--AQPTFYISENTTPMRLHYACRQLGI 230
            .:..:.||.:..:.:.:..||||.:|...::..|...|  .:|..|:|....|....|.|.|||:
Mouse   132 ENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGL 196

  Fly   231 PLEAIKVIPEHSQSGT---MDVTLLQKQIQQDVGNNRTPLLVVADIGASLCGYVDNLLRLRDVCK 292
            |...:..:|.::..|:   |||..|:|.|:.||...|.|||:||:.|.:..|:.|.:.||:::|:
Mouse   197 PFPCLCRVPCNTMFGSQHQMDVAFLEKLIKDDVERGRLPLLLVANAGTAAVGHTDKIGRLKELCE 261

  Fly   293 AHNMWLHASGHGLAALVCAQNQGHVEEVL------HSMALNLGSWLGVPSLPIVLLHRPLQNSAL 351
            .:.:|||..|..||.|..    |:|...:      .||.|..|.|||:|::|.|.|::
Mouse   262 QYGIWLHVEGVNLATLAL----GYVSSSVLAATKCDSMTLTPGLWLGLPAVPAVTLYK------- 315

  Fly   352 SAFESDPIL-----------SRRLNALSLWTSLQALGRKAIAERLHVAFQTCSILFEIASKCEGI 405
               ..||.|           :.:|.||.||.|||.||...|.||:..|......|.|...|.:.|
Mouse   316 ---HDDPALTLVAGLTSNKPADKLRALPLWLSLQYLGLDGIVERIKHACHLSQRLQESLKKVDHI 377

  Fly   406 RVLSHTPGAQTGASLSDVIQSPFDVQALFDAAAPVVAYQF--------DGSTTIPLGGSGSSAAA 462
            ::|           :.|.:.|            |||.::|        .....:|:  |..:.||
Mouse   378 KIL-----------VEDELSS------------PVVVFRFFQELPASDSAFKAVPV--SNIAPAA 417

  Fly   463 AAAERETAEGLKPLEKINNASYFDRLNSWLGQILQRDCPNFDFEVIEHPTHGSCIRYCPLEL--G 525
            ...||.:.               |.||.|||:.|::..|.....||:....|:|:|:.||..  |
Mouse   418 VGRERHSC---------------DALNRWLGEQLKQLVPQCGLTVIDLEVDGTCVRFSPLMTAEG 467

  Fly   526 LGEQPPSSENLESFAQSLEAHVDILRATIKHKARFIHLVECSDVLRLVPLPEWAGMGGVRFV--- 587
            ||.:   .|:::.....:::.:.:|..|::.:..|...||.:..|..|..|.|.|:|.||:.
Mouse   468 LGTR---GEDVDQLITCIQSKLPVLTCTLQLREEFKQEVEGTAGLLYVDDPNWPGIGVVRYEHAN 529

  Fly   588 ---------PEGWESLLTDQAKTELNKLNIDLVEALKSTDNAFSLG-EGTDGLICVRFGMVTHET 642
                     ||| |.:.|...| :||:|..||         .|.:| |......|:..||.:.:.
Mouse   530 DDDTSLKSDPEG-EKIHTGLLK-KLNELESDL---------TFKIGPEYKSMKSCIYIGMASDDV 583

  Fly   643 EVEELLDLVVTVGKSVQENSRVLDTMSEIVKKGIEAVTADLQRESEEKLWQEGILRHVPVVGRVF 707
            :|.||::.:....:.::||||:|:.|:|:|:|||:.....||:.:||:|.:||:||.:||||.|.
Mouse   584 DVSELVETIAVTAREIEENSRLLENMTEVVRKGIQEAQVQLQKANEERLLEEGVLRQIPVVGSVL 648

  Fly   708 NWWSPPAKESGIKGRSLNLTQGVVESTENIYKYHMQMTGATAHQLPANRSPPTPMVQTPVVAPAL 772
            ||:||  .::..||||.|||.|.:||||..|.:.:|.||.|        .||||:
Mouse   649 NWFSP--VQASQKGRSFNLTAGSLESTEYTYVHKVQGTGVT--------PPPTPL---------- 693

  Fly   773 PPVFPTVEPVPGNGNGSGASEGTPVQ---SGEASGSMPAASGAAPSAAPTQNHVDHARTVSQSSA 834
                           |:.:.:..||:   .|:...........|.|...:.:|::....|.|.|:
Mouse   694 ---------------GTRSKQRLPVRLMSLGQKPFKRSLRGSDAVSETSSVSHIEDLEKVEQLSS 743

  Fly   835  834
            Mouse   744  743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1486	NP_608450.1	GadA	<157..410	CDD:439846	87/274 (32%)
Pdxdc1	XP_011244355.1	GadA	<172..479	CDD:439846	105/363 (29%)