Protein Alignment CG1486 and Tdc2

DIOPT Version :10

• Sequence 1: NP_608450.1
• Gene: CG1486 / 33108
• FlyBaseID: FBgn0031174
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 830
• Identity: 158/830 - (19%)
• Similarity: 252/830 - (30%)
• Gaps: 285/830 - (34%)

  Fly   112 DDPEFPLPALDDVSHLALISHSIVAYLSHLDRQQLLRVTNSISGDATRWLGTLFHFAHPASSFHA 176
            |..||....::.|.:       |..||..|:.:   |||.|:..      |.|.|...|.:....
  Fly     2 DSTEFRKRGMEMVEY-------ICNYLETLNER---RVTPSVEP------GYLRHLLPPEAPQEP 50

  Fly   177 DNADAVLRTVRLAIVARCPGYLEGGIPALAQPTFYISENTTPMRLHYACRQLGIPLEAIKVIPEH 241
            ::.|.::|.|...|:.        |:.....|.|:                            .:
  Fly    51 EDWDQIMRDVEDKIMP--------GVTHWQHPRFH----------------------------AY 79

  Fly   242 SQSGTMDVTLLQKQIQQDVGNNRTPLLVVADIGASLCGYVDNLLRLRDVCKAHNMWLHASGHGLA 306
            ..:|....::|...:...:|          .||.|                    |       .|
  Fly    80 FPAGNSFPSILGDMLGDGIG----------CIGFS--------------------W-------AA 107

  Fly   307 ALVCAQNQGHVEEVLHSMALN-LGSWLGVPSLPIVLLHRPLQNSALSAFESDPILSRRLNALSLW 370
            :..|.:        |.::.|: ||..:|:|...:.|.........:....|:.:|...|.|.:
  Fly   108 SPACTE--------LETIVLDWLGKAIGLPDHFLALKEGSTGGGVIQTSASECVLVTMLAARA-- 162

  Fly   371 TSLQALGR-KA---IAERLHVAFQTCSILFEIASKC---------EGIRVLSHTPGAQ-TGASLS 421
               |||.| ||   ..|..|:..:..:...:.|..|         ..:|:|.....|. .|.::.
  Fly   163 ---QALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSCVEKAAMICFVKLRILEPDDDASLRGQTIY 224

  Fly   422 DVIQSPFDVQALFDAAAPVVAYQFDGSTTIPLGGSGSSA----------------------AAAA 464
            :.::.. ::|.|         ..|..|||  ||.:||.|                      ||.|
  Fly   225 EAMEED-ELQGL---------VPFFVSTT--LGTTGSCAFDNLPEIGKQLQRFPGVWLHVDAAYA 277

  Fly   465 AERETAEGLKPLEK-INNASYFD-RLNSWLGQILQRDCPNF--------------DFEVIEHPTH 513
            ........||||.| |..|..|: ..|.||  :...||...              |...::|...
  Fly   278 GNSFICPELKPLLKGIEYADSFNTNPNKWL--LTNFDCSTLWVRDRIRLTSALVVDPLYLKHGYS 340

  Fly   514 GSCIRYCPLELGLGEQPPSSE---NLESFAQSLEAHVDILRATIKHKARFIHLV-------ECSD 568
            .:.|.|....:.|..:..|.:   .|.|:..|...|  .:|..||...||..||       .|:.
  Fly   341 DAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQH--YIRHHIKLAKRFEELVLKDKRFEICNQ 403

  Fly   569 VLRLVPLPEWAGMGGVRFVPEGWESLLTDQAKTELNKLNIDLVEALKSTDNAFSLGEGTDGLICV 633
            |          .:|.|.|..:|            .:|||..|:..:..:.....:.........:
  Fly   404 V----------KLGLVCFRLKG------------SDKLNEKLLSIINESGKLHMVPASVGDRYII 446

  Fly   634 RFGMVTHETEVEEL---LDLVVTVGKSVQENSRVLDTMSEIVKKGIEAVTADLQRESEEKLWQEG 695
            ||..|......|::   .|::|.....:.|..: .|.:|||           :.|:.::.|.|:
  Fly   447 RFCAVAQNATAEDIDYAWDIIVDFANELLEKEQ-HDELSEI-----------MNRKKQDTLAQK- 498

  Fly   696 ILRHVPVVGRVFNWWSPPAKESGIKGRSLNLTQGVVESTENIYKYHMQMTGATAHQLPANRSPPT 760
                                      ||..:.   :.|...||.             ||.....|
  Fly   499 --------------------------RSFFVR---MVSDPKIYN-------------PAINKAGT 521

  Fly   761 PMVQ----TPVVAPALPPVFPTVEPVPGNG----------NGSGASEGTPV-------QSGEASG 804
            |.:.    :|||:....|:..|...|..|.          |.:...:|:.|       .:.....
  Fly   522 PKLSMELPSPVVSRGSAPIIRTQSSVDHNSWISWPLAFLFNSNNEEKGSNVSLRFRHLDTNVRPS 586

  Fly   805 SMPAASGAAPSAAPTQNHVDHARTVSQSSAASS--TVPELVAASSAINNN 852
            |....|||..|.:| :|.:|:.....|.....|  ..|..|..:|:..:|
  Fly   587 SSRRNSGAGSSPSP-ENELDYVNVQQQQMEQRSPRRSPMAVRKASSTRDN 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1486	NP_608450.1	GadA	<157..410	CDD:439846	43/266 (16%)
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	94/496 (19%)