Protein Alignment Abca3 and ABCA5

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_001326002.1
• Gene: ABCA5 / 823930
• AraportID: AT3G47760
• Length: 936
• Species: Arabidopsis thaliana
• Alignment Length: 866
• Identity: 237/866 - (27%)
• Similarity: 364/866 - (42%)
• Gaps: 214/866 - (24%)

  Fly   922 MPVFFVVVTILIIKTQGTFQELKPITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGS 986
            :|:|.|........|..:|    |...|..::...|..::..|:......||:|   ::.:.|
plant   193 LPIFNVQPRCTPDTTTFSF----PFRQSPLEFHKEVRCVEGLNLWRNNSIEISN---EIFKGY-- 248

  Fly   987 NYGLELTGTQGFEDYILDLGKTIQVRINSRY-LVAATITESKITAWLNNQ----------ALHTA 1040
                    .||..:.|::       .:.:.| |:...|....:|.|.|:.          .....
plant   249 --------RQGNLEEIIN-------EVAAAYDLMDTDINNFNVTIWYNSTYKGDLRDRRVKYVRV 298

  Fly  1041 PLTVNMVHNAIADKLFGSSVKIQ---VTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVS 1102
            |.:||:|.||..:.|.||..|:.   |...|...|            .|..::|| |...:.|..
plant   299 PRSVNLVSNAYLEFLQGSGTKMLFDFVKEMPKQET------------RLRLEMAS-LIGPIFFTW 350

  Fly  1103 SIYILF------LIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETG 1161
            .|.:||      |:.|::...:::..:.|:....:|:          |..|..:.|:||
plant   351 VILLLFPVMLTSLVYEKQQHLRIIMKMHGLGDGPYWM----------ITYAYFLAISIV------ 399

  Fly  1162 LSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIF---CGMALFIVVVVMSS 1223
                     |.:.|::||.|      |...|||     |...||..||   | :.|.|.:..:.|
plant   400 ---------YIICLMIFGSA------IGLKFFR-----FNDYSIQFIFYFLC-INLQISIAFLVS 443

  Fly  1224 ELFDTKDTADI-----------LG----------------WIF--RIFPHFSLAMSLNKVYTNTA 1259
            ..|...:||.:           ||                ||:  .::|.|||...|.:......
plant   444 SAFSKIETASVAAYLYVFGSGLLGAFLFQFLLEGLSFPRSWIYIMELYPGFSLYRGLYEFSQYAF 508

  Fly  1260 TRNACAKAGALPPILLCELVPQCCNLKPYFAWEE--PGVLPETVYMAVTGVVFFLIIIVLE---- 1318
            .||.....|                    ..|::  ...:.|..|:.:  |.:|:.:|...
plant   509 KRNLNGSGG--------------------MKWKDFNDSAMEEIFYIII--VEWFVALIAAYYTDK 551

  Fly  1319 ---------FRLINELMFKIRQLISKPPPPPTEGQLDD--------DVANERERILQMSSNELAT 1366
                     |.|.|:..||     ..|.|...:.|:..        |||:||.::.|:.......
plant   552 ISSSGIDPFFFLKNQNPFK-----KSPSPYGLQRQVSAIAIEMEKLDVAHERVKVEQLMLETSTG 611

  Fly  1367 KNLVLDRVTKYY------GQFMAVNQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAA 1425
            ..:|.|.:.|.|      .|.|||..:||.|...||||:||.||||||:...||||..:.:||||
plant   612 HAIVCDNLKKVYPCRDGNPQKMAVRGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLMKPTSGAA 676

  Fly  1426 YVQGLSLESNMNSIYKMIGYCPQFDALLDDLTGREVLRIFCMLRGVQESRIRQLSEDLAKSFGFM 1490
            :|.||.:..:|:.:|..||.|||.|.|.:.|||||.|..:..|:.::.|.:.|..|:..||....
plant   677 FVHGLDICKDMDIVYTSIGVCPQHDLLWETLTGREHLLFYGRLKNLKGSDLDQAVEESLKSVNLF 741

  Fly  1491 KH--IDKQTHAYSGGNKRKLSTAIAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIV 1553
            :.  .||....||||.||:||.||::||||.|:|:|||:||:|||:||.||..:.|.::. .:|:
plant   742 RGGVADKPAGKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRRSLWTAIKRAKNH-TAII 805

  Fly  1554 LTSHSMEECEALCTRLAIMVNGEFKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYAR 1618
            ||:|||||.|.||.||.|.|:|..:|:|:.:.||                      ||..|.|..
plant   806 LTTHSMEEAEFLCDRLGIFVDGRLQCVGNPKELK----------------------ARYGGSYVL 848

  Fly  1619 NPDEQTVPAQMSQRDIDAVKEFVETEYPNSILQEEYQGILTFYIPLTGVKWSRIFGLMESNRDQL 1683
            .   .|.|:: .::|::.:   |:...||:.......|...|.||...|:.|.:|..:|..:|..
plant   849 T---MTTPSE-HEKDVEML---VQDVSPNAKKIYHIAGTQKFEIPKEEVRISEVFQAVEKAKDNF 906

  Fly  1684 NVEDYSVSQTTLEEIFLEFAK 1704
            .|..:.::.||||::|::.|:
plant   907 RVFAWGLADTTLEDVFIKVAR 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	237/866 (27%)
ABCA5	NP_001326002.1	rim_protein	<345..>936	CDD:130324	198/677 (29%)
		ABC_subfamily_A	618..839	CDD:213230	102/221 (46%)