DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dd and ctdspl2b

DIOPT Version :9

Sequence 1:	NP_608449.1	Gene:	Dd / 33107	FlyBaseID:	FBgn0029067	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001082795.1	Gene:	ctdspl2b / 323089	ZFINID:	ZDB-GENE-030131-1809	Length:	460	Species:	Danio rerio

Alignment Length:	219	Identity:	75/219 - (34%)
Similarity:	111/219 - (50%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FMFNRQVRAFIQYQPVKYELFPLSPVSRHRLSLVQRKTLVLDLDETLIHSHHNAMPRNTVKPGTP 89
            :.|.:.|....:.|..:....||...|....|      |||||||||:|...|.:....:
Zfish   252 YFFIKHVPPLTEEQLTRKPALPLKTRSTPEFS------LVLDLDETLVHCSLNELDDAAL----- 305

  Fly    90 HDFTVKVTIDRNPVRFFVHKRPHVDYFLDVVSQWYDLVVFTASMEIYGAAVADKLDNGRNILRRR 154
               |..|.......:.:|..||....||:.:||.|::::||||.::|...:.:.||..:.::|.|
Zfish   306 ---TFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHR 367

  Fly   155 YYRQHCTPDYGSYTKDLSAICSDLNRIFIIDNSPGAYRCFPNNAIPIKSWFSDPMDTALLSLLPM 219
            .:|:||....|:|.|||:.:..||::..||||||.|:....:|.|||:|||.|..|:.||.|:|.
Zfish   368 LFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPF 432

  Fly   220 LDAL-RFTNDVRSVLSRNLHLHRL 242
            |:.| ....|||..:.....||.|
Zfish   433 LEKLVELNEDVRPHVRERFRLHDL 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dd	NP_608449.1	HIF-SF_euk	60..228	CDD:274055	62/168 (37%)
ctdspl2b	NP_001082795.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..231
		HIF-SF_euk	281..436	CDD:274055	62/168 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920