DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1801 and GCN20

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	NP_116664.1	Gene:	GCN20 / 850561	SGDID:	S000001905	Length:	752	Species:	Saccharomyces cerevisiae

Alignment Length:	290	Identity:	69/290 - (23%)
Similarity:	124/290 - (42%)	Gaps:	49/290 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 KQQESDTTIMYLGRAPSFQ--------NFEFG--DVGSVELMRLRHVSTSHRDSERKILKNISMR 523
            |.||:.:.|..|.:.|..:        :|:|.  |..|..:::|:.||..: |....:||::::.
Yeast   491 KSQEAQSRIKKLEKLPVLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGY-DENNLLLKDVNLD 554

  Fly   524 IYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPNGEARRLVDFRFDEHGLNKHL 588
            :.......::|..|.||.|||:|:.....||:|  ::..||        ||....|.:|.::...
Yeast   555 VQMDSRIALVGANGCGKTTLLKIMMEQLRPLKG--FVSRNP--------RLRIGYFTQHHVDSMD 609

  Fly   589 TVEQTIDYHVRLKLSPSESDRYEIERRKWLAILDQHVESRGV-------RIGKLSSGSMKLVALC 646
            .....:|:  ..|..|.::|.   |.|:       |:.|.|:       ::..||.|....||..
Yeast   610 LTTSAVDW--MSKSFPGKTDE---EYRR-------HLGSFGITGTLGLQKMQLLSGGQKSRVAFA 662

  Fly   647 CCLAGDTPIIILEEPTTQL--TGREAQIFWSIVHAEKE-NRAFIIATYNVGEAEHVADRIGILSM 708
            .....:..|::|:||:..|  ||.:|     :|.|.|. |...::.::::...:.|...|.:...
Yeast   663 ALCLNNPHILVLDEPSNHLDTTGLDA-----LVEALKNFNGGVLMVSHDISVIDSVCKEIWVSEQ 722

  Fly   709 GVLEA-SGTPFFLRSKFSSSVDLVIIKKPH 737
            |.::. .||.:..|.....|.|...:.|.|
Yeast   723 GTVKRFEGTIYDYRDYILQSADAAGVVKKH 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047	53/228 (23%)
		P-loop_NTPase	500..721	CDD:304359	54/231 (23%)
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047
		P-loop_NTPase	1324..1524	CDD:304359
GCN20	NP_116664.1	PLN03073	<190..742	CDD:215558	65/278 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910