|
Fly 135 NATQL--ELDTVSKNAFAGVQF--------------DDAWANLTEND------------------ 165
|.|.| :|||:...|...:|| :::..|.|.|.
Rat 557 NGTALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRK 621
Fly 166 --PLPNDFHFALRFPAELRTATIAIANT-WLTMRLFPTIDLTGPRNEGDDDGGIPPGYLREGFLP 227
.||...|:.:|..:.....|..|... | ..|.:.|| ..|...||:.
Rat 622 DGSLPPHVHYKIRQNSSFTEKTNEIRRAYW---------------RPGPNTGG--RFYFLYGFVW 669
Fly 228 LQHSLSMAYLRQKSGEQDL-PNVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYI 291
:|..:..|.:....|...: |...::.:|:|.|..|..|..:..:|.|.:::|::|......::|
Rat 670 IQDMIERAIINTFVGHDVVEPGNYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHI 734
Fly 292 TAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALV 356
.||||.:||||||.|||:|.:||.|||:..|:.|:||...:..::|.. .||.|::...:.
Rat 735 VAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTAILKYG-----QVLMHSHVLIIW 794
Fly 357 FFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTI----NSYDDLSLSSKLGWS 417
.||.:|.|::|.|||:::..:|:|..|:|..|:|:|::|:||.:.. .::|.::...|...|
Rat 795 LFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIAS 859
Fly 418 LISNTAMGFGIKLILGFEGTGEGLQWSNFF-TPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQ 481
|:|.||.|.|.|....:|..|.|:||..|. :||..||...|.|| .|::|..|:|.::..|:|.
Rat 860 LMSTTAFGLGSKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAV-TMLMVDTVVYGVLTWYIEA 923
Fly 482 VMPGSFGVPRPWNFPFTREFWCGE-REYTGVEDIPNGH--------------VEQR---DPKAFE 528
|.||.:|:||||.||..:.:|.|. |..|.....|..| :|.| :.:..|
Rat 924 VHPGMYGLPRPWYFPLQKSYWLGSGRTETWEWSWPWAHAPRLSVMEEDQACAMESRHFEETRGME 988
Fly 529 TEPEGKHIGLQMRHLKKRFGN--KMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTS 591
.||....:.:.:..|.|.:.| |:.:..||:|::|:::...|||||||||||:|:|||:|||||
Rat 989 EEPTHLPLVVCVDKLTKVYKNDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTS 1053
Fly 592 GTAIINGSDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMI 656
|:|.|.|.||||.::..|.:||:|||||||||:::|..|:.|:||:|.:..:.:.:|:.|.::.:
Rat 1054 GSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDQLTVEEHLWFYSRLKSMAQEEIRKEMDKMIEDL 1118
Fly 657 ELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTLL 721
||.:|.:.....|||||||||||..|..|.::.::.|||::|:||.|||.:|||:.:.|.|||:|
Rat 1119 ELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTIL 1183
Fly 722 LTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKR----------------- 769
|:||.|||||:|||||||:..|:|||.|:..|||..||.||||..|||
Rat 1184 LSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGAYGDGYRLTLVKRPAEPGTSQEPGMASSPS 1248
Fly 770 -----DDCETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAK--FEEMFGQLEEQSDELHLN 827
.:|...:|:..:.|::.......|...||||.||..|..| ||.:|.|||...|.|||:
Rat 1249 GRPQLSNCSEMQVSQFIRKHVASSLLVSDTSTELSYILPSEAVKKGAFERLFQQLEHSLDALHLS 1313
Fly 828 GYGVGITSMEEVFMKVGAE----KDNTGNIKD-QHEIMNGGSGF--------------------- 866
.:|:..|::||||:||..| :::..::|: :.:.:.|..|.
Rat 1314 SFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDALPGAEGLTAVESQAGNLARCSELAQSQA 1378
Fly 867 -----------RGED---------------------DNESVQSDGI-----FSENRRLLQGLQLL 894
||:: |:.|:|...: ..:..|.|:|..|.
Rat 1379 SLQSASSVGSARGDEGAGYTDGYGDYRPLFDNLQDPDSVSLQEAEMEALARVGQGSRKLEGWWLK 1443
Fly 895 SNQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFVVVTILIIKTQGTFQELKPITISLTQY------ 953
..|:..:|:|:|....||...|..|.::|.|||.|.:.:..:.....:|.|:.:|.:||
Rat 1444 MRQFHGLLVKRFHCARRNSKALCSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQP 1508
Fly 954 -----PLA-------------------------------VTVLDRS----------NVQNGTGYE 972
|.| .|.:.:| |:.:|....
Rat 1509 RGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPMLNLSSGESRL 1573
Fly 973 IANKYEDLARSYGSNYGLELT-------------------------------------------- 993
:|.::.|.........||.|:
Rat 1574 LAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPLSPDEDSLLAWNTSLPPTAGPETWTWAPS 1638
Fly 994 ----------------GTQGF-----------------------------EDYIL---------- 1003
|| || .:|:|
Rat 1639 LPRLVHEPVRCTCSAQGT-GFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHR 1702
Fly 1004 -------DLGKTIQVRINSRY-LVAATITESKITAWL-NNQALHTAPLTVNMVHNAI------AD 1053
::.|:|...|.:|. |:...|...::...| ||:..|:.|..:|.::||| ..
Rat 1703 YGAITFGNIQKSIPAPIGTRTPLMVRKIAVRRVAQVLYNNKGYHSMPTYLNSLNNAILRANLPKS 1767
Fly 1054 KLFGSSVKIQVTNAPLPYTTSTL-LSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRA 1117
|...::..|.|||.|:..|:::| |..|..|.:: .:|..:...|.||.:.:::||:.|:.::|
Rat 1768 KGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDV--VIAIFIIVAMSFVPASFVVFLVAEKSTKA 1830
Fly 1118 KLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAV 1182
|.||||.|.....:||:.::.|..:|:|.|...:|.:..|.....::.........|.||:|:::
Rat 1831 KHLQFVSGCNPVIYWLANYVWDMLNYLVPATCCIIILFVFDLPAYTSPTNFPAVLSLFLLYGWSI 1895
Fly 1183 LPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELF----DTKDTADILGWIFRIFP 1243
.|.:|..|.:|..|::.:..:.::|:|.|:...:...:: :|| |.|.....|...|.|||
Rat 1896 TPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLL--QLFEHDKDLKVVNSYLKSCFLIFP 1958
Fly 1244 HFSLAMSLNKVYTNTATRNACAKAGALPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGV 1308
:::|...|.::..|.......||.| |...:|..|.|:. |....|.|.|.|.
Rat 1959 NYNLGHGLMEMAYNEYINEYYAKIG------------QFDKMKSPFEWDI--VTRGLVAMTVEGF 2009
Fly 1309 VFFLIIIVLEFRLINELMFKIRQLISKPPPPPTEGQLDD-DVANERERILQMSSNELATKNLVLD 1372
|.|.:.|:.::..:.: .:..|..|:...|| |||:||:|:|:..::....| ::
Rat 2010 VGFFLTIMCQYNFLRQ---------PQRLPVSTKPVEDDVDVASERQRVLRGDADNDMVK---IE 2062
Fly 1373 RVTKYY-----GQFMAVNQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAAYVQGLSL 1432
.:||.| |:.:||:::.|.|:..||||||||||||||:||||:||||..:.|.|:|.|.|:
Rat 2063 NLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSV 2127
Fly 1433 ESNMNSIYKMIGYCPQFDALLDDLTGREVLRIFCMLRGVQESRIRQLSEDLAKSFGFMKHIDKQT 1497
..::..:.:.:|||||||||.|:||.||.|:::..|||:......|:.....:.....|..||..
Rat 2128 LKDLLQVQQSLGYCPQFDALFDELTAREHLQLYTRLRGIPWKDEAQVVRWALEKLELTKCADKPA 2192
Fly 1498 HAYSGGNKRKLSTAIAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIVLTSHSMEEC 1562
.:||||||||||||||:||.|:.|:||||||||||.|||.|||::..:..:|:|:||||||||||
Rat 2193 GSYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEEC 2257
Fly 1563 EALCTRLAIMVNGEFKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYARNPDEQTVPA 1627
||:||||||||||..:|:||.|||||:|..|.::.::.:
Rat 2258 EAVCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTK-------------------------- 2296
Fly 1628 QMSQRDIDAVKEFVETEYPNSILQEEYQGILTFYIPLTGVKWSRIFGLMESNRDQLNVEDYSVSQ 1692
|.:::..|..|....:|.::|:|.:...:.:.:....:..:::|..||.....|.:|||||||
Rat 2297 --SSQNVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEHVVGVLGIEDYSVSQ 2359
Fly 1693 TTLEEIFLEFAKYQREDTRANQ 1714
|||:.:|:.|||.|.::....:
Rat 2360 TTLDNVFVNFAKKQSDNVEQQE 2381
| 
