Protein Alignment Abca3 and alsA

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_418511.1
• Gene: alsA / 948593
• ECOCYCID: EG11959
• Length: 510
• Species: Escherichia coli
• Alignment Length: 524
• Identity: 108/524 - (20%)
• Similarity: 191/524 - (36%)
• Gaps: 157/524 - (29%)

  Fly   538 LQMRHLKKRFGNKMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIINGSDIR 602
            :.|..:.|.||....:|.:::.::..||..|||.|||||:|.:.:|:|:..||.||..||
E. coli     6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITIN----- 65

  Fly   603 TNIE--------GARMSLGICPQHNVLFDEMSVSNHI---RFFSR---------MKGLRGKAVEQ 647
             ||.        .|::.:||..|...:.||::|..::   |..::         .:.:|.:|...
E. coli    66 -NISYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLYIGRHLTKKICGVNIIDWREMRVRAAMM 129

  Fly   648 EVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQ 712
            .:...|| ::|::|.    :.||...|:.|.:...|..|.||::.|||:|.:.......|:.::.
E. coli   130 LLRVGLK-VDLDEKV----ANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMN 189

  Fly   713 Q-EKVGRTLLLTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDC---- 772
            | .|.|..::..:|.:.|...:.||..:|.||...|.|.             :..|..||.
E. coli   190 QLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGI-------------VSDVSNDDIVRLM 241

  Fly   773 -------------------------ETNEVTALLNKYIPGLKPECDIGAELSYQ-LPDSASAKFE 811
                                     |...||:...|.:..:......|..|.:. |..|...:..
E. coli   242 VGRELQNRFNAMKENVSNLAHETVFEVRNVTSRDRKKVRDISFSVCRGEILGFAGLVGSGRTELM 306

  Fly   812 E-MFGQLEEQSDELHLNGYGVGITSMEEVFMK-----VGAEKDN--------TGNIKDQHEIMNG 862
            . :||..:....|:.|||..:...|..:...|     ..:.:||        ..|:.....:.:|
E. coli   307 NCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDG 371

  Fly   863 GSGFRGEDDNESVQSDGIF--------SENRRLLQGLQLLS-----------NQWKAMLLKKFLY 908
              |::|        :.|:|        :||:|.|..|:..|           ||.|.::.|
E. coli   372 --GYKG--------AMGLFHEVDEQRTAENQRELLALKCHSVNQNITELSGGNQQKVLISK---- 422

  Fly   909 TW----------------------------------RNKLLLLIQNIMPVFFVVVTILIIKTQGT 939
             |                                  ..|::|::.:.:|....|...:.:..:|.
E. coli   423 -WLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGR 486

  Fly   940 FQEL 943
            ..::
E. coli   487 LTQI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	108/524 (21%)
alsA	NP_418511.1	PRK09700	1..510	CDD:182036	108/524 (21%)