Protein Alignment Rpt6 and Spg7

DIOPT Version :10

• Sequence 1: NP_608447.1
• Gene: Rpt6 / 33105
• FlyBaseID: FBgn0020369
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_694816.3
• Gene: Spg7 / 234847
• MGIID: 2385906
• Length: 781
• Species: Mus musculus
• Alignment Length: 260
• Identity: 102/260 - (39%)
• Similarity: 162/260 - (62%)
• Gaps: 4/260 - (1%)

  Fly   146 TYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTF 210
            :::.|.|:.:...|::|.::. :|.||.|..||...|||.||.||||.||||||:|||...:..|
Mouse   307 SFQDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPF 370

  Fly   211 IRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSG-GDSEVQRTMLE 274
            :.::|.|.|:...|.|:..||.||..||..||.|:::||||::|..|..|.|| .::|.::|:.:
Mouse   371 LAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTSMSGFSNTEEEQTLNQ 435

  Fly   275 LLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTR 339
            ||.::||...|.::.|:.:|||.|:||.||:||||:||.:....|..:.|.:|.:.|.:.:.||:
Mouse   436 LLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFIDLPTLQERREIFEQHLKGLKLTQ 500

  Fly   340 GINL--RKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKK 402
            ..:.  :::|||.||.|||::..:|.||.::|.||....|...:||.||.:|:...::|:..:.|
Mouse   501 PSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTFNFEYAVERVIAGTAKKSKILSK 565

  Fly   403  402
            Mouse   566  565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	PRK03992	23..399	CDD:179699	101/255 (40%)
Spg7	NP_694816.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..56
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..135
		HflB	147..749	CDD:440233	102/260 (39%)
		Interaction with PPIF. /evidence=ECO:0000250|UniProtKB:Q9UQ90	701..781