DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt6 and psmc6

DIOPT Version :9

Sequence 1:	NP_608447.1	Gene:	Rpt6 / 33105	FlyBaseID:	FBgn0020369	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001003832.1	Gene:	psmc6 / 321585	ZFINID:	ZDB-GENE-030131-304	Length:	389	Species:	Danio rerio

Alignment Length:	385	Identity:	184/385 - (47%)
Similarity:	253/385 - (65%)	Gaps:	7/385 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 AYHKGEGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVV 76
            |.::.:|.:.|..:.:|..::     ...|:.|:.|..||..:......:|:.||..|..||||:
Zfish     2 AENREKGLQDYRKKLLEHKEI-----DGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVL 61

  Fly    77 KPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEK 141
            |.:.::|.:||.....::||...:.:|.:.:.|..||||...:.|:.:.||.:|||||..|..|.
Zfish    62 KQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHED 126

  Fly   142 VPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 206
            ....:|..:|||.:||:|::||||||:.:||||..:||..|||.||||||||||||||||||...
Zfish   127 PGSVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL 191

  Fly   207 ECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRT 271
            :|.|::|..|.:|.|:|||.:|::||:|..||:|.|.||||||||:||..|...|:..|.|:|||
Zfish   192 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRT 256

  Fly   272 MLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN 336
            ::|||||:|||:....:|:||||||.|.||||||||||:||||....|||:||||||||||..:.
Zfish   257 LMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIELPNEQARLDILKIHSGPIT 321

  Fly   337 LTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEK 396
            ....|:...|.:|..|.:||:::.|||||||:|:|....:||||||..||.||  .||:|
Zfish   322 KHGDIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHEYVTQEDFMKAVRKV--ADSKK 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	RPT1	17..403	CDD:224143	183/380 (48%)
		SlyX	<27..>69	CDD:294687	9/41 (22%)
		AAA_16	152..>205	CDD:289934	38/52 (73%)
		AAA	185..317	CDD:278434	82/131 (63%)
psmc6	NP_001003832.1	RPT1	1..387	CDD:224143	184/385 (48%)
psmc6	NP_001003832.1	AAA	171..303	CDD:278434	82/131 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920