DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1494 and mglA

DIOPT Version :9

Sequence 1:	NP_001259763.1	Gene:	CG1494 / 33102	FlyBaseID:	FBgn0031169	Length:	1695	Species:	Drosophila melanogaster
Sequence 2:	NP_416654.1	Gene:	mglA / 949036	ECOCYCID:	EG10592	Length:	506	Species:	Escherichia coli

Alignment Length:	454	Identity:	93/454 - (20%)
Similarity:	170/454 - (37%)	Gaps:	121/454 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   524 VNSTKIYEVEPSHRRFKLKIKKLCKRFATNDRP---ALNLFSWNVYENEVTVLMGHNGCGKSTLL 585
            |:||     .||...:.|::..:.|.|     |   ||:..:..|..:.:..|||.||.||||||
E. coli     2 VSST-----TPSSGEYLLEMSGINKSF-----PGVKALDNVNLKVRPHSIHALMGENGAGKSTLL 56

  Fly   586 KILAGLVEPSRGTVMISSHNIQTERKAASMELGIAFGHDML-----------------LTGFTVI 633
            |.|.|:.:...||::.....|.......::|.||:..|..|                 .|....:
E. coli    57 KCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFV 121

  Fly   634 DYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILI 698
            |..:.....|.:.:.::||....             .|:.||:...:.::.|..||..|:.|:::
E. coli   122 DQDKMYRETKAIFDELDIDIDPR-------------ARVGTLSVSQMQMIEIAKAFSYNAKIVIM 173

  Fly   699 DDVHSDLDKRTQSLVWNLINEEKSKRT-IILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKN 762
            |:..|.|.::..:.::.:|.:.|.:.. |:.:|:.......:.|.:.::.:|:  ...|:|
E. coli   174 DEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQ--WIATEP---- 232

  Fly   763 MYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENM 827
                                        :..:::::.|...|...|..:|.|         :||
E. coli   233 ----------------------------LAGLTMDKIIAMMVGRSLNQRFPD---------KEN- 259

  Fly   828 QQLGVVSFRIRD-TSMEEIFLRFGCEDNDQSGAFQSHENAQVL---------LEEYYSTLAEANE 882
             :.|.|...:|: ||:.:..:|      |.|  |..|: .::|         ..:...||....|
E. coli   260 -KPGEVILEVRNLTSLRQPSIR------DVS--FDLHK-GEILGIAGLVGAKRTDIVETLFGIRE 314

  Fly   883 KGRRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFE------VLAMALVAVCTFSSIFIYGKNYE 940
            |...|    ..|||:.:.......|..|...|:.|      :.|...:.   |:|:....:||:
E. coli   315 KSAGT----ITLHGKQINNHNANEAINHGFALVTEERRSTGIYAYLDIG---FNSLISNIRNYK 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468
		CcmA	541..848	CDD:224054	65/328 (20%)
		ABC_subfamily_A	541..761	CDD:213230	53/240 (22%)
		ABC2_membrane_3	911..>1189	CDD:289468	7/36 (19%)
		ABC2_membrane	<1080..>1188	CDD:304374
		ABC_subfamily_A	1370..1577	CDD:213230
		PRK14255	1371..1586	CDD:172743
mglA	NP_416654.1	PRK10982	16..506	CDD:182880	87/435 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X215
SwiftOrtho	1	1.000	-	-
	3	2.910