DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dd and ctdspl3

DIOPT Version :9

Sequence 1:	NP_608449.1	Gene:	Dd / 33107	FlyBaseID:	FBgn0029067	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	XP_021335375.1	Gene:	ctdspl3 / 571337	ZFINID:	ZDB-GENE-141215-56	Length:	360	Species:	Danio rerio

Alignment Length:	182	Identity:	64/182 - (35%)
Similarity:	97/182 - (53%)	Gaps:	9/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 TLVLDLDETLIHSHHNAMPRNTVKPGTPHDFTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWYDL 126
            ||||||||||:.|..|.:|        ..::|.......:..:.:|..||||..||..:::.:::
Zfish   183 TLVLDLDETLVFSSLNVIP--------DAEYTFNTRFQDHKYKVYVILRPHVREFLQAMTKHFEM 239

  Fly   127 VVFTASMEIYGAAVADKLDNGRNILRRRYYRQHCTPDYGSYTKDLSAICSDLNRIFIIDNSPGAY 191
            .|:|::.:.|...:.|.||..:.:.|.|.|:..|....|.|.|||:.:..||::..|:||:|..:
Zfish   240 FVYTSAKKEYAEKIVDILDPNKKLFRHRLYQDDCACVLGHYIKDLTILERDLSKTVILDNAPHTF 304

  Fly   192 RCFPNNAIPIKSWFSDPMDTALLSLLPMLDALRFTNDVRSVL-SRNLHLHRL 242
            .....|.||||||..|..|..|..|:|.::.|...:|.|:|| .|..|.|||
Zfish   305 PYHLMNMIPIKSWIGDQEDRELQKLIPYMEKLVHADDFRNVLKKRTDHFHRL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dd	NP_608449.1	HIF-SF_euk	60..228	CDD:274055	55/165 (33%)
ctdspl3	XP_021335375.1	Atrophin-1	<19..182	CDD:331285
ctdspl3	XP_021335375.1	NIF	183..343	CDD:308590	56/167 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820