Protein Alignment Abca3 and ABCA3

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_190358.3
• Gene: ABCA3 / 823928
• AraportID: AT3G47740
• Length: 932
• Species: Arabidopsis thaliana
• Alignment Length: 908
• Identity: 243/908 - (26%)
• Similarity: 378/908 - (41%)
• Gaps: 203/908 - (22%)

  Fly   880 IFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFV-VVTILI---IKTQGTF 940
            :|:.|...| |..|..|    :|.:.|.....:.|..|..|::...|. ..|..:   |.:.|:.
plant   136 LFTGNNHSL-GAVLSRN----LLRRPFAMNSSDLLFSLANNVLATTFKGSATNYLDAGIVSDGSI 195

  Fly   941 QELKP-------ITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGSNYGLELTGTQGF 998
            ..::|       .:||:.|.||..| .|...||.          .:|.|:......|||     |
plant   196 YNIQPRCPPNSNFSISIGQSPLNFT-KDMRCVQG----------LNLWRNNSIEVNLEL-----F 244

  Fly   999 EDYILDLGKTIQVRINSRY-LVAATITESKITAWLN--------NQALHT--APLTVNMVHNAIA 1052
            |.|.......:...|.:.| |....:|...:..|.|        ||....  .|..||.|.||..
plant   245 EGYHKGNSDGMINEIVAAYDLFDTNMTNFNVNIWFNATYKDEARNQPYKVVRVPRLVNWVSNAYL 309

  Fly  1053 DKLFGSSVKIQ---VTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILF------ 1108
            ..|.|...|:.   |...|.|.|            .|...:|| |...:.|...|.:|.
plant   310 QYLQGPRTKMLFEFVKEMPKPET------------KLRLDIAS-LIGPIFFTWVILLLLPVILNS 361

  Fly  1109 LIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYL 1173
            |:.|::.|.:::..:.|:....:|    |..:|.::                .||||     |.:
plant   362 LVYEKQQRLRIIMKMHGLGDGPYW----IISYAYFL----------------ALSTF-----YII 401

  Fly  1174 LLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFDTKDTADI---- 1234
            .|::||..:....::::.|..:.:..|..::         |.|.:..:.|..|...:||.:
plant   402 FLMIFGSVIGLKFFLLNDFSLQFSFYFVYIN---------LQISIAFLLSSAFSKVETASVAAYL 457

  Fly  1235 -------LG----------------WIF--RIFPHFSLAMSLNKVYTNTATRNACAKAGALPPIL 1274
                   ||                |||  .::|.|||...|.:...|....|...|.|
plant   458 YVFGSGLLGMFLFQFLLEGLSFPRRWIFVMELYPGFSLYRGLYEFSQNAYQGNLNGKDG------ 516

  Fly  1275 LCELVPQCCNLK-PYFAWEEPGVLPETVYMAVTGVVFFLIIIV-------------LEFRLINEL 1325
                      :| .||:   ...:.|..|:.:  |.:|:.:|.             |.|.|.|:.
plant   517 ----------MKWKYFS---DNAIDEVFYIII--VEWFVALIATYYIDKMSSSGKDLLFFLKNQN 566

  Fly  1326 MFKIRQLISKPPPPPTEGQLDDDVANERERILQMSSNELATKNLVLDRVTKYY-GQ-----FMAV 1384
            .|||...:.|.....:......||.:|.|::.|:......:..:|.|::.|.| |:     ..||
plant   567 PFKISHSLQKQVSAISVEMEKLDVIHESEKVAQLMLESSTSHAIVCDKLRKVYPGRDGNPPKKAV 631

  Fly  1385 NQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAAYVQGLSLESNMNSIYKMIGYCPQF 1449
            ..:||.|...||||:||.||||||:...||||..:.:||||:||||.:..:|:.:|..:|.|||.
plant   632 RVLSLAVPSGECFGMLGPNGAGKTSFINMMTGLVKPTSGAAFVQGLDICKDMDRVYTSMGVCPQH 696

  Fly  1450 DALLDDLTGREVLRIFCMLRGVQESRIRQLSEDLAKSFGFMKH---IDKQTHAYSGGNKRKLSTA 1511
            |.|.:.|||||.|..:..|:.::...:.|..|:..:|.... |   .||....||||.||:||.|
plant   697 DLLWETLTGREHLLFYGRLKNLKGVDLNQAVEESLRSVNLF-HGGVADKPAGKYSGGMKRRLSVA 760

  Fly  1512 IAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIVLTSHSMEECEALCTRLAIMVNGE 1576
            |::||:|.|:|:|||:||:|||:|:.||.::...: ...:|:||:|||||.|.||.||.|.|:|.
plant   761 ISLIGNPKVVYMDEPSTGLDPASRKNLWTVIKNAK-RHTAIILTTHSMEEAEFLCDRLGIFVDGR 824

  Fly  1577 FKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYARNPDEQTVPAQMSQRDIDAVKEFV 1641
            .:|||:.:.||.::....:|.:                            ...|:.:.| |:..|
plant   825 LQCIGNPKELKGRYGGSYVLTM----------------------------TTSSEHEKD-VEMLV 860

  Fly  1642 ETEYPNSILQEEYQGILTFYIPLTGVKWSRIFGLMESNRDQLNVEDYSVSQTTLEEIFLEFAK 1704
            :...||........|...|.||...|:.|.:|.::|..:....|..:.::.||||::|::.|:
plant   861 QEVSPNVKKIYHIAGTQKFEIPKDEVRISEVFQVVEKAKSNFKVFAWGLADTTLEDVFIKVAR 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	243/908 (27%)
ABCA3	NP_190358.3	rim_protein	<303..>932	CDD:130324	199/720 (28%)
		ABC_subfamily_A	614..835	CDD:213230	98/222 (44%)