Protein Alignment CG1801 and AgaP_AGAP001523

DIOPT Version :9

• Sequence 1: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_321601.5
• Gene: AgaP_AGAP001523 / 1281655
• VectorBaseID: AGAP001523
• Length: 1616
• Species: Anopheles gambiae
• Alignment Length: 1713
• Identity: 353/1713 - (20%)
• Similarity: 658/1713 - (38%)
• Gaps: 408/1713 - (23%)

  Fly    89 FTPETTFTSEVTKNVAKTLELSS--TVGYESESEMQNQFDERTTLA------GIVFNDL-RDDGT 144
            :||.|..|..:.:.|.:.|.::.  .|..:|::||     |.|.|.      |:.|.:| :..|.
Mosquito    24 YTPRTEQTETLMEAVRQRLFIADERVVPCDSDTEM-----EFTLLGDPYLGFGVSFQNLSQHGGG 83

  Fly   145 PLTLSISIRFPSEFRTIAPFLTEDRLWITRCSGRINPGRD-RAKHDKQQDIYIREGFLQLQH--- 205
            ||...|..: .:.|||...:                 .|| .:.:.|:.:.|:..|||.||:
Mosquito    84 PLQYVIRTK-NNNFRTQMVY-----------------SRDVLSAYQKRDNEYVESGFLALQNAVE 130

  Fly   206 QIFVEWYHQLRKDIVSTYPEP-------NVEVYNILLKAADEPCSVM--SVAQLPTFLYNFIYLL 261
            |.:|:..::.:.........|       :|.|.:  .:...||..::  ::|.:.|.:.:..|:|
Mosquito   131 QSYVDMAYRQKHASQQDEHAPRLALAFGHVPVDD--SRGPQEPTKILDATIAMMVTMVASSTYIL 193

  Fly   262 PFLNIIRNVAAQVEDGVMVHQWHYGYSFGMQWGIKFLVLFLRMCILGVIYTIMLLAF----WGFG 322
             .|.|:.:.|..:.:.:.:....   |:..:..: ||:.|:::.  .|:|....:||    |...
Mosquito   194 -LLVIVEDRANGMNEFLKIATLQ---SYWKEVAL-FLINFVQLS--AVLYVCYAIAFAHGTWDAN 251

  Fly   323 GRE-------GEFSGTGTIAFVCFI--TLYT-------VEIIITGMVVAKLFAN---------PT 362
            ..:       |.|.....:.|..|:  ||.|       |.:::.|.::...|::         |.
Mosquito   252 AAQVVYLYLLGTFFVANLVTFNFFLSTTLETSAIATAVVPVVVFGPLILAHFSSGLMWLCIIFPA 316

  Fly   363 NAV---------------LFAL---------------MLWLFMYAAFCIILERYWDIHKYYVF-- 395
            |.:               ||.:               :||::   .|.:|....|.:..|||.
Mosquito   317 NGLYYGGTIFHSFKSSGHLFGVGDVATTDYPGVPPVSLLWVY---CFQLIGTLVWSVLWYYVSNV 378

  Fly   396 ------------FILVAFCNCQM---HFSMSLFRNCIEKPEMVNTIDFVLIFTSAISSALIYFLI 445
                        |.|.|.|...:   |.|.|  ||.|....:.|         ||.:|.::.
Mosquito   379 FPGRYGTPKPMGFFLPAQCGWSLKLGHGSSS--RNQITAESLNN---------SAQNSNIVD--- 429

  Fly   446 LLAIQWRMPGTFLSRRIVNNRPRKQQESDTTIMYLGRAPSFQNFEFGDVGSVELMRLRHVSTSHR 510
             |.::.:.|           .|.|...:||..:                  |.:..|..|..|.:
Mosquito   430 -LELEDQGP-----------EPNKAPGADTQQV------------------VRIANLTKVFHSRK 464

  Fly   511 DSERKILKNISMRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPNGEARRLV 575
            ...:.::||..:.||...:.|:|||.|:||.|.:.|:.|:.....|.:.:.|
Mosquito   465 SGAKVVVKNFGLSIYSNSITVLLGHNGAGKTTTMNIITGMVPRTSGTIVVDG------------- 516

  Fly   576 DFRFDEHGLNKHLTVEQTIDYHVRLKLSPSES---------------------DRYEIERRKWLA 619
                 ||..|:         |..::...|...                     .|.|.|:...|.
Mosquito   517 -----EHDANR---------YRHKIGFCPQHDVFFSYLSCLEHLVFFGCLRGLGREEAEKEAKLV 567

  Fly   620 ILDQH-VESRGVRIGKLSSGSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAEKEN 683
            :...| ::.....:..||.|..:.::|...|.|.|.::||:|||:.|.....:..|.|:...::|
Mosquito   568 LEKVHLLDKSDALVHTLSGGMKRRLSLAIALVGATKLLILDEPTSGLDPESRRDIWDILLNLRQN 632

  Fly   684 RAFIIATYNVGEAEHVADRIGILSMGVLEASGTPFFLRSKFSSSVDLVIIKKPHVPDQPITDYIN 748
            ...::.|:.:.||:.:.|.:.|:..|.|.|.|:|.||:.::.....|.::|......:.....|.
Mosquito   633 HTILLTTHFMEEADVLGDWVAIMEEGELVAFGSPLFLKQQYGKGYTLKLLKGATFDKRETWQRIQ 697

  Fly   749 QFMQNIEPENEIGDSLTYRLPVIYRPRLQKLLIHLEIDRKMLGIENVRVVGAELSDIYMTLVTSF 813
            |.:.|....:.:.:.....||.....:...||..||..::.||||.:.:..|.|.::::. .::.
Mosquito   698 QLIPNATVRDTVQEIFAATLPYDEIRKYAPLLKELEATQQELGIETIDIANATLEEVFLN-SSNR 761

  Fly   814 RLQQQMIPD------------VTQTFKYQV-VSQKQLT----KQRMRAMFYKKMIHTAPN----- 856
            |.:.|..|:            .....:.:| :...:||    :....|::.||.||...|
Mosquito   762 RKELQHHPESVDFVDSPTSPAAENLIEIEVALHPSKLTFPEARNTFMAIWRKKWIHIKCNTHVYG 826

  Fly   857 ---VWPIIMIFTSFVLIAIIARLSVLLDMPKERQNSIHIGF---------REPE---------DV 900
               |.|.::....|.|.:.|...:..|.......:||:..|         |:.|         |:
Mosquito   827 WLAVLPPLVTVLCFTLTSGITDAAKALPAVTLTADSIYQAFGVLVVNRGDRDDEFWDREAIQSDL 891

  Fly   901 VKYLPNLKDCGYIDIRSAVKVNKKKSVGVSRTFDDDSFVCEKGSYRNNLRKKNELRSFGAVESDG 965
            .::..|       .:|..:..|...:..:....|.|     ..:||:.|....|..    |.:||
Mosquito   892 DRHPVN-------GVRMMLLENYALADALQELIDKD-----YTTYRDRLVVGIECN----VTADG 940

  Fly   966 DEHLNGYISQDMFHSAPMMLNLLQNVILRLSYPMQTDLVVLVENHPLPTQLSQKINVLDNKIAHI 1030
             .|:....:.::.|||.:..::...|:||. |..:.|..|...|.|     |.:..::|.|..:.
Mosquito   941 -VHVAVLYNNNLLHSAGIAESVTTTVLLRY-YAGEADATVHTRNIP-----STRKQLIDIKTPYY 998

  Fly  1031 HVPLVVGCIIPLTVSVFVIPLVEEEIYDVRFLQHMAGLGLKVFWGINLFWDWFTFFVYSVIIVVI 1095
            ...|:........:....:|| :|.:...|.||:   :...::|.....:| .|..:...::|:.
Mosquito   999 FTELIAIAFYFYVLMYLQVPL-QEHLSGFRQLQN---INRYLYWASTYAFD-LTIHLAECLVVLA 1058

  Fly  1096 MSLMGIGGFGFYENAIMVVL--LTTFGLAALPLTYLVSMFVNKSIVRAFLVS-VLLQGVSGLVLY 1157
            :.|:......|.|::...:.  |..:|:.|||:.|::|..|:.:.....::| :::.||.|:.|.
Mosquito  1059 LVLLLDRTDAFTESSEREIFWTLVVYGVIALPVIYIISQCVDNANTAITIMSYLMIVGVGGVFLL 1123

  Fly  1158 IIYWDVANSNTIFFYAACMSPGFSLLDGVSNVYAQNLEQAICIDKCEATDSCTEENMNEVVPNCK 1222
            ...:|...:|:.:.....:.|.|.|...:..||..  ::.|..::..|..:....:.:
Mosquito  1124 SNGYDDIKNNSGWITVLHVVPEFGLKHSLRVVYEN--QKLILYERLSAEQNRAHSDGH------- 1179

  Fly  1223 FDTFFKWAAPGILPPILYMVLSALIFLMLIFWIE----LHRREK----KFHTSRDLRKM------ 1273
                 .:|.|.|.|.:.|::...|:.|.::...:    ::.|||    ....|:.:||:
Mosquito  1180 -----AFANPRIRPTLFYIISPVLLTLQMLILNQVVENIYTREKVKTSSEAASQSVRKVYRQVSR 1239

  Fly  1274 --------------RTATYPFDDGDVADVKQKIAEADNTKAKQSVF--LVDQVEARVPAAGKR-- 1320
                          |::|..||..|:|.|     .||:...:..:.  |||. ...|..|||:
Mosquito  1240 TMSRAKDRSPSSGKRSSTDGFDQTDLATV-----NADDVTQETELVRSLVDG-GGSVTDAGKKYA 1298

  Fly  1321 ---------------IHTVSFALNKYMSMGIFGPRNSGKSHLMRQLVGQRGFAFGEIYVRGLDFK 1370
                           :.:||||:.:....|:.|...:||:.:.:.|........|:||::..:.:
Mosquito  1299 IVVQELQKTYTNHEAVKSVSFAVKQGECFGLLGMNGAGKTTVFQMLSRNLPLTGGKIYLQQCEVQ 1363

  Fly  1371 -YDLESIHTYMGYSPQHRGLLNELTPREHIRLLCMIRGVPEAKIGEKMHDLCLMLNMTGWM---- 1430
             .|........||.||...||:.:|..|.|.....|:|: ||:  :|        ::..|:
Mosquito  1364 AADALQYRRQYGYCPQFDVLLDFMTVYEVIDYFAQIKGI-EAR--DK--------HIMSWLVKLD 1417

  Fly  1431 ------H--RKCSLLTAEKRHKLKIALALVAYNKILVLDEPTCGMPATTRREIWNILRYIRYCGK 1487
                  |  |.||   ...:.|:...|||:....:::|||||.|:...:||.:|..::.|:...:
Mosquito  1418 IVEYRDHALRDCS---GGTKRKVNTILALLGGPSVVLLDEPTTGVDPKSRRFLWKTIKTIQRKHQ 1479

  Fly  1488 TIIFATNDELECKILADFIILFQDSEMLAIGSLQYLRYKYSHGFYLEVRL---IRDGATLAESE- 1548
            ||:..::...||:.|.:.:.:.....:..:|::..|:.::.||:.|.::|   :.||....|.|
Mosquito  1480 TILLTSHSMDECEELCNRLSIMVGGRLRCVGTIPELKKRHGHGYNLWIKLNVSLADGGNNTEQEI 1544

  Fly  1549 ---------ENLRKDVENLAKFV 1562
                     .:|::..:.|.||:
Mosquito  1545 RQTVTERFNASLQEGHQGLLKFI 1567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	32/191 (17%)
		ABC2_membrane_4	<293..448	CDD:289500	44/230 (19%)
		EcfA2	499..717	CDD:224047	54/239 (23%)
		P-loop_NTPase	500..721	CDD:304359	56/242 (23%)
		ABC2_membrane_3	<972..1254	CDD:289468	57/284 (20%)
		EcfA2	1307..1521	CDD:224047	58/243 (24%)
		P-loop_NTPase	1324..1524	CDD:304359	52/212 (25%)
AgaP_AGAP001523	XP_321601.5	ABC2_membrane_3	<87..374	CDD:289468	55/316 (17%)
		CcmA	450..761	CDD:224054	75/356 (21%)
		ABC_subfamily_A	451..670	CDD:213230	57/245 (23%)
		ABC2_membrane_3	909..1144	CDD:289468	53/255 (21%)
		CcmA	1298..1608	CDD:224054	65/284 (23%)
		ABC_subfamily_A	1299..1516	CDD:213230	52/230 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X215
TreeFam	0	0.000	Not matched by this tool.
	6	5.920