DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1801 and proV

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	NP_417163.1	Gene:	proV / 947148	ECOCYCID:	EG10771	Length:	400	Species:	Escherichia coli

Alignment Length:	410	Identity:	94/410 - (22%)
Similarity:	156/410 - (38%)	Gaps:	91/410 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 LKNISMRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPNGEA------RRLV 575
            :|:.|:.|..||:|||:|..||||.|::|:|..|..|.||.|.|.|.......:|      |:.:
E. coli    44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKI 108

  Fly   576 DFRFDEHGLNKHLTVEQTIDYHVRLKLSPSESDRYEIERRKWLAILDQHVESRGVRIG------- 633
            ...|....|..|:||.....:.:.|....:|.     .|.|.|..|.|        :|
E. coli   109 AMVFQSFALMPHMTVLDNTAFGMELAGINAEE-----RREKALDALRQ--------VGLENYAHS 160

  Fly   634 ---KLSSGSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAE----------KENRA 685
               :||.|..:.|.|...||.:..|::::|..:.|.        .::..|          |..|.
E. coli   161 YPDELSGGMRQRVGLARALAINPDILLMDEAFSALD--------PLIRTEMQDELVKLQAKHQRT 217

  Fly   686 FIIATYNVGEAEHVADRIGILSMGVLEASGTPFFLRSKFSSSVDLVIIKKPHVPDQPITDYINQF 750
            .:..::::.||..:.|||.|:..|.:...|||                  ..:.:.|..||:..|
E. coli   218 IVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP------------------DEILNNPANDYVRTF 264

  Fly   751 MQNIEPENEIG---------DSLTYRLPVIYRPRLQKLLIHLEIDRKMLGI--ENVRVVGAELSD 804
            .:.::......         :.|..:.|. :.||....|:..| ||:...:  ...:.|||...|
E. coli   265 FRGVDISQVFSAKDIARRTPNGLIRKTPG-FGPRSALKLLQDE-DREYGYVIERGNKFVGAVSID 327

  Fly   805 IYMTLVTSFRLQQQMIPDVTQTFKYQVVSQKQLTKQRMRAMFYKKMIHTAPNVWPIIMIFTSFVL 869
            ...|.:|    |||.:..........|.:|..|::       ....:..||...|::.....:|
E. coli   328 SLKTALT----QQQGLDAALIDAPLAVDAQTPLSE-------LLSHVGQAPCAVPVVDEDQQYV- 380

  Fly   870 IAIIARLSVLLDMPKERQNS 889
             .||::..:|..:.:|..|:
E. coli   381 -GIISKGMLLRALDREGVNN 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047	59/225 (26%)
		P-loop_NTPase	500..721	CDD:304359	61/229 (27%)
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047
		P-loop_NTPase	1324..1524	CDD:304359
proV	NP_417163.1	PRK10070	1..400	CDD:182221	94/410 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14986
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	2	2.000