DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dd and Ctdsp2

DIOPT Version :9

Sequence 1:	NP_608449.1	Gene:	Dd / 33107	FlyBaseID:	FBgn0029067	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001106941.1	Gene:	Ctdsp2 / 52468	MGIID:	1098748	Length:	270	Species:	Mus musculus

Alignment Length:	176	Identity:	72/176 - (40%)
Similarity:	103/176 - (58%)	Gaps:	9/176 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 RKTLVLDLDETLIHSHHNAMPRNTVKPGTPHDFTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWY 124
            |..:|:||||||:||        :.||....||.|.|.|:....:.:|.|||:||.||..:.:.:
Mouse   100 RICVVIDLDETLVHS--------SFKPINNADFIVPVEIEGTTHQVYVLKRPYVDEFLRRMGELF 156

  Fly   125 DLVVFTASMEIYGAAVADKLDNGRNILRRRYYRQHCTPDYGSYTKDLSAICSDLNRIFIIDNSPG 189
            :.|:||||:..|...|.|.||. ..:.|.|.:|:.|....|.|.||||.:..||.:..|:||||.
Mouse   157 ECVLFTASLAKYADPVTDLLDR-CGVFRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNSPA 220

  Fly   190 AYRCFPNNAIPIKSWFSDPMDTALLSLLPMLDALRFTNDVRSVLSR 235
            :|...|.||:|::|||.|..||.||:|:|:.:.|..|:||.:.|.:
Mouse   221 SYIFHPENAVPVQSWFDDMADTELLNLIPVFEELSGTDDVYTSLGQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dd	NP_608449.1	HIF-SF_euk	60..228	CDD:274055	69/167 (41%)
Ctdsp2	NP_001106941.1	HIF-SF_euk	100..259	CDD:274055	69/167 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820