DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1801 and RLI1

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	NP_010376.3	Gene:	RLI1 / 851665	SGDID:	S000002498	Length:	608	Species:	Saccharomyces cerevisiae

Alignment Length:	392	Identity:	89/392 - (22%)
Similarity:	146/392 - (37%)	Gaps:	113/392 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   438 SALIYFLILLAIQWRMPGTFLSRRIVNNRPRKQQESDTTIMYLGRAPSFQNFEFGDVGSVELMRL 502
            |.|.|....:.|.:.:|..:    .|...|...:|. ..|...|..|: :|..|    ..|.::.
Yeast   282 SVLDYLSDFVCIIYGVPSVY----GVVTLPASVREG-INIFLDGHIPA-ENLRF----RTEALQF 336

  Fly   503 RHVSTS---HRDSERKILKNISMRIYRG--------------EVFVILGHIGSGKLTLLRILAGL 550
            |....:   ..||..:.....|::..:|              |:.|::|..|:||.||:::|||.
Yeast   337 RIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAGA 401

  Fly   551 KFPLRG------NVYIMGNPFEPN--GEARRLVDFRFDEHGLNKHLTVEQTIDYHVRLKLSPSES 607
            ..|..|      ||.:......|.  |..|:|...:.....||.....:         .:.|...
Yeast   402 LKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTD---------VVKPLRI 457

  Fly   608 DRYEIERRKWLAILDQHVESRGVRIGKLSSGSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQI 672
            |          .|:||.|:       .||.|.::.||:...|.....|.:::||:..|.. |.:|
Yeast   458 D----------DIIDQEVQ-------HLSGGELQRVAIVLALGIPADIYLIDEPSAYLDS-EQRI 504

  Fly   673 FWS------IVHAEKE----NRAFIIATYNVGEAEHVADRIGILSMGVLEASGTPFFLRSKFSSS 727
            ..|      |:|.:|.    ...||:|||       :||:       |:...|.|
Yeast   505 ICSKVIRRFILHNKKTAFIVEHDFIMATY-------LADK-------VIVFEGIP---------- 545

  Fly   728 VDLVIIKKPH--VPDQPITDYINQFMQNIEPENEIGDSLTYRL-PVIYRPRLQKLLIHLEIDRKM 789
                 .|..|  .|:..:|. .|:|::|:        ::|:|. |..:|||:.||...::.::|.
Yeast   546 -----SKNAHARAPESLLTG-CNRFLKNL--------NVTFRRDPNSFRPRINKLDSQMDKEQKS 596

  Fly   790 LG 791
            .|
Yeast   597 SG 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500	3/9 (33%)
		EcfA2	499..717	CDD:224047	57/252 (23%)
		P-loop_NTPase	500..721	CDD:304359	58/255 (23%)
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047
		P-loop_NTPase	1324..1524	CDD:304359
RLI1	NP_010376.3	Rli1	4..603	CDD:224166	89/392 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910