Protein Alignment Abca3 and osy

DIOPT Version :10

• Sequence 1: NP_608445.2
• Gene: Abca3 / 33103
• FlyBaseID: FBgn0031170
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: XP_312290.4
• Gene: osy / 1273324
• VectorBaseID: AGAMI1_006800
• Length: 776
• Species: Anopheles gambiae
• Alignment Length: 898
• Identity: 178/898 - (19%)
• Similarity: 335/898 - (37%)
• Gaps: 257/898 - (28%)

  Fly   525 KAFETEPEGKHIGLQ----MRHLKKRFGNK----MVVKGLSMNMFEDEITVLLGHNGAGKTTTIS 581
            |.|.::|....|..|    :|...|.:|.|    :::.||:|.:.:..|..|||.:|.||||.:|
Mosquito    32 KKFMSQPSTVAIRRQQAVCVRRAHKIYGTKKNPNVILDGLNMTVPKGSIYGLLGASGCGKTTLLS 96

  Fly   582 MLTGMFPPTSGTAIING---SDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGK 643
            .:.|.....||...:.|   ....:.:.|.|  :|..||...|:.|.::...:.:|..:.|:...
Mosquito    97 CIVGRRRLNSGEIWVLGGRPGSRGSGVPGPR--VGYMPQEVALYGEFTIRETLIYFGWIYGMTTD 159

  Fly   644 AVEQEVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLW 708
            .|:::.....|:::|.:.:....: ||||.:|::|:..||..:.::::.|||:.|:||..|:.:|
Mosquito   160 QVDEKTDFLCKLLQLPNASRFVKN-LSGGQQRRMSLAAALLNEPELLILDEPTVGVDPVLRQSIW 223

  Fly   709 D-LLQQEKVGR-TLLLTTHFMDE---ADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVK 768
            | |::..|.|. |:::|||:::|   |.|:|    :|..|:...:.:...|..||
Mosquito   224 DHLVEITKSGNTTVIVTTHYIEETRQAHVIG----LMRGGKFLAEESPADLLAQY---------- 274

  Fly   769 RDDCETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGI 833
              ..|:.|                |:..:||. |.:....:...:..::.|.          |.|
Mosquito   275 --QAESLE----------------DVFLKLSV-LQNMGKRRRSSIAQEVVEH----------VRI 310

  Fly   834 TSMEEVFMKVGAEKDNTGNIKDQHEIMNGGSGFRGEDDNESVQS---DGIFSE------------ 883
            .::....:.:..|:|        |..::|..|     ||.|:.|   |.:..|
Mosquito   311 PAISNPALDLSPEED--------HGEISGEFG-----DNISMSSRGPDAVTPEIQAPPLPPEEDT 362

  Fly   884 NRRLLQGLQLLS-NQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFVVVTILII-------KTQGTF 940
            ...|::.|:.:. |..:|::.|.||:.|||..::.....:||..:::....|       |.....
Mosquito   363 KTPLVEYLKFIKPNHMRALIWKNFLWMWRNVGVMAFIIGLPVAQIILFCWAIGHDPVGLKLAVAN 427

  Fly   941 QELKPITISLTQYPLAVTVLDRSNVQNGTGYEIAN-KYEDLAR-------------------SYG 985
            .||:....|....|          |..|..|.:.: :|.:..:                   |.|
Mosquito   428 YELEEAGYSFQDCP----------VYPGCNYSLLSCRYMEFLKNRSVVLELFSSESDALQQVSRG 482

  Fly   986 SNYGLELTGTQGFEDYIL---DLGKTI-QVRINSRYLVAATITESKITAWLNNQALHTAPLT--- 1043
            :.:| .|.....:.|.::   :.|:.: ...|:|..|.        :|..::||.:.|....
Mosquito   483 NAWG-ALVFASNYSDSLVERTERGRDVDDFTIDSANLA--------VTMDMSNQQIGTLLYRDIQ 538

  Fly  1044 ---VNMVHNAIADKLFGSSVKIQVTNAPLPYTTSTLLSQLSTGN---NLGTQLASNLCFCMCFVS 1102
               .:.:.|.:.|      .::..:|..:|:..:..:    .|:   |.....|..:...:.|..
Mosquito   539 YAYFDFIENILID------CEVNPSNGRIPFQWNKPV----YGDRKPNFTDFAAPGVILTIIFFL 593

  Fly  1103 SIYI---LFLIKERESRAK--LLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGL 1162
            |:.:   ..||:..|...:  |:..:.|:::           ..|::.|..:|    :|||..
Mosquito   594 SVALTSGAMLIERNEGILERCLVSGITGIEI-----------LFSHVTTQFLV----MCFQTA-- 641

  Fly  1163 STFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFD 1227
                       |:::|.|:|      .:|..|........::|:...|||. |..||..|.:
Mosquito   642 -----------LVMVFSFSV------FNLTNRGDIVWVILLTILTGLCGMC-FGFVVSCSCD--- 685

  Fly  1228 TKDTADILGWIFRIFPHFSLAMSLNKVYTNTATRNACAKAGALPPILLCELVPQCCNLKPYF--- 1289
                                         |..:....|....||.::||.::.....:.|..
Mosquito   686 -----------------------------NERSATYMAMGSFLPIVMLCGIIWPIEGMHPLVRVF 721

  Fly  1290 -------------------AW--EEPGVLPETVYMAVTGVVFFLI-IIVLEFR 1320
                               .|  |:|.|.......|:..|:|..| |::|:|:
Mosquito   722 SVFLPLTKSTESLRSILQRGWLIEDPNVYIGFASTAIWIVIFLTISILLLKFK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abca3	NP_608445.2	rim_protein	<137..1708	CDD:130324	178/898 (20%)
osy	XP_312290.4	CcmA	51..286	CDD:440746	69/269 (26%)
		YadH	577..772	CDD:440604	44/261 (17%)