Protein Alignment Abca3 and ybhF

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_415315.4
• Gene: ybhF / 945413
• ECOCYCID: G6411
• Length: 578
• Species: Escherichia coli
• Alignment Length: 1117
• Identity: 204/1117 - (18%)
• Similarity: 321/1117 - (28%)
• Gaps: 552/1117 - (49%)

  Fly   538 LQMRHLKKRFG--NKMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIINGSD 600
            :.:..|:|||.  :|..|..|...:....:|.|:|.:||||||.:.||.|:..|.||:|.:.|.|
E. coli     6 ITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGAGKTTLMRMLAGLLKPDSGSATVIGFD 70

  Fly   601 IRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIELEDKANVA 665
            ...|.......||..||...|:::::|..::..::.::.:.|:|.:|..|:.|:...|.......
E. coli    71 PIKNDGALHAVLGYMPQKFGLYEDLTVMENLNLYADLRSVTGEARKQTFARLLEFTSLGPFTGRL 135

  Fly   666 SSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQ-EKVGRTLLLTTHFMDE 729
            :.|||||||:||.:.|.|.|:.||:|.|||..|:||.:||:||.::.: ...|..:|.:|.::||
E. coli   136 AGKLSGGMKQKLGLACTLVGEPKVLLLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDE 200

  Fly   730 ADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCETNEVTALLNKYIPGLKPECDI 794
            |:...| :.:|.:|||..||                       |...:|..:
E. coli   201 AEQCRD-VLLMNEGELLYQG-----------------------EPKALTQTM------------- 228

  Fly   795 GAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAEKDNTGNIKDQHEI 859
                                                                             
E. coli   229 ----------------------------------------------------------------- 228

  Fly   860 MNGGSGFRGEDDNESVQSDGIFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLLLLIQNIMPV 924
              .|..|.....:|.         ||:|||....|......|:..|.:.
E. coli   229 --AGRSFLMTSPHEG---------NRKLLQRALKLPQVSDGMIQGKSVR---------------- 266

  Fly   925 FFVVVTILIIKTQGTFQELKPITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGSNYG 989
                   ||:|.:.|                      ..::::..|....|..|...|
E. coli   267 -------LILKKEAT----------------------PDDIRHADGMPEININETTPR------- 295

  Fly   990 LELTGTQGFEDYILDLGKTIQVRINSRYLVAATITESKITAWLNNQALHTAPLTVNMVHNAIADK 1054
                    |||..:||            |..|..:||.:.|     .|||..
E. coli   296 --------FEDAFIDL------------LGGAGTSESPLGA-----ILHTVE------------- 322

  Fly  1055 LFGSSVKIQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKL 1119
                                            ||
E. coli   323 --------------------------------GT------------------------------- 324

  Fly  1120 LQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLP 1184
                                                                             
E. coli   325 ----------------------------------------------------------------- 324

  Fly  1185 FIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFDTKDTADILGWIFRIFPHFSLAM 1249
                                                                             
E. coli   325 ----------------------------------------------------------------- 324

  Fly  1250 SLNKVYTNTATRNACAKAGALPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGVVFFLII 1314
                                                        ||   |||
E. coli   325 --------------------------------------------PG---ETV------------- 329

  Fly  1315 IVLEFRLINELMFKIRQLISKPPPPPTEGQLDDDVANERERILQMSSNELATKNLVLDRVTKYYG 1379
                                                        :.:.||          ||.:|
E. coli   330 --------------------------------------------IEAKEL----------TKKFG 340

  Fly  1380 QFMAVNQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAAYVQGLSLESNMNSIYKMIG 1444
            .|.|.:.|:..|:..|.|||||.|||||:||||||.|....:||.|.|.|:.|:.:.....:.:|
E. coli   341 DFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMDLKESSGKARQHLG 405

  Fly  1445 YCPQFDALLDDLTGREVLRIFCMLRGV----QESRIRQLSEDLAKSFGFMKHIDKQTHAYSGGNK 1505
            |..|..:|..:||..:.||.|..:.|:    |..:|.::||    :||........|.....|.|
E. coli   406 YMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSE----AFGLKSIASHATDELPLGFK 466

  Fly  1506 RKLSTAIAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIVLTSHSMEECEALCTRLA 1570
            ::|:.|.:::..|.:::|||||:|:||..||:.|..:..:.:.|.::::|:|.|:|.| .|.|:.
E. coli   467 QRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVEKGVTVMVTTHFMDEAE-YCDRIG 530

  Fly  1571 IMVNGEFKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYARNPDEQTVPAQMSQRDID 1635
            ::..|:....|:...||.:.:.                            |||..|. |.|..|.
E. coli   531 LVYRGKLIASGTPDDLKAQSAN----------------------------DEQPDPT-MEQAFIQ 566

  Fly  1636 AVKEFVETEYPN 1647
            .:.:: :.|:.|
E. coli   567 LIHDW-DKEHSN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	204/1117 (18%)
ybhF	NP_415315.4	ABC2_perm_RbbA	5..>565	CDD:468210	201/1102 (18%)