DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rpt6 and ATAD2

DIOPT Version :9

Sequence 1:NP_608447.1 Gene:Rpt6 / 33105 FlyBaseID:FBgn0020369 Length:405 Species:Drosophila melanogaster
Sequence 2:NP_054828.2 Gene:ATAD2 / 29028 HGNCID:30123 Length:1390 Species:Homo sapiens


Alignment Length:424 Identity:130/424 - (30%)
Similarity:203/424 - (47%) Gaps:107/424 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 RMEIESAYHKGEGFRSYYIQKIEELQLVV------------AEKHQNLRRLQAQRNELN--AKVR 56
            |..:.||     |.||.|.:::...:..:            .|:|...||.:::...:|  ..:.
Human   332 RYRLSSA-----GPRSPYCKRMNRRRHAIHSSDSTSSSSSEDEQHFERRRKRSRNRAINRCLPLN 391

  Fly    57 MLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYT 121
            ..::||     :|.|       .|:.|:       |..:.|:|                      
Human   392 FRKDEL-----KGIY-------KDRMKI-------GASLADVD---------------------- 415

  Fly   122 LHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVL 186
                 |.::|..|           .::.||||...|..:||::..|:.:||:|:...|..|:|.|
Human   416 -----PMQLDSSV-----------RFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCL 464

  Fly   187 LYGPPGTGKTLLARAVAHHTECT-------FIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSI 244
            .||||||||||:|||:|:  ||:       |....|::.:.|::||..|.:|.||..|.:..|||
Human   465 FYGPPGTGKTLVARALAN--ECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSI 527

  Fly   245 IFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGR 309
            ||.||||.:...|........|.:..|:|.|   :||.::...|.||.||||:|.:||||.||||
Human   528 IFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGLDSRGEIVVIGATNRLDSIDPALRRPGR 589

  Fly   310 IDRKIEFPPPNEEARLDILKIHSRKMNLTRGIN--LRKIAELMPGASGAEVKGVCTEAGMYALRE 372
            .||:..|..|::|||.:|||||:|..| .:.::  |.::||...|..||::|.:|.||.:.|||.
Human   590 FDREFLFSLPDKEARKEILKIHTRDWN-PKPLDTFLEELAENCVGYCGADIKSICAEAALCALRR 653

  Fly   373 R----------------RVHVTQEDFEMAVAKVM 390
            |                .::::.:|||:|:.|::
Human   654 RYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMI 687

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rpt6NP_608447.1 RPT1 17..403 CDD:224143 127/413 (31%)
SlyX <27..>69 CDD:294687 7/55 (13%)
AAA_16 152..>205 CDD:289934 27/52 (52%)
AAA 185..317 CDD:278434 61/138 (44%)
ATAD2NP_054828.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 40..63
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 216..380 11/52 (21%)
AAA 459..600 CDD:214640 64/145 (44%)
AAA 464..598 CDD:278434 62/138 (45%)
COG5076 <915..1153 CDD:227408
Bromo_AAA 987..1097 CDD:99957
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1124..1163
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1181..1242
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0554
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.