DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dd and ctdspl2a

DIOPT Version :9

Sequence 1:	NP_608449.1	Gene:	Dd / 33107	FlyBaseID:	FBgn0029067	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001071012.1	Gene:	ctdspl2a / 558181	ZFINID:	ZDB-GENE-061013-647	Length:	469	Species:	Danio rerio

Alignment Length:	219	Identity:	75/219 - (34%)
Similarity:	110/219 - (50%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FMFNRQVRAFIQYQPVKYELFPLSPVSRHRLSLVQRKTLVLDLDETLIHSHHNAMPRNTVKPGTP 89
            :.|.:.|....:.|..:....||...|....|      |||||||||:|...|.:....:
Zfish   261 YFFIKHVPPLTEEQLTRKPALPLKTRSTPEFS------LVLDLDETLVHCSLNELEDAAL----- 314

  Fly    90 HDFTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWYDLVVFTASMEIYGAAVADKLDNGRNILRRR 154
               |..|.......:.:|..||....||:.:||.|::::||||.::|...:.:.||..:.::|.|
Zfish   315 ---TFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHR 376

  Fly   155 YYRQHCTPDYGSYTKDLSAICSDLNRIFIIDNSPGAYRCFPNNAIPIKSWFSDPMDTALLSLLPM 219
            .:|:||....|:|.|||:.:..||::..||||||.|:....:|.|||:|||.|..|..||.|:|.
Zfish   377 LFREHCVCVQGNYIKDLNILGRDLSKTVIIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPF 441

  Fly   220 LDAL-RFTNDVRSVLSRNLHLHRL 242
            |:.| ....|||..:.....||.|
Zfish   442 LEKLVELNEDVRPYIRERFRLHDL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dd	NP_608449.1	HIF-SF_euk	60..228	CDD:274055	62/168 (37%)
ctdspl2a	NP_001071012.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	231..250
		HIF-SF_euk	290..445	CDD:274055	62/168 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820