Protein Alignment Abca3 and CG11147

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Alignment Length: 865
• Identity: 177/865 - (20%)
• Similarity: 310/865 - (35%)
• Gaps: 249/865 - (28%)

  Fly   538 LQMRHLKKRFGN----KMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIING 598
            :::|:..|.:|:    |:|:..|:||:....|..|||.:|.||||.:|.:.|......|..::.|
  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLG 68

  Fly   599 S---DIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIELED 660
            :   :..:.:.|:|  :|..||...|.:||:|...|.:|.|:.||..:.: :|..|.||.:....
  Fly    69 AKPGEPGSGVPGSR--VGFMPQEIALVEEMTVKETIFYFGRIYGLTDERI-REKFKLLKELLQLP 130

  Fly   661 KANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTL--LLT 723
            .|.....:.|||.:|:||..||:..|.::::.|||:.|:||..|.::||.|.:......|  ::|
  Fly   131 PARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIIT 195

  Fly   724 THFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGS----GYRLICVKRDDCETNEVTALL--- 781
            ||:::||. ..:.|.:|.:|.|..:.|...:..::|:    ...||..:|...| :|:..::
  Fly   196 THYIEEAK-QANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNE-DELAQIMDHN 258

  Fly   782 -NKYIPG--LKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKV 843
             |:.:|.  |.||.....|.:  :|:.....|||...:                  :.:::|
  Fly   259 KNQALPAAVLPPEVIDTHEPN--MPEKQPIPFEEPLNE------------------NRKKIF--- 300

  Fly   844 GAEKDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGIFSENRRLLQGLQLLSNQWKAMLLKKFLY 908
                                                 |:...|:           ||::.|.|:.
  Fly   301 -------------------------------------FTTKGRV-----------KALMTKNFVQ 317

  Fly   909 TWRNKLLLLIQNIMPVFFVVVTILIIKTQGTFQELKPITISLTQYPLAVTVLDRSNVQNGTGYEI 973
            .:|....::...:.|:                       |.||.:.||:.       :..|..||
  Fly   318 LFRQPSGIIFMLLFPI-----------------------IQLTCFYLAIG-------KTPTNLEI 352

  Fly   974 ANKYEDLARSYGSNYGLELTGTQGFED------------YILDLGKTIQVRINSRYLV--AATIT 1024
             ..|.....:||..:...|.......|            ||..||..:..|   :|..  |..:.
  Fly   353 -GVYSGEVENYGECFDENLVTVYKDSDNESCLFNKLSCRYIRVLGDDVATR---KYYASEADALN 413

  Fly  1025 ESKITAWLNNQALHTAPLTVNMVHNAIADKLFGS---------SVKIQVTNAPLPYTTSTLLSQL 1080
            ::|....:.  .||.|....:.:.:.:.|.:..|         |:.|.:|:..:.|     ..|.
  Fly   414 DAKRATTVG--YLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQQVAY-----FMQR 471

  Fly  1081 STGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIV 1145
            ...:...|.:.|.:..|.  ||:..:...::.:|      ...|...:          :|..|..
  Fly   472 KLRDKFSTFMRSVVKDCN--VSTAIVDLPVQFQE------PIFGSTDI----------EFQQYCA 518

  Fly  1146 TALIVVITIVCFQET----------------------GLST----FGELGRYYLLLLLFGFAVLP 1184
            ..  ||:|:|.|..|                      |:|.    :..|....:::.|..|.|:.
  Fly   519 PG--VVMTMVFFLATLMTAAVFISERMDGIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVIM 581

  Fly  1185 FI-YIMSLFFREPATGFARVSIVNIFCGM--ALFIVVVVMSSELFDTKDTADI--------LGWI 1238
            :| .:...:.....|....:..:..||||  .|||.|...|....:...|...        |.|.
  Fly   582 YIGLVFDTYNNGDTTTLIGLLTLTAFCGMLFGLFISVFCKSHTEANFVATGAFYPMIILCGLLWP 646

  Fly  1239 FRIFPHF--SLAMSLNKVYTNTATRNACAKAGALPPILLCELVPQCCNLKPYFAWEEPGVLPETV 1301
            ....|.|  .|.|.|.....:.:.||...|                       .|   .:..|.|
  Fly   647 LESMPQFLQDLVMVLPFTIPSISARNVIEK-----------------------GW---SITHEKV 685

  Fly  1302 Y-----MAVTGVVFFLIIIV 1316
            |     ||...::||::.::
  Fly   686 YNGFLVMAGWTIIFFVLCLI 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	177/865 (20%)
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	73/244 (30%)
		ABC2_membrane_3	322..702	CDD:463674	83/466 (18%)
		YadH	513..710	CDD:440604	44/221 (20%)