DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt6 and atad2b

DIOPT Version :9

Sequence 1:	NP_608447.1	Gene:	Rpt6 / 33105	FlyBaseID:	FBgn0020369	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_002936030.2	Gene:	atad2b / 100496692	XenbaseID:	XB-GENE-5956276	Length:	1413	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	106/272 - (38%)
Similarity:	160/272 - (58%)	Gaps:	23/272 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 VDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTG 194
            |||    |.:::  ...::.||||.:.|..:||::..|:.:||:|:...|..|:|.|.|||||||
Frog   358 VDP----MSLDR--SVRFDSVGGLSEHIYALKEMVVFPLLYPEIFEKFRIQPPRGCLFYGPPGTG 416

  Fly   195 KTLLARAVAHHTEC-------TFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDS 252
            |||:|||:|:  ||       :|....|::.:.|::||..|.:|.||..|....|||||.||||.
Frog   417 KTLVARALAN--ECSQGDKKVSFFMRKGADCLSKWVGESERQLRLLFDQAYVMRPSIIFFDEIDG 479

  Fly   253 IGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFP 317
            :...|........|.:..|:|.|   :||.:....|.||.||||:|.:||||.||||.||:..|.
Frog   480 LAPVRSSRQDQIHSSIVSTLLAL---MDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFS 541

  Fly   318 PPNEEARLDILKIHSRKMN--LTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER--RVHVT 378
            .|:::||..||:||:|..|  |:... |.::||...|..||::|.:||||.:.|||.|  :::.:
Frog   542 LPDQKARKHILQIHTRDWNPKLSDSF-LEELAEKCVGYCGADIKALCTEAALIALRRRYPQIYAS 605

  Fly   379 QEDFEMAVAKVM 390
            .:..::.::.|:
Frog   606 SQKLQLDISSVV 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6	NP_608447.1	RPT1	17..403	CDD:224143	106/272 (39%)
		SlyX	<27..>69	CDD:294687
		AAA_16	152..>205	CDD:289934	27/52 (52%)
		AAA	185..317	CDD:278434	61/138 (44%)
atad2b	XP_002936030.2	SpoVK	<316..598	CDD:223540	104/251 (41%)
		CDC48	<367..979	CDD:273521	102/257 (40%)
		Bromo_AAA	928..1039	CDD:99957
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910