Protein Alignment Abca3 and ABCA7

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_190362.2
• Gene: ABCA7 / 823932
• AraportID: AT3G47780
• Length: 935
• Species: Arabidopsis thaliana
• Alignment Length: 966
• Identity: 253/966 - (26%)
• Similarity: 419/966 - (43%)
• Gaps: 192/966 - (19%)

  Fly    13 LLWKNWTLQWNHKWQMVIELVLPAIFSLLLVLVRTLVDTEQKGVRYYN------EQNLT-----D 66
            ||.||.|.|..:.|..:..:::|....:|||:::.|.||:........      |:|..     :
plant    16 LLRKNLTYQKRNLWSNIRLIMIPFYLCILLVIIQILFDTQVNNSADNRCGCECIERNRAGKCQRE 80

  Fly    67 LNLLQH---------SLHRSSYLGKLIALIAPNRR----------RKNGGFSKFEFILCYSPVNP 112
            |..|:|         |:.|......|:.:..|..|          |:.|   .....:.::..|.
plant    81 LCGLEHSKPDQAFFCSIPRPPLWPPLLQIPRPESRDVRGLRDDSCRRTG---SCPVTILFTGNNR 142

  Fly   113 VLKKLVEEAWQSLGKNKICESENATQLELDTVSKNAFA-------------GVQFDDAWANLTEN 164
            .|...|.|   :|..:.:  |.||::: |.|::.|...             |:..:.:..|:...
plant   143 SLGTTVSE---NLFTSSV--SANASEI-LRTLANNVLGTTVEADFTNYLDPGIASNLSIYNIQPR 201

  Fly   165 DPLPNDFHFA-----LRFPAELRTATIAIANTWLTMRLFPTIDLTGPRNEGDD------DGGIPP 218
            ..|...|.|:     |:|..|||  .:..:|.|           |....|.:|      ..|.|.
plant   202 CILNATFPFSFEQPPLKFEKELR--CVQGSNLW-----------TNTSKEVNDKIFKGYKKGNPE 253

  Fly   219 GYL-------------REGF-----------------------LPLQHSL-SMAYLR--QKSGEQ 244
            |.:             |..|                       :|...:| |.|||:  |..|.:
plant   254 GKINEIAAAYDLLNTDRNNFNVHIWYNSTYKDDAGNRLIKLIRVPRSVNLVSNAYLQFLQGPGTR 318

  Fly   245 DLPNVVMKRYPFP--------AYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKE 301
            .|...| |..|.|        |.:..||      ..:.:|||.|    ..|...:..||::.|:.
plant   319 MLFEYV-KEMPKPETSLRLDIASLIGPL------FFTWVILLLF----PVILSSLVYEKQQHLRI 372

  Fly   302 VMKIMGLSNWLHWT---AWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYI 363
            :||:.||.:..:|.   |:|      ||||.:.:..|:....:..:......:::....|..:|:
plant   373 IMKMHGLGDGPYWMISYAYF------LTISVLYVICLMIFGSAIGLKFFRLNSYSIQFVFYFLYL 431

  Fly   364 VSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGI 428
            ...|...|::::.||:..|:...:.:..|.:.:...|.:|...:.| |...||.::.....||.:
plant   432 NLQIALAFLVSSVFSKVKTSTVASYIYVFGSGLLGLFLLNFLIEDS-SFPRGWIIVMELYPGFSL 495

  Fly   429 KLIL------GFEGT--GE-GLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMP 484
            ...|      .|.|.  || |::|.: |...::||      |..:::|...:.:|...|::::
plant   496 YRGLYELAQFAFRGNLRGEDGMKWKD-FGDSAMDD------VFYIIVVEWFLALIAAYYIDKI-- 551

  Fly   485 GSFGVPRPWNF---PF-----------TREFWCGEREYTGVEDIPNGHVEQRDPKAFETEPEGKH 535
             |.....|..|   ||           .|:   |.:....:|. |:...|.:..:....|....|
plant   552 -SSSGRNPLFFLQNPFKKSPSLRRPSLQRQ---GSKVSVDMEK-PDVTHESKKVERLMLESSTSH 611

  Fly   536 IGLQMRHLKK----RFGN--KMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTA 594
             .:...:|||    |.||  |:.|:|||:.:...|...:||.||||||:.|:|:||:..||||||
plant   612 -AIVCDNLKKVYPGRDGNPPKLAVRGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLLKPTSGTA 675

  Fly   595 IINGSDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIEL- 658
            ::.|.||..:::....|:|:||||::|::.::...|:.|:.|:|.|:|..:.|.|.:.||.:.|
plant   676 LVQGLDICNDMDRVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNLKGADLNQAVEESLKSVNLF 740

  Fly   659 -EDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTLLL 722
             ...|:..:.|.||||||:|||..:|.|:.|||..||||:|:||::|:.||.::::.|....::|
plant   741 HGGVADKPAGKYSGGMKRRLSVAISLIGNPKVVYMDEPSTGLDPASRKNLWTVIKRAKQNTAIIL 805

  Fly   723 TTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCETNEVTALLNKYIPG 787
            |||.|:||:.|.||:.|..||.|:|.|....||.:||..|........:.|.| |..|:....|.
plant   806 TTHSMEEAEFLCDRLGIFVDGGLQCIGNPKELKGRYGGSYVFTMTTSSEHEQN-VEKLIKDVSPN 869

  Fly   788 LKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKV 843
            .|....|.....::|| ....:..|:|..:|:......:..:|:..|::|:||:||
plant   870 AKKIYHIAGTQKFELP-KEEVRISEVFQAVEKAKSNFTVFAWGLADTTLEDVFIKV 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	219/812 (27%)
ABCA7	NP_190362.2	rim_protein	<323..>935	CDD:130324	187/637 (29%)
		ABC_subfamily_A	617..838	CDD:213230	94/220 (43%)