DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1801 and pak1ip1

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	NP_001017054.2	Gene:	pak1ip1 / 549808	XenbaseID:	XB-GENE-492186	Length:	365	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	52/276 - (18%)
Similarity:	98/276 - (35%)	Gaps:	64/276 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1351 LVGQRGFAFGEIYVRGLDFKYDL---------------------ESIHTY-MGYSPQHRGLLNE- 1392
            |.|.|....||.::...||.:..                     |:|..| |....:|..||:.
Frog    16 LFGYRVHREGEQWLSSADFTHHAHTASLSVVAVNNRFVATGSKDETIQIYDMKKKVEHGALLHHN 80

  Fly  1393 --LTPREHIRLLCMIRGVPEAKIGEKMHDLCLMLNMTGWMHRKCSLLTAEKRHKLKI-ALALVAY 1454
              :|..:......::.|..:..|       |:      |..:|.......|.||.:: :|::...
Frog    81 GTITCLQFYGNTHLLSGAEDGLI-------CV------WNTKKWECQQTFKAHKGQVLSLSIHPS 132

  Fly  1455 NKILVLDEPTCGMPATTRREIWNI-------LRYIRYCGKTIIFATNDELECKILADFIILFQDS 1512
            .|:.:    :.|...|.|  .||:       ::.|:.....:.::.:.:....::.|.:.::|..
Frog   133 GKLAL----SVGTDKTLR--TWNLVEGRSAFIKNIKKNAHIVQWSPSGDKYVVVIHDKVDVYQLE 191

  Fly  1513 EMLAIGSLQYLRYKYSHGFYLEVRLIRDG-ATLAESEENLR-KDVENLAKFVNFLHNRSELVGRL 1575
            ....||::...:...|      |:.|.|. ..:|..||.:| .|..:......|..:.:    |:
Frog   192 TAAVIGTINNPKRISS------VQFITDALIAVAGDEEVIRLYDTASQKCVCEFKAHEN----RV 246

  Fly  1576 NNWFKFYVPVGHIVYS 1591
            .|...|.:...|||.|
Frog   247 KNLHVFELEETHIVVS 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047
		P-loop_NTPase	500..721	CDD:304359
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047	35/202 (17%)
		P-loop_NTPase	1324..1524	CDD:304359	35/205 (17%)
pak1ip1	NP_001017054.2	WD40	<35..294	CDD:225201	45/257 (18%)
		WD40	39..272	CDD:238121	45/253 (18%)
		WD40 repeat	43..78	CDD:293791	6/34 (18%)
		WD40 repeat	84..119	CDD:293791	6/47 (13%)
		WD40 repeat	124..160	CDD:293791	7/41 (17%)
		WD40 repeat	168..200	CDD:293791	4/31 (13%)
		WD40 repeat	205..240	CDD:293791	9/40 (23%)
		WD40 repeat	248..288	CDD:293791	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000