Protein Alignment CG1801 and AgaP_AGAP010582

DIOPT Version :9

• Sequence 1: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_314549.4
• Gene: AgaP_AGAP010582 / 1275311
• VectorBaseID: AGAP010582
• Length: 1610
• Species: Anopheles gambiae
• Alignment Length: 1698
• Identity: 345/1698 - (20%)
• Similarity: 634/1698 - (37%)
• Gaps: 413/1698 - (24%)

  Fly    72 LTRMADSKREKTKYILAFTPETTFTSEVTKNVAKTL--ELSSTVGYESE-----SEMQNQF---- 125
            |.|..|..||..:.::...........|..||...|  ::.|.:.|::|     :.:.|.|
Mosquito    24 LLRTDDEVRESFQSLINLAKSPLIKMFVGGNVNIELIEDMLSGILYDNEVAKAVNTIANIFDCFS 88

  Fly   126 --------DERTT-------------LAGIVFND------------LRDDGTPLTLSISIRFPSE 157
                    ||:|.             .||:.|.:            :|.|.||:|:.
Mosquito    89 ADRFIPVSDEQTLEDRAFELNRKKLFFAGVYFENGTTANEITYKIRMRTDDTPVTVE-------- 145

  Fly   158 FRTIAPFLTEDRLWITRCSGRINPGRDRAKHDKQQDIYIREGFLQLQHQIFVEWYHQLRKDIVST 222
                    ..:|.|.        ||.:.:   .:.|:....||:|:||.:.:....|.:|::.:.
Mosquito   146 --------NRNRFWF--------PGPEAS---FELDMRYHRGFIQIQHAVDMGIIRQAKKEMFNK 191

  Fly   223 YPEPNVEVYNIL---------LKAADEPCSVMSVAQLPTFLYNFIY--LLPFLNIIRNV------ 270
            ..:...|..:..         .|..:...:..||::..|...:.:|  |...||:.::|
Mosquito   192 QSKEKSEDSSPFGGELELTDDFKVEETTATPASVSETTTENLSSLYGDLSKRLNVSQDVLDRFGG 256

  Fly   271 ---AAQVEDGV-MVHQWHYGYS------------FGMQWGIKFLVLFLRMCILGVIYTIMLLAFW 319
               ::.:||.: .......|.|            ...|....||.||
Mosquito   257 GSNSSALEDFLDFKDDDEEGSSSETSATTTAMPVLSRQKRQSFLDLF------------------ 303

  Fly   320 GFGGREGEFSGTGTIAF-VCFITLYTVEIIITGMVVAKLFANPT------NAVLFALM------- 370
             |||  |....|..:.: |.....||           |.|..|.      |::|...|
Mosquito   304 -FGG--GSKKSTNELEYKVANEKFYT-----------KQFPYPKYTKDDGNSMLMRSMGLKSGSE 354

  Fly   371 --LWLFMYAAFCIILERYWDIHKYYVFFILVAFCNCQMH------------FSMSLFRNCIEKPE 421
              .|.....:|.                  .|||....|            || |.||..|.:.:
Mosquito   355 TVSWFVANLSFS------------------TAFCYAWRHVIRMELQHRGANFS-SAFRGAIAEND 400

  Fly   422 MVNTIDFVLIFTSAISSALIYFLILLAIQWRMPGTFLSRRIVNNRPRKQQESDTTIMYLGRAPSF 486
            :...|..:|:      .|:|||                                ||.||.:....
Mosquito   401 LKFGILMILL------DAVIYF--------------------------------TIGYLYQCFKK 427

  Fly   487 QNFEFGDVGSVEL-----MRLRHVSTSHRDSERKILKNISMRIYRGEVFVILGHIGSGKLTLLRI 546
            ....|..|..::|     ..||:|..::....:|:|.::|:...|.||..:||..|:||.|::::
Mosquito   428 DETTFHTVKRIKLDKSIGAELRNVDVAYEKGGKKVLSDVSITFRRDEVTCLLGRNGAGKSTIIKL 492

  Fly   547 LAGLKFPLRGNVYIMGNPFEPNGEARRLVDFRF--------DEHG-------LNKHLTVEQTIDY 596
            |.|...|:.|:|::.             :|:.|        ::.|       |..:||.::.:..
Mosquito   493 LTGQVRPIEGDVHLP-------------LDYDFISGIRNNAEKIGLCPQNDVLIPNLTAKEHLQL 544

  Fly   597 HVRLKLSPSESDRYEIERRKWLAILD----QHVESRGVRIGKLSSGSMKLVALCCCLAGDTPIII 657
            :.|:||:..    ::.|..:.|..|.    ||     .|...||.|..:.:.:.....|...::|
Mosquito   545 YARIKLTRG----FDTEVSRTLENLKMGPYQH-----YRASDLSGGFKRRLCIAIAFLGSPNLVI 600

  Fly   658 LEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEAEHVADRIGILSMG--VLEASGTPFFL 720
            |:||.:.:..:..:..|.::...:::||.|:||:::.|||.::|:|.:|..|  :||.|...  |
Mosquito   601 LDEPCSSVDTKARKYIWELIQTLRKDRAVILATHHLDEAECLSDKIVMLENGKAILEQSQEE--L 663

  Fly   721 RSKFSSSVDLVIIKKPHVPDQPITDYINQFMQNIEPENEIG-------DSLTYRLPVIYRPR--L 776
            :.:|::::.|.|..| |..|...|..|.|..:.::...::.       :.|.:::.......  :
Mosquito   664 KKRFTNTIYLSIFLK-HQTDVDRTVMIAQLSKLLDGTVDLRYDMSATLNQLDFKITSSTNDSQVI 727

  Fly   777 QKLLIHLEIDRKMLGIENVRVVGAELSDIYMTLVTSFRL-QQQMIPDVTQTFKYQVVS------- 833
            :.||.|:...:....|::..:....|.:|:.|:..|... ...|:.:...|....:.:
Mosquito   728 EPLLEHMAQLKSQKQIDSFEIRNENLLNIFSTVNASDPTPADPMLQNGNGTSATHIPNGFHGPKT 792

  Fly   834 --QKQLTKQRMRAMFYKKMIHTAPNVWPIIMIFTSFVLIAIIARLSVLLDMPKERQNSIHIGFRE 896
              .|..|...|..:|.|:|.|...|...::.:.....:..|||...:.:..|.|....::.....
Mosquito   793 NDSKLSTMSIMWTLFCKRMRHFMRNYRLLVCLLVLPTIFEIIAMGFMTIRPPGEHDLMVNFSTAL 857

  Fly   897 PEDVVKYLPNLKDCGYIDIRSAVKVNKKKSVGVSRTFDD--DSFVCEKGSYRNNLRKKNEL--RS 957
            .....::..|..|..  :.|.|:     .|..::...|:  ..|.....:||..|...::.  |.
Mosquito   858 YPRSAEFYTNATDGD--EYRDAI-----VSDVLAHCTDEYCSIFNSSYEAYRWVLSTTDDYTERR 915

  Fly   958 FGAVESDGDEHLNGYISQDMFHSAPMMLNLLQNVILRL-----SYPMQTDLVVLVENHPLPTQLS 1017
            :|.:..:.::::..|.::. :||.|..||:|...:||.     ||.::|      .||||..:..
Mosquito   916 YGGITINKEKNIVWYNNKG-YHSMPTWLNMLDTAVLRAELNDSSYTIRT------INHPLKIEED 973

  Fly  1018 Q-KINVLDNKIAHIHVPLVVGCIIPLTVSVFVIPLVEEEIYDVRFLQHMAGLGLKVFWGINLFWD 1081
            : .::.:..:||...:.|::.....|.|:...:.:|.|.|...:..|.:||:.:..:|.:...||
Mosquito   974 ELSVSSMLQQIADAGISLIILLAFSLVVAGASVYIVNERIRGEKLQQRLAGVNVFTYWSVTYIWD 1038

  Fly  1082 WFTFFVYSVIIVVIMSLMGIGGFGFYENAIMVVLLTTF-GLAALPLTYLV------SMFVNKSIV 1139
            ...|.:...:.|::..:..|..:...|....:.||..| |.|.:|..:|.      :.|.|.||
Mosquito  1039 AMIFLIALALAVIVFKVFAIPAYVAREQLEGICLLLVFYGFATIPAVHLFEKLFTDASFANMSI- 1102

  Fly  1140 RAFLVSVL--LQGVSGLVLYIIYWDVANSNTI---FFYAACMSPGFSLLDGVSNVYAQNLEQAIC 1199
              |.::|:  |..::.::|:.|..|...|..|   ...|..:.|..:|.||:..: ::|...|
Mosquito  1103 --FCLNVITALGTLTIIILFDILGDTDESERIRNALNRAFLVLPQHALSDGLIEL-SKNYITA-- 1162

  Fly  1200 IDKCEATDSCTEENMNEVVPNCKFDTFFKWAAPGIL-PPILYMVLSALIFLMLIFWIE------L 1257
                            |:......|::.......:| |.::.:.:...||::|...||      :
Mosquito  1163 ----------------EIFKRYYIDSYKSPVYSTLLHPHLIALAVMGFIFMLLNIAIEYKVVQRI 1211

  Fly  1258 HRR-----EKKFHTSRDLRKMRTATYPFDDGDVADVKQKIAEADNTKAKQSVFLVDQVEARVPAA 1317
            :.|     :.|.|   |:..|.|..|......| :.|:|...||      .:..||.:..|....
Mosquito  1212 YNRIVGTSQPKVH---DINGMDTPDYSTVISRV-EGKKKSITAD------QILSVDNLRKRYRGC 1266

  Fly  1318 G---------KRIHTVSFALNKYMSMGIFGPRNSGKSHLMRQLVGQRGFAF--GEIYVRGLDFKY 1371
            |         :.:..|||.|......|:.|...:|||.:         ||.  ||:...|..|.:
Mosquito  1267 GGGGGGAKGLEVVKDVSFKLRYGECFGLLGTNGAGKSTI---------FAILSGELLPSGGSFTF 1322

  Fly  1372 DLESIHTYMGYSPQHRGLLNELTPREHIRLLCMIRGVPEAKIGEKMHDLCLMLNMTGW---MHRK 1433
              .|.|. ..|.||:..|...||..|.|.....:|.:...       |..:|..:..:   .:||
Mosquito  1323 --YSTHG-PSYCPQNNFLDPLLTVEEVIVFYGKLRNIESI-------DKLIMETLKEYHLEAYRK 1377

  Fly  1434 CSL--LTAEKRHKLKIALALVAYNKILVLDEPTCGMPATTRREIWNILRYIRYCGKTIIFATNDE 1496
            ..:  |:...|.||.:|::....::|:::||||..:...||..:::.:..:....::|:..::..
Mosquito  1378 VLVKNLSGGNRRKLCVAVSCFGQSEIILMDEPTSDLDPVTRSIVYSTIERLNAQNRSILLTSHSI 1442

  Fly  1497 LECKILADFIILFQDSEMLAIGSLQYLRYKYSHGF----YLEVRLIRDGATLAESEENLRKDV-- 1555
            .|...:...|.:.:|.|:|.:.:...|:.::.|.:    |||.....|...:.:.|.|:.:|:
Mosquito  1443 SEIDRICQRIAILKDGELLTVDTPDRLKERFGHSYQITLYLEGLREVDFLRVIKREFNVTRDIIL 1507

  Fly  1556 -ENLAKFV 1562
             :|..:||
Mosquito  1508 HKNSVQFV 1515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	32/172 (19%)
		ABC2_membrane_4	<293..448	CDD:289500	36/182 (20%)
		EcfA2	499..717	CDD:224047	60/243 (25%)
		P-loop_NTPase	500..721	CDD:304359	59/241 (24%)
		ABC2_membrane_3	<972..1254	CDD:289468	67/300 (22%)
		EcfA2	1307..1521	CDD:224047	52/229 (23%)
		P-loop_NTPase	1324..1524	CDD:304359	48/206 (23%)
AgaP_AGAP010582	XP_314549.4	CcmA	447..728	CDD:224054	70/305 (23%)
		ABC_subfamily_A	447..664	CDD:213230	59/240 (25%)
		ABC2_membrane_3	819..1201	CDD:289468	84/417 (20%)
		NatA	1253..1498	CDD:226927	58/263 (22%)
		ABC_subfamily_A	1254..1470	CDD:213230	52/234 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920