DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dd and ctdspl2

DIOPT Version :9

Sequence 1:	NP_608449.1	Gene:	Dd / 33107	FlyBaseID:	FBgn0029067	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001008438.1	Gene:	ctdspl2 / 493278	XenbaseID:	XB-GENE-950101	Length:	466	Species:	Xenopus tropicalis

Alignment Length:	215	Identity:	77/215 - (35%)
Similarity:	112/215 - (52%)	Gaps:	22/215 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FIQYQPVKYELFPLSPVSRHR---LSLVQRKT----LVLDLDETLIHSHHNAMPRNTVKPGTPHD 91
            ||::.|      ||:....:|   |.|..|.|    |||||||||:|...|.:....:
Frog   260 FIKHVP------PLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAAL------- 311

  Fly    92 FTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWYDLVVFTASMEIYGAAVADKLDNGRNILRRRYY 156
             |..|.......:.:|..||....||:.:||.|::::||||.::|...:.:.||..:.::|.|.:
Frog   312 -TFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKRLVRHRLF 375

  Fly   157 RQHCTPDYGSYTKDLSAICSDLNRIFIIDNSPGAYRCFPNNAIPIKSWFSDPMDTALLSLLPMLD 221
            |:||....|:|.|||:.:..||::..||||||.|:....:|.|||:|||.|..|..||.|:|.|:
Frog   376 REHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDKELLKLVPFLE 440

  Fly   222 AL-RFTNDVRSVLSRNLHLH 240
            .| ....|||..:.....||
Frog   441 NLVELNEDVRPHIRDRFRLH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dd	NP_608449.1	HIF-SF_euk	60..228	CDD:274055	64/172 (37%)
ctdspl2	NP_001008438.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	211..238
		HIF-SF_euk	287..442	CDD:274055	61/162 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920