DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1801 and ABCG23

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	NP_197442.2	Gene:	ABCG23 / 832061	AraportID:	AT5G19410	Length:	633	Species:	Arabidopsis thaliana

Alignment Length:	843	Identity:	165/843 - (19%)
Similarity:	296/843 - (35%)	Gaps:	281/843 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 QESDTTIMY-LGRAP-----SFQNFEFGDVGSVELMRLRHVSTSHRDSERKILKNISMRIYRGEV 529
            :|.|:.|:: ...:|     :..:|....:.:.....|...:.|:..:...||.::|:.....::
plant    24 REEDSIILFSASNSPDEFSSASSSFSSSPLPTPNRYSLTVTNLSYTINHTPILNSVSLAAESSKI 88

  Fly   530 FVILGHIGSGKLTLLRILAGLKFPLRGN--------VYIMGN-PFEPNGEARRLVDFRFDEHGLN 585
            ..::|..|:||.|||:|::|     |.|        ..:|.| ......:.|||..|...:..|.
plant    89 LAVVGPSGTGKSTLLKIISG-----RVNHKALDPSSAVLMNNRKITDYNQLRRLCGFVPQDDDLL 148

  Fly   586 KHLTVEQTIDYHVRLKLSPSESDRYEIERRKWL-------AILDQHV-----ESRGVRIGKLSSG 638
            ..|||::|:.|..:..|..|.:...| ||.:.|       .:.|..|     |.|||     |.|
plant   149 PLLTVKETLMYSAKFSLRDSTAKERE-ERVESLLSDLGLVLVQDSFVGEGDEEDRGV-----SGG 207

  Fly   639 SMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEAEHVADRI 703
            ..|.|::...:..|.||::|:|||:.|..|.
plant   208 ERKRVSIAVEMIRDPPILLLDEPTSGLDSRN---------------------------------- 238

  Fly   704 GILSMGVLEASGTPFFLRSKFSSSVDLVIIKKPHVPDQPITDYINQFMQNIEPENEIGDSLTYRL 768
               |:.|:|       |.:..:.|....::...|.|...|.|||:.::            :..|.
plant   239 ---SLQVVE-------LLATMAKSKQRTVLFSIHQPSYRILDYISDYL------------ILSRG 281

  Fly   769 PVIYRPRLQKLLIHLEIDRKMLGIENVRVVGAELSDI--YMTLVTSFRLQQQMIPDVTQTFKYQV 831
            .||:...|:    |||.....||.:    :..:|:.|  .|.:|.|.|           |||...
plant   282 SVIHLGSLE----HLEDSIAKLGFQ----IPEQLNPIEFAMEIVESLR-----------TFKPNS 327

  Fly   832 VSQKQLTKQRMRAMFYKKMIHTAPNVWPIIMIFTSFVLIAIIARLSVLLDMPKERQNSIHIGFRE 896
            |:                 :..:.::||                           :|:.:.|...
plant   328 VA-----------------VVESSSMWP---------------------------ENNENDGIIS 348

  Fly   897 PEDVVKYLPNLKDCGYIDIRSAVKVNKKKSVGVSRTFDDDSFVCEKGSYRNNLRKKNELRSFGAV 961
            .::..:.| ::.:..|:..|....:.:.|.:.::||..........||....|::..|    |..
plant   349 KKEAFRVL-DVTEISYLCSRFCKIIYRTKQLFLARTMQAVVAGLGLGSVYTRLKRDEE----GVA 408

  Fly   962 ESDGDEHLNGYISQDMFHSAPMMLNLLQNVILRLSYPMQTDLVVLVENHPLPTQLSQKIN--VLD 1024
            |..|           :|  |..:..||.:.:..|...::...|::.|:    ::.|.:|:  ::.
plant   409 ERLG-----------LF--AFSLSFLLSSTVEALPIYLRERRVLMKES----SRGSYRISSYMIA 456

  Fly  1025 NKIAHIHVPLVVGCIIPLTVSVFVIPLVEEEIYDVRFLQHMAGLGLKVFW--GINLFWDWFTFFV 1087
            |.||.:....||..:       |.||                     |:|  |:|.....|:|||
plant   457 NTIAFVPFLFVVSLL-------FSIP---------------------VYWIVGLNPSIQAFSFFV 493

  Fly  1088 YSVIIVVIMS------LMGIGGFGFYENAIMVVLLTTFGLAA--------LPLTYLVSMFVNKSI 1138
            ..|.::::|:      |..:.......|:::..:|..|.|.:        :|..::...:|  |:
plant   494 LCVWLIILMASSLVLFLSAVSPDFISGNSLICTVLGAFFLFSGYFIPKEKIPKPWMFMYYV--SL 556

  Fly  1139 VRAFLVSVLLQGVSGLVLYIIYWDVANSNTIFFYAACMSPGFSLLDGVSNVYAQNLEQAICIDKC 1203
            .|..|.|:::..         ||.:...        |.|.|             |:.   |:...
plant   557 YRYPLESMVVNE---------YWSMREE--------CFSSG-------------NMG---CLMTG 588

  Fly  1204 EATDSCTEENMNEVVPNCKFDTFFKWAAPGILPPILYMVLSALIFLMLIFW-IELHRREKKFH 1265
            |  |...|..:::       ||  :|...||:       |:..:|..::.| |.|.:..|..|
plant   589 E--DVLKERGLDK-------DT--RWINVGIM-------LAFFVFYRILCWGILLRKASKSTH 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047	56/238 (24%)
		P-loop_NTPase	500..721	CDD:304359	56/241 (23%)
		ABC2_membrane_3	<972..1254	CDD:289468	55/299 (18%)
		EcfA2	1307..1521	CDD:224047
		P-loop_NTPase	1324..1524	CDD:304359
ABCG23	NP_197442.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910