Protein Alignment CG1801 and CG42816

DIOPT Version :9

• Sequence 1: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Alignment Length: 1609
• Identity: 324/1609 - (20%)
• Similarity: 634/1609 - (39%)
• Gaps: 324/1609 - (20%)

  Fly   189 DKQQDIYIREGFLQLQH---QIFVEW----YHQLRKDI----VSTYPEPNVEVYNILLKAADEPC 242
            |....:| :.|||.:|.   |:.::.    :::.:.||    :...|.|.:       ..:|...
  Fly     5 DGSYPLY-KTGFLAVQQALSQVHIKHKCKEFNKTQGDIKFPPIKDLPSPPI-------FKSDNSS 61

  Fly   243 SVMSVAQLPTFLYNFIYLLPFLNIIRNVAAQVED------------GV-MVHQWHYGYSFGMQWG 294
            ::..|..:      .|.::.|..::....:.||:            || ...||       :.|.
  Fly    62 TLQDVGIM------IIVIIIFFVVVSLTKSIVEEKELQLKVTLNLMGVGSCLQW-------VAWY 113

  Fly   295 IKFLVLFLRMCILGVIYTIMLLAFWGFGGREGEFSGTGTIAFVCF----ITLYTVEI-----IIT 350
            |:..::||       |.:.::..||.......|      |:|:.|    :.|:.:.:     |..
  Fly   114 IQTFIIFL-------IGSSIITLFWKLVLPNSE------ISFMPFTHWSMALFVLLVLSHCTICF 165

  Fly   351 GMVVAKLFANPTNAVLFALMLWLFMYAAFCIILERYWD--IHKYYVFFIL-------VAFCNCQM 406
            ..:::.|.:......|...:..:..|..|.|:..:...  ::.:...|:|       |..|..:.
  Fly   166 SFLMSSLISTTYRISLVTFLALIATYLPFLILHSKGCSEGLNVFLSLFLLSGLQVLVVGICMWED 230

  Fly   407 HFSMSLFRNCIEKPEMVNTIDFVLIFTSAISSALIYFLILLAIQWRMPGTF-------------- 457
            :.....:.|..|......|:....|....|.::.:..|:.|.::...||.:
  Fly   231 YGEGLQWGNLFETSWPGGTLSVGYILLVMILASFLSLLLCLYLEKIRPGPYGVPQPWHFPCTRCC 295

  Fly   458 ----------LSRRIVNNRPRKQQESDTTIMYLGRAPSFQNFEFGDVGSVELMRLRHVSTSHRDS 512
                      |..||.........|         ..|..|..|...|..:..:::|.:|.:.  .
  Fly   296 STESLLPYSRLFNRIFGIYSAAPDE---------ERPDLQLIEPDPVDKIAGVQIRGLSKTF--G 349

  Fly   513 ERKILKNISMRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPF-EPNGEARRLVD 576
            :.:::||:|..::.|::.|::||.|:||.||:.:|||...|..|...|.|... :...:|:|.:.
  Fly   350 KMEVVKNVSFDMFEGQITVLMGHNGAGKTTLISMLAGFISPTSGTALINGFDIRQERRQAQRCIG 414

  Fly   577 FRFDEHGLNKHLTVEQTIDYHVRLKLSPSESDRYEIERRKWLAILDQHVESRGVRIGKLSSGSMK 641
            ....::.|.|||:....|....||:.......:.|::  .:|..|:.. |.:.:....||.|:.:
  Fly   415 LCPQQNVLFKHLSSVSHIQLFSRLRGLRGAEVKSEVQ--NYLKKLNLQ-EKKRLAARNLSGGTQR 476

  Fly   642 LVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEAEHVADRIGIL 706
            .:::.|.|.|...::|.:||:|.|.....:..|.::...||....::.|:.:.:.|.:.||:.|:
  Fly   477 RLSVACSLCGGVKVLICDEPSTGLDPSARRELWRLILEAKEGCTILLTTHQLDDGEVLGDRVVII 541

  Fly   707 SMGVLEASGTPFFLRSKFSSSVDLVIIKKPHVPDQPITDYINQFMQNIEPENEIGDSLTYRLPVI 771
            |.|.|...|:..||:.:..:|..:....:.....:.:|..|::.:..|:|.:..|..:.|:||:.
  Fly   542 SDGQLRCIGSLPFLKKQVDASCLITCEARKRCDLEKLTSLISRHVGTIQPFSIKGRDVCYKLPLS 606

  Fly   772 YRPRLQKLLIHLEIDRKMLGIENVRVVGAELSDIYMTLVTSFRLQ----------QQMIPDVTQT 826
            .......|...||....:||:....:....|.:|:|    ||..:          ::...|....
  Fly   607 KSKYFSSLFRDLESQMNILGVRGFSLSSVSLEEIFM----SFGAEDLNSRQSGGAEKRDDDDRDD 667

  Fly   827 FKYQVVSQKQL--TKQRMRAMFYKKMIHTAPN--------VWPIIMIFTSFVLIAI--------- 872
            .:...|....:  .|::.|||..||::....|        :.||:...|:.::...
  Fly   668 DEENEVQDGNVRSCKKQWRAMMTKKVMALYDNKVYFLLLLLTPIVYYITTLMMATKPHHSGRPTF 732

  Fly   873 ------IARLSVLLDMP------KERQNSIHIGFREPEDVVKYLPNLKDCGYIDIRSAVKVNKKK 925
                  :.:.::||.:|      :||:..                        .|.|.:| .|.|
  Fly   733 NISDYGVDKFTILLSVPVSKSYTEERRAD------------------------SIASLIK-GKLK 772

  Fly   926 SVGVSRTFDDDSFVCEKGSYRNNLRKKNELRSFGAVESDGDEHLNGYIS-QDMFHSAPMMLNLLQ 989
            .:.||....|  :|.:|...|...|:.|.:..  |:::.....|.|::. :...|:|||:|||:.
  Fly   773 LIVVSEQIKD--YVDDKWKSREGRREINFVSM--AIDTGDRTGLIGWVGPRHYVHAAPMILNLVY 833

  Fly   990 NVILRLSYPMQTDLV---VLVENHPLPTQLSQKINVLDNKIAHIHVPLVVGCIIPLTVSVFVIPL 1051
            |.:.:       :|:   :.:|...:|..|.:|.:.|.:....|  |:.|...:.:.:.:|...:
  Fly   834 NALAQ-------ELIGPKISIEVTSVPFTLRKKEDFLISNNGDI--PIYVIGYVSIAMIIFSSAV 889

  Fly  1052 VEEEIYDVRFLQHMAGLGLKVFWGINLFWDWFTFFVYSVIIVVIMSLMGIGGFGFYENAIMVVLL 1116
            ::|.:..::.||.::||.:..:|..:|.:|...||:  :::.:::.|     :|:....:::.:|
  Fly   890 IQERVSHMKMLQEVSGLEMITYWLSHLAFDMVVFFI--LVLALLLPL-----YGYAPWYLLLCVL 947

  Fly  1117 TTFGLAALPLTYL-----------VSMFVNKSIVRAFLVSVLLQGVSGLVLYIIYWDVANSNTIF 1170
            ...|||.|...|.           |||.:...|:.:.::.:|  |...|:..::|        :.
  Fly   948 FFTGLAGLIFIYFLISMLSATFLAVSMILLSVIIGSLILMIL--GALALIFKMVY--------VA 1002

  Fly  1171 FYAACMSPGFSLLDGVSNVYAQNLEQAICIDKC------------EATDSCTEENMNE------- 1216
            .|.|.|.|   |:.|.:           ||.||            ||.:..:|...::
  Fly  1003 IYVANMHP---LIAGYN-----------CIQKCFHYMSLCGSYISEAQNPLSENLTSDEMYCINP 1053

  Fly  1217 ---VVPNCKFDTFFKWAAPGILPPILYMVLSALIFLMLIFWIE----LHRREKKFHTSRDLRKMR 1274
               :.|.|.......|      |.:|.|:.:|:|..:||.:.|    :..|.|
  Fly  1054 LAFLEPRCVCVNPMTW------PDMLVMLGTAIILFLLIMFFEYGSCVWYRCK------------ 1100

  Fly  1275 TATYPFDD-GDVADVK-----QKIAEADNTKAKQSVFLVDQVEARVPAAGKRIHTVSFALNKYMS 1333
             ...|:.. |.:.|.|     :||...|..:......:|:.|..:.......::.:||||.....
  Fly  1101 -GCCPYSSKGSIEDPKVSREAEKIRAMDADQIGTRALVVNGVSKKYGCDQLAVNNISFALKPSHC 1164

  Fly  1334 MGIFGPRNSGKSHLMRQLVGQRGFAFGEIYVRGLDFKYDLESIHTYMGYSPQHRGLLNELTPREH 1398
            :|:.||..:||:...:.:||:.....|.||:.|...:.........:||.||.......||.|:.
  Fly  1165 VGLLGPNGAGKTTTFKMIVGEHSIDKGNIYISGYSMRMKRNKAMKELGYCPQSDSFFEFLTGRQL 1229

  Fly  1399 IRLLCMIRGVPEAKIGEKMHDLCLMLNMTGWMHRKCSLLTAEKRHKLKIALALVAYNKILVLDEP 1463
            :::..:|.|.|...:.::...|.........:.:|.:..:...:.|:..|:|..| |.::.||||
  Fly  1230 LKVFLLIWGFPSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVACGA-NSLICLDEP 1293

  Fly  1464 TCGMPATTRREIWNILRYIRYCGKTIIFATNDELECKILADFIILFQDSEMLAIGSLQYLRYKYS 1528
            :.|:...:||.:|.|:..:...||.::..:::..|...|....::..|..:.|:||:|:::.|.:
  Fly  1294 SAGVDPASRRHVWTIINEVAQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIA 1358

  Fly  1529 HGFYLE--VRLIRDG--ATLAESEENLRKDVENLAKFVNFLHNRSELVGRL-------NNWFKFY 1582
            .|..|:  |.:..|.  |.|.:.|:::.....|..     |..:.|..|||       .:|
  Fly  1359 KGMTLKLVVNVQPDNMVAMLTKIEDDIYMTYPNAE-----LKEKYEFSGRLTFQISKDTSW---- 1414

  Fly  1583 VPVGHIVYSFLYGAMEKNKLRLNVSDYCIYQADMMSVVAQVQETRAQLK 1631
                    |.::..:|.|:...::.||.:.|..:.....::.|.|.:.|
  Fly  1415 --------SEIFEYVEGNRSSWHLEDYSLSQPSLEDAFEEIAEERRKKK 1455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	25/154 (16%)
		ABC2_membrane_4	<293..448	CDD:289500	28/172 (16%)
		EcfA2	499..717	CDD:224047	57/218 (26%)
		P-loop_NTPase	500..721	CDD:304359	58/221 (26%)
		ABC2_membrane_3	<972..1254	CDD:289468	67/318 (21%)
		EcfA2	1307..1521	CDD:224047	51/213 (24%)
		P-loop_NTPase	1324..1524	CDD:304359	50/199 (25%)
CG42816	NP_730301.3	CcmA	336..643	CDD:224054	76/315 (24%)
		ABC_subfamily_A	339..556	CDD:213230	58/221 (26%)
		ABC2_membrane_3	<821..1018	CDD:289468	50/236 (21%)
		CcmA	1135..1450	CDD:224054	73/332 (22%)
		ABC_subfamily_A	1136..1354	CDD:213230	52/218 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I3722
eggNOG	1	0.900	-	-		E2759_KOG0059
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm51427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	9	8.970