Protein Alignment Abca3 and ABCA2

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_190357.2
• Gene: ABCA2 / 823927
• AraportID: AT3G47730
• Length: 983
• Species: Arabidopsis thaliana
• Alignment Length: 927
• Identity: 243/927 - (26%)
• Similarity: 415/927 - (44%)
• Gaps: 174/927 - (18%)

  Fly     9 KFVLLLWKNWTLQWNHKWQMVIELVLPAIFSLLLVLVRTLVDTEQKGVRYYNEQNLTDLNLLQHS 73
            ::..|..||..|.|..|....::|.....|.||:..::.                     .::.|
plant    13 QYTALFKKNLLLSWRSKRATFLQLFASFFFILLIFCIQA---------------------AMEKS 56

  Fly    74 LHRSSYLGKL---IALIAPNRRRKNGGFSKFEFILCYSPVNPVLKKL------VEEAWQSLGKNK 129
            ...|:.|..:   .|||:|                   |:.|...|.      .:..|.....:|
plant    57 FASSTALKTVTDPTALISP-------------------PIPPCEDKFFVNLPCYDFVWSGNRSSK 102

  Fly   130 ICESENATQLELDTVSKN------------AFAGVQFDDAWANLTENDPL--PNDFHFALRFPAE 180
            :.:..||       :.||            :|...:..|.|  |..| ||  |...||.
plant   103 VTQIVNA-------IMKNNPGRSIPIEKVRSFVDPEAVDTW--LMAN-PLLVPGALHFI------ 151

  Fly   181 LRTATIAIANTWLTMRLFPTIDLTGPRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGEQD 245
            .|.||  :.:..:.....|.::    |...:|     |.:..:  :|||.:......|...|:.:
plant   152 ERNAT--VISYGIQTNSTPEMN----RGRFED-----PTFKFQ--IPLQIAAEREIARSLIGDPN 203

  Fly   246 LPNVV-MKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTY-----------ITKYITAEKEKQ 298
            ...|| .|.:|.|.             :..|:.|..|.|..:           |:..|| |||.:
plant   204 FNWVVGFKEFPHPT-------------IEAIVALDTIGPTFFLAVAMFGFVLQISSLIT-EKELK 254

  Fly   299 LKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFL-IIY 362
            |::.|.:||:.:..:|.:|.....|:..||| |:.:|..:.:..|..:   .|...:||.| :::
plant   255 LRQAMTMMGVFDTAYWLSWLTWEGILTAISA-LLTVLFGMMFQFDFFL---KNSFPVVFLLFMLF 315

  Fly   363 IVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKL---GWSLISNTAM 424
            ..:.|...||::.|.|::::|..|...::.:.::....|.:.:......|::   .|||......
plant   316 QFNLIGLAFMLSAFISKSTSATTVGFFVFLVGFVTQLATSSGFPYAKKYSRMIRALWSLFPPNTF 380

  Fly   425 GFGIKLILGFEGTGE--GLQWSNFFTPVSVDDT---LTLGAVMIMMLVSCVIYMIICLYVEQVMP 484
            ..|:||:.....|.:  |:.||........|||   ||:..:.:.:|.:..::.::.||.:.:.|
plant   381 SQGLKLLADATSTPQDPGISWSKRAECGPNDDTGCVLTINDIYLWLLGTFFLWFVLALYFDNITP 445

  Fly   485 GSFGVPRPWNFPFTREFWCGER----EYTGVEDI-----PNGHVEQRDPKAFETEP-------EG 533
            .:.||.:...:.....:|.|:.    |..|:...     |..|:...|....|.|.       ||
plant   446 NASGVRKSIFYFLKPGYWTGKGGNRVEEGGICSCIGSVPPVDHITPDDEDVLEEETLVKQHSMEG 510

  Fly   534 ---KHIGLQMRHLKK------RFG----NKM----VVKGLSMNMFEDEITVLLGHNGAGKTTTIS 581
               .::.:|:|.|.|      :||    .|.    .:|||.||:.:|::..|||.|||||||||:
plant   511 LVDPNVAVQIRGLAKTYPGTTKFGCCKCKKTSPFHALKGLWMNIAKDQLFCLLGPNGAGKTTTIN 575

  Fly   582 MLTGMFPPTSGTAIINGSDIRTNI--EGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKA 644
            .|||:||.|.|.|:|.|:.||:::  ...|..:|:|||.::|:|.:|...|::.|:.:|||...:
plant   576 CLTGLFPVTGGDALIYGNSIRSSVGMSNIRKMIGVCPQFDILWDALSGEEHLKLFASIKGLPPSS 640

  Fly   645 VEQEVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWD 709
            :...|.|.|..::|.:...:.:...||||||:|||..:|.||.|:|..|||::||||..||.:||
plant   641 INSMVEKSLAEVKLTEAGKIRAGSYSGGMKRRLSVAVSLIGDPKLVFLDEPTTGMDPITRRHVWD 705

  Fly   710 LLQQEKVGRTLLLTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGY--RLICVKRDD- 771
            ::|:.|.||.::||||.|:|||:|.|||.||..|.|:|.|||..||.::|:|:  .:..|:.::
plant   706 IIQETKKGRAIILTTHSMEEADILSDRIGIMAKGRLRCIGTSIRLKSRFGTGFIANISFVESNNH 770

  Fly   772 -----CETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGV 831
                 .::.|......|....:||..:..|.:::.:|..........|.:|:::.:|..::...:
plant   771 NGEAGSDSREPVKKFFKDHLKVKPIEENKAFMTFVIPHDKENLLTSFFAELQDREEEFGISDIQL 835

  Fly   832 GITSMEEVFMKVGAEKD 848
            |:.::||||:.:..:.:
plant   836 GLATLEEVFLNIARKAE 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	219/790 (28%)
ABCA2	NP_190357.2	rim_protein	<186..>861	CDD:130324	199/685 (29%)
		ABC_subfamily_A	518..751	CDD:213230	103/232 (44%)