DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt6 and Gk5

DIOPT Version :9

Sequence 1:	NP_608447.1	Gene:	Rpt6 / 33105	FlyBaseID:	FBgn0020369	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_008764796.1	Gene:	Gk5 / 367146	RGDID:	1311223	Length:	534	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	59/318 - (18%)
Similarity:	111/318 - (34%)	Gaps:	71/318 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 KILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPEL-------------FD 175
            |::...|.  :...::..|.|::|.. |.:|      :|:..:|:....|             |:
  Rat   237 KLIATMVS--IPFSILPPVRDTSYNF-GSVD------EEIFGVPIPVVALVGDQQSAMFGECCFE 292

  Fly   176 ALGIAQPKGVLLYGPPGTGKT----------LLARAVAHHTECTFIRVSGSELVQKFIGE-GSRM 229
            ...:....|...:....||||          |:...:.|...|         |.:...|: |:.:
  Rat   293 TGDVKLTMGTGTFLDINTGKTPQHVNGGFYPLIGWKIGHELVC---------LAEGNAGDTGTAI 348

  Fly   230 V----RELFVMAREHAPSIIFMDEIDSIGSSRIESGSG-----GDSEVQRTMLELLNQLDGFEAT 285
            |    .:||..|.|.....:.::  ||.|...:.|.||     .|.....:.:.|.:....:...
  Rat   349 VWAQKLDLFTDAAETEKMALSLE--DSEGVYFVPSFSGLQAPLNDPCACASFMGLKHSTSKYHLV 411

  Fly   286 KNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEL- 349
            :.|...:|.....:.|       .:.|:|:.|..|..|...:.. ::..|.:|..:...||...
  Rat   412 RAILESIAFRNKQLYD-------MLQREIQIPVTNIRADGGVCN-NAFVMQMTSDLINEKIDRPA 468

  Fly   350 ---MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLW 404
               |.....|.:.|:.  .|.:|.:|....:.|.:.   |.|..:|..|..::::. |
  Rat   469 HFDMSCLGAASLAGLA--VGFWADKEELQKLRQSEM---VFKPQRKWQEYEVNMEN-W 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	RPT1	17..403	CDD:224143	58/315 (18%)
		SlyX	<27..>69	CDD:294687
		AAA_16	152..>205	CDD:289934	11/75 (15%)
		AAA	185..317	CDD:278434	28/151 (19%)
Gk5	XP_008764796.1	GlpK	23..530	CDD:223628	59/318 (19%)
Gk5	XP_008764796.1	FGGY_GK5_metazoa	25..527	CDD:212665	59/318 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900