DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1801 and AgaP_AGAP002638

DIOPT Version :9

Sequence 1:	NP_728408.3	Gene:	CG1801 / 33104	FlyBaseID:	FBgn0031171	Length:	1655	Species:	Drosophila melanogaster
Sequence 2:	XP_312290.4	Gene:	AgaP_AGAP002638 / 1273324	VectorBaseID:	AGAP002638	Length:	776	Species:	Anopheles gambiae

Alignment Length:	316	Identity:	82/316 - (25%)
Similarity:	126/316 - (39%)	Gaps:	56/316 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1255 IELHRREKKFHTSRDLRKMRTATYPFDDGDVADVKQKIAEADNTKAKQSVFLVDQVEARVPAAGK 1319
            ::|..|.|||.:......:|.        ..|...::..:...||...:|.| |.:...||
Mosquito    25 LDLAARRKKFMSQPSTVAIRR--------QQAVCVRRAHKIYGTKKNPNVIL-DGLNMTVP---- 76

  Fly  1320 RIHTVSFALNKYMSMGIFGPRNSGKSHLMRQLVGQRGFAFGEIYV-------RGLDFKYDLESIH 1377
                      |....|:.|....||:.|:..:||:|....|||:|       ||....      .
Mosquito    77 ----------KGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVP------G 125

  Fly  1378 TYMGYSPQHRGLLNELTPREHIRLLCMIRGVPEAKIGEKMHDLCLMLNMTGWMHRKCSLLTAEKR 1442
            ..:||.||...|..|.|.||.:.....|.|:...::.||...||.:|.:.. ..|....|:..::
Mosquito   126 PRVGYMPQEVALYGEFTIRETLIYFGWIYGMTTDQVDEKTDFLCKLLQLPN-ASRFVKNLSGGQQ 189

  Fly  1443 HKLKIALALVAYNKILVLDEPTCGMPATTRREIWNILRYIRYCGKTIIFATNDELECKILADFII 1507
            .::.:|.||:...::|:|||||.|:....|:.||:.|..|...|.|.:..|...:|....|..|.
Mosquito   190 RRMSLAAALLNEPELLILDEPTVGVDPVLRQSIWDHLVEITKSGNTTVIVTTHYIEETRQAHVIG 254

  Fly  1508 LFQDSEMLAIGSLQYLRYKYSHGFYLEVRLIRDGATLAESEEN--LRKDV-ENLAK 1560
            |.:..:.||..|...|..:|.                |||.|:  |:..| :|:.|
Mosquito   255 LMRGGKFLAEESPADLLAQYQ----------------AESLEDVFLKLSVLQNMGK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468
		ABC2_membrane_4	<293..448	CDD:289500
		EcfA2	499..717	CDD:224047
		P-loop_NTPase	500..721	CDD:304359
		ABC2_membrane_3	<972..1254	CDD:289468
		EcfA2	1307..1521	CDD:224047	61/220 (28%)
		P-loop_NTPase	1324..1524	CDD:304359	58/206 (28%)
AgaP_AGAP002638	XP_312290.4	PQQ_ABC_ATP	48..286	CDD:274822	73/275 (27%)
		ABC_DR_subfamily_A	56..261	CDD:213197	62/226 (27%)
		ABC2_membrane_3	394..769	CDD:289468
		ABC2_membrane	569..737	CDD:279410
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900