Protein Alignment CG1801 and abca8

DIOPT Version :9

• Sequence 1: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_031749971.1
• Gene: abca8 / 549630
• XenbaseID: XB-GENE-1005441
• Length: 1619
• Species: Xenopus tropicalis
• Alignment Length: 1825
• Identity: 371/1825 - (20%)
• Similarity: 706/1825 - (38%)
• Gaps: 417/1825 - (22%)

  Fly     5 KGLLFKRYIRIELNLWRR---TLFE---IVALVIMVLVIFLNPIAHSKRLLYTTTENENEQSIVS 63
            |.||.|         |||   |:.|   .:|.|:::|:|.:..::...:|.|      |..:.|.
 Frog    20 KNLLLK---------WRRKWHTILEWLQNLAFVLVMLLISVMGLSTFVQLEY------NSPAEVL 69

  Fly    64 HKLQDINILTRMADSKREKTKYILAFTPETTFTSEVTKNVAKTLELSSTVGYESESEMQNQFDER 128
            .:|..::      .|...|..|:  :|..|  :.::.:.|||::.:.. :..:..|:..|..|:.
 Frog    70 GRLDAVD------RSNNFKVGYV--YTSPT--SRDIMEKVAKSIIIPG-IKVQEYSDEGNLLDDM 123

  Fly   129 TTLA--GIVFNDLRDDGTPLTLSISIRFPSEFRTIAPFLTEDRLWITRCSGRINPGRDRAKHDKQ 191
            |..|  |:.|.|        ..|..||:|  ...|| :..:...::..|:    ||....    .
 Frog   124 TNKAVVGVTFVD--------KFSYHIRYP--INNIA-YPNDYFAFMGFCA----PGSQAC----Y 169

  Fly   192 QDIYIREGFLQLQHQIFVEWYHQLRKDIVSTYPEPNVEVYNILLKAADEPCSVMSVAQLPT---- 252
            ...|....||.||..|          |........|..|:       |...||::|....|
 Frog   170 PTYYWSRQFLSLQASI----------DSAIIELTSNHSVW-------DNMASVVTVRMKSTVASF 217

  Fly   253 ----FLYNFIYLLPF----------LNIIRNVAAQVEDGVMVHQWHYGYSFGMQWGIKFLVLFLR 303
                .:..||:|:|.          |.|.|......|...|:..  ...:|.:.||:.:|...|
 Frog   218 RQYFHIGTFIFLMPMCYVSLMYLLSLYITRERREMRELLKMMRL--KDLAFWLSWGLLYLFYIL- 279

  Fly   304 MCILGVIYTIMLLAFWGFGGREGEF--SGTGTIAFVCFITLYTVEIIITGMVVAKLFANPTNAVL 366
              ||..:.|::..||        .|  |..|.|.|:  ...|.:.::....:::.||.:|....:
 Frog   280 --ILANLMTLVTKAF--------VFVQSSYGIIMFL--FVFYGIALMSFTFMLSALFRSPRATAI 332

  Fly   367 FALMLWLFMYAAFCIILERYWDIHKYYVFFILVAFCNCQMHFSMSLFRNCIEKPEMVNTIDFVL- 430
            ....:.||:.|...::|.:.:......:..|...|.     |::.|    .|...|.:.:..|.
 Frog   333 AGFFITLFLSALGLVLLRKDFPQALAVLLSIFPQFA-----FAVGL----TESVHMESDLQGVYF 388

  Fly   431 ---------IFTSAISSAL---------IYFLILLAIQ--------WRMPGTFLSRRIVNNRPRK 469
                     :.:|.||.||         :||..:||.:        :.|..::.|::.::....:
 Frog   389 SDMAGDSSHVLSSFISLALDSIFYMGLTLYFEKVLADKHGLKYEPFFFMKSSYWSKKKLSPVLTQ 453

  Fly   470 QQESDTTIM--YLGRAPSFQNFEFGDVGSVELMRLRHVSTSHRDSERKI--LKNISMRIYRGEVF 530
            .::|..:.|  :..|.|.       |:...|.:|:..|...:.|.::.|  |:.:.:.||.|::.
 Frog   454 TEDSGESSMGEFFERVPI-------DLHGKEAIRINKVMKKYCDQDKNIEALRGLDLNIYEGQIT 511

  Fly   531 VILGHIGSGKLTLLRILAGLKFPLRGNVYIMG---NPFEPNGEARRLV------DFRFDEHGLNK 586
            .:|||.|:||.|||.||:||.....|:..:..   :..:...|.::..      |.:|:.
 Frog   512 ALLGHSGAGKTTLLNILSGLCPASDGSATVYSYKLSDMQHLEEIKKRTGFCPQSDVKFNP----- 571

  Fly   587 HLTVEQTIDYHVRLKLSPSESDRYEIERRKWLAILDQHVESRGVRIGKLSSGSMKLVALCCCLAG 651
             |||::.:....::|..|.:..:::::  |.|:.|..: :...|....||.|..:.:.|...|.|
 Frog   572 -LTVKENLTVFAKIKGIPRKQIKHKVQ--KVLSDLQMN-DIENVEADNLSGGQRRKLTLGIALLG 632

  Fly   652 DTPIIILEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEAEHVADRIGILSMGVLEASGT 716
            |..:::|:|||..|........|:|:...|.:|..:.:|..:.||:.:|||..::|.|.|:..|:
 Frog   633 DPQVLLLDEPTAGLDPCSRHHIWTILKENKADRVTLFSTQFMDEADILADRKAVISNGRLKCVGS 697

  Fly   717 PFFLRSKF------------SSSVDLVI-IKKPHVPDQPITDYINQFMQNIEPENEIGDSLTYRL 768
            ..||:.|:            :..|:|:. |.|.||||..:|           .:||  :.|||.|
 Frog   698 SLFLKRKWGIGYHLRMQVSPTCDVELMTSIIKQHVPDAKLT-----------AQNE--EELTYTL 749

  Fly   769 PVIYRPRLQKLLIHLEIDRKMLG--IENVRVVGAELSDIYMTLVTSFRLQQ---------QMIPD 822
            |.........|.:||:   ..:|  |.|..|....|.|:::.|.....:::         ...|:
 Frog   750 PFENMDAFPDLFLHLD---GQVGNSIVNYGVSMTTLDDVFLKLEGEGEIEKGDYGVFSPDSGAPE 811

  Fly   823 VTQTFK--------------------YQVVSQKQLTKQRMRAMFYKKMIHTAPNVWPIIMIFTSF 867
            ....|.                    ..:..|:.|...|:|.:   |:.|.:.....|:::...|
 Frog   812 DKDCFSAGMEDSLLLMSDSGSATLSGLSLWRQQVLAIARVRLL---KLKHDSKTFRSILILLALF 873

  Fly   868 VLIAIIARLSVLLDMPK----ERQNSIHIGFREPED-VVKYLPNLKDCGYIDIRSAVK----VNK 923
            : |.||....|:....|    |...|::  |:.||| ..:|..:|:.  |.:..|:::    ..|
 Frog   874 I-IPIIMTTIVIKIFHKVITWELTPSLY--FQHPEDRFHRYYTDLQI--YNNTGSSIEDFLGALK 933

  Fly   924 KKSVGVSRTFDDDSFVCEKGSYRNNLRKKNELRSFGAVESDGDEHLNGYISQDMFHSAPMMLNLL 988
            ::::.|...  :..:..|...||..:......:.:|.......:..|         :.|:::|::
 Frog   934 EQNIAVQVV--NGEYDMETTFYRGAIEVSQATKGYGFTIVGNPKAQN---------ALPVLVNII 987

  Fly   989 QNVILRLSYPMQTDLVVLVENHPLPTQLSQKINVLDNKIAHIHVPLVVGCIIPLTVS----VFVI 1049
            .|.:|.:   ..:...:.|.|||:...|.:...         .|....|.::.|..|    .|.:
 Frog   988 SNALLMI---FNSTEHIRVWNHPVTEYLVEDFE---------SVTFYSGFMLLLFASGLAPHFAM 1040

  Fly  1050 PLVEEEIYDVRFLQHMAGLGLKVFW------GINLFWDWFTFFVYSVIIVVIMSLMGIGGFGFYE 1108
            ..:|:.....|....::|:....:|      .:.|:|     .:..:::.::.|......|.|..
 Frog  1041 SSIEDRRIKARTQLRISGIFPSAYWFGQALVDVPLYW-----ILLFLMVAILFSFNSQVIFSFVP 1100

  Fly  1109 NAIMVVLLTTFGLAALPLTYLVSMFVNKS-----------IVRAFLVSVLLQGVSGLVLYIIYWD 1162
            ..|::..:..:|.|.:...|::|....:.           ::.||:..:||..||...:.|.::.
 Frog  1101 AIILITGVIGYGAAVVLYVYVISFVFGRGKSHHDGWSIFFVISAFIPMILLDVVSTYAVGITFFL 1165

  Fly  1163 VANSNTIFFYAACMSPGFSLLDGVSNVYAQNLEQAICIDKCEATDSCTEENMNEVVPNCKFDTFF 1227
            :..::|              |.|:..          |||......|..|:..       ....||
 Frog  1166 LLPAST--------------LSGIIR----------CIDVYHFDRSTLEDEH-------LLYLFF 1199

  Fly  1228 KWAAPGILPPILYMVLSALIFLMLIFWIELHR-------REKKFHTSRDLRKMRTATYPFDDGDV 1285
                     |.|::|:     ..:|.|: |.|       :...|:..:..:.........|:..:
 Frog  1200 ---------PFLHIVI-----FSVILWV-LERVFGMRSLKTNLFYRKKVQKNQEELGEDTDEEVL 1249

  Fly  1286 ADVKQ-KIAEADNTKAKQSVFLVDQV--EARV-----------PAAGKRIHTVSFALNKYMSMGI 1336
            |:.:: |::...|...::.:.:||.:  |.:|           .||.|.|   ||.:.|...:|:
 Frog  1250 AERERVKMSSTTNNMEEKPIIIVDSLRKEYKVKKGKSFFKKNKKAATKNI---SFCVRKGEVLGL 1311

  Fly  1337 FGPRNSGKSHLMRQLVGQRGFAFGEIYVRGLD------FKYDLESIHTYMGYSPQHRGLLNELTP 1395
            .||..:||:..:..|.|:.....||:.:.|.|      .:||...   .:||.||...|...||.
 Frog  1312 LGPNGAGKTTSIYMLAGEIRPTAGEVLLCGTDPDKSQNSQYDPTG---SLGYCPQDNPLWPNLTV 1373

  Fly  1396 REHIRLLCMIRGVPEAKIGEKMHDLCLMLNMTGWMHRKCSLLTAEKRHKLKIALALVAYNKILVL 1460
            ::|:.:...::|:.:......:..:...|.:...:.:....|:|....|:..|::::....|::|
 Frog  1374 KQHLEIYAAVKGLKKKDAETAIKRVSEALELKEHLEKAARKLSAGVSRKVCFAISMLGNPNIVLL 1438

  Fly  1461 DEPTCGMPATTRREIWNILR-YIRYCGKTIIFATNDELECKILADFIILFQDSEMLAIGSLQYLR 1524
            |||:.|:....::.:|..:| ..|...:..|..|:...|.:.:.|.:.:....::..|||:|.|:
 Frog  1439 DEPSTGLDPKGQQRLWRAIRSAFRNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLK 1503

  Fly  1525 YKYSHGFYLEVRLIRDGATLAESEENLRKDVENLAKFVNFLHNRSELV---------GRLNNWFK 1580
            .|:..|:.||::                  |:| :..|:.:||  |::         .|.::...
 Frog  1504 SKFGKGYLLEIK------------------VKN-SNQVDQIHN--EIIQIFPHAARQDRFSSLLV 1547

  Fly  1581 FYVPVGHI-VYSFLYGAMEKNKLRLNVSDYCIYQADMMSVVAQVQETRA----------QLKHHL 1634
            :.:||.:: ..|..:..:|:.|...|:.:|...|..:..|..::.:.:.          |.|...
 Frog  1548 YKIPVENVQSLSKAFLDLEEAKRAYNIEEYSFSQPTLTQVFIELTKEQEREDFDSASTFQWKQLR 1612

  Fly  1635 VQTEG 1639
            .::||
 Frog  1613 TESEG 1617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	33/152 (22%)
		ABC2_membrane_4	<293..448	CDD:289500	36/175 (21%)
		EcfA2	499..717	CDD:224047	60/228 (26%)
		P-loop_NTPase	500..721	CDD:304359	61/231 (26%)
		ABC2_membrane_3	<972..1254	CDD:289468	49/302 (16%)
		EcfA2	1307..1521	CDD:224047	54/233 (23%)
		P-loop_NTPase	1324..1524	CDD:304359	47/206 (23%)
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	310/1540 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010