DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt6 and atad2

DIOPT Version :9

Sequence 1:	NP_608447.1	Gene:	Rpt6 / 33105	FlyBaseID:	FBgn0020369	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_012820627.1	Gene:	atad2 / 100496913	XenbaseID:	XB-GENE-995542	Length:	1366	Species:	Xenopus tropicalis

Alignment Length:	373	Identity:	125/373 - (33%)
Similarity:	190/373 - (50%)	Gaps:	78/373 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 EKHQNLRRLQAQRNELNAK---VRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVD 97
            |:|.. |||...||:..::   :.:.|::|:.:|:            |:.|:       |..:.|
Frog   366 EQHFE-RRLNRSRNKAISRCLPLNLQRDDLKGIQK------------DRMKI-------GASLAD 410

  Fly    98 LDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKE 162
            :|                           |.::|..|           .:..||||.|.|..:||
Frog   411 VD---------------------------PMQIDATV-----------RFSSVGGLSKHISSLKE 437

  Fly   163 VIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECT-------FIRVSGSELVQ 220
            ::..|:.:||:|:...|..|:|.|.||||||||||:|||:|:  ||:       |....|::.:.
Frog   438 MVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALAN--ECSIGDRRVAFFMRKGADCLS 500

  Fly   221 KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEAT 285
            |::||..|.:|.||..|.:..|||||.||||.:...|........|.:..|:|.|   :||.::.
Frog   501 KWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGLDSR 562

  Fly   286 KNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN-LTRGINLRKIAEL 349
            ..|.||.||||:|.:||||.||||.||:..|..|::|||.||||||:::.| ....:.|.:::|.
Frog   563 GEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDQEARKDILKIHTKEWNPKPSDLFLDELSEK 627

  Fly   350 MPGASGAEVKGVCTEAGMYALRER--RVHVTQEDFEMAV--AKVMQKD 393
            ..|..||::|.||.||.:.:||.|  :::.|.|..::.|  .|:..||
Frog   628 CVGYCGADIKSVCAEAALCSLRRRYPQIYTTTEKLQLDVDSIKITAKD 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	RPT1	17..403	CDD:224143	125/373 (34%)
		SlyX	<27..>69	CDD:294687	10/35 (29%)
		AAA_16	152..>205	CDD:289934	28/52 (54%)
		AAA	185..317	CDD:278434	61/138 (44%)
atad2	XP_012820627.1	CDC48	<420..>692	CDD:273521	108/272 (40%)
		ycf46	<709..929	CDD:177094
		Bromo_AAA	981..1092	CDD:99957
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910