DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1801 and AgaP_AGAP012005

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	XP_320530.4	Gene:	AgaP_AGAP012005 / 1280669	VectorBaseID:	AGAP012005	Length:	735	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	49/239 - (20%)
Similarity:	94/239 - (39%)	Gaps:	46/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   456 TFLSRRIVNNRPRKQQESDTTIMYLGRAPSFQNFEFGDVGSVELMRLRHVSTSHRDSERKILKNI 520
            |..:.::::.:..|.:...|......|..:| :..|||                    :.:|:|.
Mosquito   181 TATASQVISKKDNKMESKGTNRSMDIRIDNF-DVSFGD--------------------KTLLQNA 224

  Fly   521 SMRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPNGEARRLVDFRFD----- 580
            .:.:..|..:..:|..|.||.|||::::|.:..:..::.::....|..|:....:|...:
Mosquito   225 DLLLASGRRYGFVGRNGLGKTTLLKMISGKQLQIPSHISVLHVEQEVVGDDTTALDSVLEVDTVR 289

  Fly   581 ------EHGLNKHLTVEQTIDYHVRLKLSPSESDRYEIERRKWLA----ILD-----QHVESRGV 630
                  |..||..:....| |.::..:||...:....||..|..|    ||:     :.:::|..
Mosquito   290 TELLQRERDLNAQIAAGST-DANLGNELSEVYNQLQTIEADKAPARASIILNGLGFTKEMQARAT 353

  Fly   631 RIGKLSSGSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFW 674
            |  ..|.|....:||...|.....:::|:|||..|..:  .|.|
Mosquito   354 R--TFSGGWRMRLALARALFSKPELLLLDEPTNMLDIK--AIIW 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047	41/196 (21%)
		P-loop_NTPase	500..721	CDD:304359	41/195 (21%)
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047
		P-loop_NTPase	1324..1524	CDD:304359
AgaP_AGAP012005	XP_320530.4	PLN03073	8..727	CDD:215558	49/239 (21%)
		ABCF_EF-3	206..427	CDD:213188	46/214 (21%)
		ABC_tran_Xtn	425..508	CDD:289608
		ABCF_EF-3	520..711	CDD:213188
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910