Protein Alignment Abca3 and rbbA

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: YP_026225.1
• Gene: rbbA / 947998
• ECOCYCID: EG12223
• Length: 911
• Species: Escherichia coli
• Alignment Length: 810
• Identity: 170/810 - (20%)
• Similarity: 287/810 - (35%)
• Gaps: 277/810 - (34%)

  Fly   530 EPEGKHIGLQMRHLKKRFGNKMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTA 594
            :||...|.::.|.|..|||:.:.|..::..:...||...||.||.||:||:.||||:.|.:.|.|
E. coli   269 QPENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEA 333

  Fly   595 IINGSDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIELE 659
            .:.|..:.......|..:|...|...|::|::|..::...:|:..:....:...||:..:..:|.
E. coli   334 WLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMSERFKLN 398

  Fly   660 DKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLW----DLLQQEKVGRTL 720
            |..::....|..|::::||:..|:....::::.|||:||:||.||...|    ||.:|:||  |:
E. coli   399 DVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKV--TI 461

  Fly   721 LLTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCETNEVTALLNKYI 785
            .::||||:||:.. |||::|..|::...||
E. coli   462 FISTHFMNEAERC-DRISLMHAGKVLASGT----------------------------------- 490

  Fly   786 PGLKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAEKDNT 850
                |:                        :|.|:.          |..|:||.|:....|....
E. coli   491 ----PQ------------------------ELVEKR----------GAASLEEAFIAYLQEAAGQ 517

  Fly   851 GNIKDQHEIMNGGSGFRGEDDNESVQSDGIFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLL 915
            .|..:...:::         |.......| ||                   |.:.|.|:.|..|.
E. coli   518 SNEAEAPPVVH---------DTTHAPRQG-FS-------------------LRRLFSYSRREALE 553

  Fly   916 LLIQNIMPVFFVVVTILIIKTQGTFQELKPITISLTQYPLAVTVLDRSNV---------QNGTGY 971
            |....:.....::.|::::...|       ..||:....|...||||...         .:|:.|
E. coli   554 LRRDPVRSTLALMGTVILMLIMG-------YGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRY 611

  Fly   972 EI----ANKYEDLARSYGS-----------NYGLELT-GTQGFEDYILDLGKTIQVRINSRYLVA 1020
            .|    ...|::|.|...:           |:|.::. ||.      ::||..|...:.||....
E. coli   612 FIEQPPLTSYDELDRRMRAGDITVAIEIPPNFGRDIARGTP------VELGVWIDGAMPSRAETV 670

  Fly  1021 ATITESKITAWLNNQALHTA--------------------------------PLTVNMVH----- 1048
            ....::...:||.:.|...:                                ||.:.|:.
E. coli   671 KGYVQAMHQSWLQDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSA 735

  Fly  1049 -NAIADKLFGSSVKIQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKE 1112
             :.:.:|..||.:.:.||    |.|.|..|        ||.||.             ||..
E. coli   736 LSVVREKELGSIINLYVT----PTTRSEFL--------LGKQLP-------------YIAL---- 771

  Fly  1113 RESRAKLLQF--VGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGL--STFGELGRYYL 1173
                 .:|.|  :.|:.|:.|.:..    ..|::...|..::.|:.....||  |||.:    ..
E. coli   772 -----GMLNFFLLCGLSVFVFGVPH----KGSFLTLTLAALLYIIIATGMGLLISTFMK----SQ 823

  Fly  1174 LLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFDTKDTADILG-- 1236
            :..:||.|::..|         |||.|:         ||               ....|.:.|
E. coli   824 IAAIFGTAIITLI---------PATQFS---------GM---------------IDPVASLEGPG 855

  Fly  1237 -WIFRIFP--H--------FSLAMSLNKVY 1255
             ||..::|  |        ||.|:.|..::
E. coli   856 RWIGEVYPTSHFLTIARGTFSKALDLTDLW 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	170/810 (21%)
rbbA	YP_026225.1	ABC2_perm_RbbA	12..910	CDD:468210	170/810 (21%)