Protein Alignment CG1801 and abca10

DIOPT Version :9

• Sequence 1: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_031750511.1
• Gene: abca10 / 100485734
• XenbaseID: XB-GENE-6464279
• Length: 1610
• Species: Xenopus tropicalis
• Alignment Length: 1850
• Identity: 389/1850 - (21%)
• Similarity: 701/1850 - (37%)
• Gaps: 509/1850 - (27%)

  Fly     5 KGLLFKRYIRIELNLWRRTLFEIVALVIMVLVIFLNPIAHSKRLLYTTTENENEQSIVSHKLQDI 69
            |.||.|         |||.....:..:..:..:||..:..:..|...|::.:...:.|..:|...
 Frog    21 KNLLLK---------WRRKWHSTLEWLQNLAFVFLMFLTVAIELYGPTSDIDLSPAWVLGRLDAF 76

  Fly    70 NILTRMADSKREKTKYILAFTPETTFTSEVTKNVAKTLELSSTVGYESESEMQNQFDE------- 127
            |.|:             :.:...|:.:.::.:.|||.:.:       .:.::|...||
 Frog    77 NNLS-------------VGYVHTTSTSRDIMEKVAKGIIV-------PDIKVQEFADEEELIEAV 121

  Fly   128 -RTTLAGIVFNDLRDDGTPLTLSISIRF-------PSEFRTIAPFLTEDRLWITRCSGRINPGRD 184
             ..::..:.|.|        ..|..||:       |:::........:|   ::.|    ||
 Frog   122 SNMSMVAVTFVD--------EFSYHIRYQLPKRKHPNDYFAYMGNCGDD---LSYC----NP--- 168

  Fly   185 RAKHDKQQDIYIREGFLQLQHQIFVEWYHQLRKDIVSTYPEPN--VEVYNILLKAADEPCSVMSV 247
                    ..|..||||.||..|     .....|:.|.:...|  ..:..|.:|:|:....|:
 Frog   169 --------TYYWSEGFLSLQASI-----DSAIIDLTSNHSVWNNMASIVAIKMKSAERSYKVL-- 218

  Fly   248 AQLPTFLY-------NFIYLL------------PFLNIIRNVAAQVEDGVMVHQWHYGYSFGMQW 293
            |.:.:|::       :.:|||            ..|.::|     ::|          .:|.:.|
 Frog   219 AHVASFIFVMPMCYVSLMYLLSQYVTRERYEMKETLRLMR-----LQD----------LAFWLSW 268

  Fly   294 GIKFLVLFLRMCILGVIYTIMLLAFWGFGGREGEF--SGTGTIAFVCFITLYTVEIIITGMVVAK 356
            |:      |..|.:.::..:|.|....|     .|  |..|.|.|:.|  ||.|.::....:::.
 Frog   269 GL------LYSCYVFIVANLMTLVTKPF-----VFITSSYGIIMFMFF--LYGVALMSFTFMLSA 320

  Fly   357 LFANPTNAVLFALMLWLFMYAAFCIILERY--------WDIHKYYVFFI----LVAFCNCQ--MH 407
            ||.||....:....:.|.:.|...|:|.::        ..|...:.|.:    .|...|.|  ::
 Frog   321 LFRNPRATAIAGFFITLLLSALGLILLSKHVPKSVEVLLSIFPQFAFAVGITQSVHMENDQEGVY 385

  Fly   408 FS-----MSLFRNCIEKPEMVNTIDFVL--IFTSAISSALIYFLILLAIQWRM---PGTFLSRRI 462
            ||     .|...:|.        |..||  :|...::   :||..:||.:..:   |..||....
 Frog   386 FSDLTGGSSHMLSCF--------ISLVLDSVFYMGLT---LYFEKVLADKHGVKHEPLFFLKASY 439

  Fly   463 VNNR---PRKQQESDTTIMYLG----RAPSFQNFEFGDVGSVELMRLRHVSTSHRDSER--KILK 518
            .:..   |...|..|:....||    :.|:       |:...|.:|:..|..::.|.::  :.|:
 Frog   440 WSKEKPSPLMAQTDDSGESSLGHFVEKVPA-------DLHGKEAIRIHGVKKTYYDKDKNTEALR 497

  Fly   519 NISMRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPN----GEARRLV---- 575
            ::.:.||.|::..:|||.|:||.|||.||:|: .|..|....:.|....|    ||.::.|
 Frog   498 DLDLNIYEGQITALLGHSGAGKTTLLNILSGM-CPTSGGSATVCNYKLSNMRHLGEIKKRVGFCP 561

  Fly   576 --DFRFDEHGLNKHLTVEQTIDYHVRLKLSPSESDRYEIERRKWLAILD-QHVESRGVRIGKLSS 637
              |.:||.      |||::.:.....:|..||:    |:..:....:.| |..:...:...|||.
 Frog   562 QGDIKFDP------LTVKENLTVFAMIKGIPSK----EVAHKVQTVLSDLQMNDIENIEASKLSG 616

  Fly   638 GSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEAEHVADR 702
            |..:.:.....:.||..:::|:|||..|........|:|:...|.:|..:::|..:.||:.:|||
 Frog   617 GQKRKLTFGIAILGDPQVLLLDEPTAGLDPCSRHNIWTILKESKADRVTLLSTQFMDEADILADR 681

  Fly   703 IGILSMGVLEASGTPFFLRSKF------------SSSVDLVI-IKKPHVPDQPITDYINQFMQNI 754
            ..::|.|.|:..||..||:.|:            |..|:|:. |.|.|:|...:|
 Frog   682 KVVISKGKLKCVGTSLFLKRKWGVGYHLRMQVSPSCDVELMTSIIKQHIPSTKLT---------- 736

  Fly   755 EPENEIGDSLTYRLPVIYRPRLQKLLIHLEIDRKMLG--IENVRVVGAELSDIYMTL-------- 809
             .:||  :.|||.||.........|.:||:   ..:|  |.|..|....|.|:::.|
 Frog   737 -TQNE--EELTYTLPFENMDVFPDLFLHLD---GQVGNSIVNYGVSMTTLDDVFLKLEGEGEIES 795

  Fly   810 ----------------------VTSFRLQQQMIPDVT----QTFKYQV--VSQKQLTKQR----- 841
                                  :....||.....:||    :.::.||  |::.:|.|.|
 Frog   796 GDYDVFNPESRTNEDREDFSTEMEESLLQMSDSGNVTLSGWELWRQQVLAVARIRLLKLRHDTKS 860

  Fly   842 MRAMFYKKMIHTAPNVWPIIMIFTSFVLIAIIARLSVLLDMPKERQNSIHIGFREPED-VVKYLP 905
            .|::....::.|.|   |||:|.||.::....|           .:.:.|:.|:.|.: :.||..
 Frog   861 FRSILLLLVVITLP---PIIIIITSNIVNTFDA-----------WELTPHLYFQSPRNRLNKYYT 911

  Fly   906 NLKDCGYI-----DIRSAVKVNKKKSVGVSRTFDDDSFVCEKGSYRNNLRKKNELRSFGAVESDG 965
            :|..|...     |...|||....:...|:..:|.::.     .||            ||:|...
 Frog   912 DLLICNNTGSSIEDFVGAVKEQNIEVQVVNGEYDTETV-----KYR------------GAIEVSQ 959

  Fly   966 DEHLNGY-----ISQDMFHSAPMMLNLLQNVILRLSYPMQTDLVVLVENHPLPTQLSQKINVLDN 1025
            .|  .||     .:...|:|.|::||::.|.:|::   ::......|.|||:.|..:..|
 Frog   960 ME--KGYNFTIVANPKAFNSLPVLLNIISNALLKI---LKVSGHFRVWNHPITTDGTDII----- 1014

  Fly  1026 KIAHIHVPLVVGCIIPLTVSVFVIPLVEEEIYDVRFLQHMA------------------GLGLKV 1072
                         .:|....:|.|      |:...|..|:|                  ||....
 Frog  1015 -------------FLPYMSLIFFI------IFASAFCPHIAMSSTEDNRINARNQLRISGLFPSA 1060

  Fly  1073 FWG----INLFWDWFTFFVYSVIIVVIMSLMGIGGFGFYENAIMVVLLTTFGLAALPLTYLVSMF 1133
            :|.    :::...|...|:...|.....|.:.:   .|....:|::.:..:|.|.:...|::|..
 Frog  1061 YWFGQALVDVILYWILLFLMVAIYFAFNSYILL---DFVPAMVMIIGIIGYGTAMVLYVYVISFI 1122

  Fly  1134 VNKS------------IVRAFLVSVLLQGVSGLVLYIIYWDVANSNTIFFYAACMSPGFSLLDGV 1186
            ..:.            |...|  .|:...|....|:.||:        |.:.|      |.|.|:
 Frog  1123 FGRGKSHTDSWSLFFVITSTF--PVMFMDVFMFRLFTIYY--------FVFPA------SALSGI 1171

  Fly  1187 S------NVYAQNLEQAICIDKCEATDSCTEENMNEVVPNCKFDTFFKWAAPGILPPILYMVLSA 1245
            .      .|:....|....|::|                                .|.|:::
 Frog  1172 MEYTYRLQVFPGGSEYTALIEQC--------------------------------TPYLHII--- 1201

  Fly  1246 LIFLMLIFWIELH------RREKKFHTSRDLRKMRTATYPFD-----DGDVADVKQKIAEA---D 1296
             ||.:|::::|..      ..:..|..||  ||:.|...|.:     |.||...|:::.:|   .
 Frog  1202 -IFFVLLWFLEWKFGLRSLTIDPLFRISR--RKITTKKNPEELGNDVDEDVLAEKERVKKAATIA 1263

  Fly  1297 NTKAKQSVFLVDQV--EARVPAAG------KRIHT--VSFALNKYMSMGIFGPRNSGKSHLMRQL 1351
            |.:.| .|.:.|.:  |.:|...|      ||..|  |||.:.|...:|:.||..:||:..|..|
 Frog  1264 NVEEK-PVIIADSLRKEYKVKKGGSFFKKNKRAATKNVSFCVKKGEVLGLLGPNGAGKTTSMYML 1327

  Fly  1352 VGQRGFAFGEIYVRGLDFKYDLESIHTYMGYSPQHRGLLNELTPREHIRLLCMIRGVPEAKIGEK 1416
            .|:.....||:.:.|    .|......::||.||...|...||.:||:.:...::|:.:......
 Frog  1328 AGEVKPTAGEVLLCG----NDPVGSTGFLGYCPQDNPLWPNLTVKEHLEIYAAVKGMKKEDASIA 1388

  Fly  1417 MHDLCLMLNMTGWMHRKCSLLTAEKRHKLKIALALVAYNKILVLDEPTCGMPATTRREIWNILR- 1480
            ::.:...|.:...|.:....|:.....|:..|::::....|::||||:.|:....::.:|..:|
 Frog  1389 INRVASALELKEHMGKAARKLSLGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQQRLWRAIRA 1453

  Fly  1481 YIRYCGKTIIFATNDELECKILADFIILFQDSEMLAIGSLQYLRYKYSHGFYLEVRLIRDGATLA 1545
            ..:...:..|..|:...|.:.:.|.:.:....::..|||:|.|:.|:..|:.||::       :.
 Frog  1454 AFKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLEIK-------VK 1511

  Fly  1546 ESEENLRKDVENLAKFVNFLHNRSELV---------GRLNNWFKFYVPVGHI---VYSFLYGAME 1598
            ||.:            |:.:||  |::         .|.::...:.:|:.::   ..:||  .:|
 Frog  1512 ESHQ------------VDQIHN--EIIRIFPHAARQDRFSSLLVYKIPMDNVQSLSQAFL--LLE 1560

  Fly  1599 KNKLRLNVSDYCIYQADMMSV---VAQVQE 1625
            :.|...|:.:|...|:.:..|   :|:.||
 Frog  1561 EAKRAYNIEEYSFSQSTLEQVFIELAKEQE 1590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	31/153 (20%)
		ABC2_membrane_4	<293..448	CDD:289500	39/177 (22%)
		EcfA2	499..717	CDD:224047	63/230 (27%)
		P-loop_NTPase	500..721	CDD:304359	65/233 (28%)
		ABC2_membrane_3	<972..1254	CDD:289468	55/326 (17%)
		EcfA2	1307..1521	CDD:224047	53/224 (24%)
		P-loop_NTPase	1324..1524	CDD:304359	47/200 (24%)
abca10	XP_031750511.1	rim_protein	<107..1597	CDD:130324	369/1734 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010