DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1494 and potG

DIOPT Version :9

Sequence 1:	NP_001259763.1	Gene:	CG1494 / 33102	FlyBaseID:	FBgn0031169	Length:	1695	Species:	Drosophila melanogaster
Sequence 2:	NP_415376.4	Gene:	potG / 945476	ECOCYCID:	EG11630	Length:	377	Species:	Escherichia coli

Alignment Length:	411	Identity:	94/411 - (22%)
Similarity:	172/411 - (41%)	Gaps:	78/411 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   541 LKIKKLCKRFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHN 605
            |:|:.|.|.:  :.:.|::..|..:|:.|:..|:|.:||||||||::|||..:||.|.:|:...:
E. coli    20 LEIRNLTKSY--DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVD 82

  Fly   606 IQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNN----IEIDGQSNYFLNVLQIGG 666
            : ::.......:.:.|....|....||...:.|     ||..:    .||..:.|..|.::.:..
E. coli    83 L-SQVPPYLRPINMMFQSYALFPHMTVEQNIAF-----GLKQDKLPKAEIASRVNEMLGLVHMQE 141

  Fly   667 LKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDK----RTQSLVWNLINEEKSKRTII 727
            ...::...|:......|::..:......::|:|:....|||    |.|..|.:::  |:...|.:
E. coli   142 FAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDIL--ERVGVTCV 204

  Fly   728 LVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMP 792
            :|::....|..:|.|:|||:.|:....| :|  :.:|.|       ....|.. |..|.:|.:
E. coli   205 MVTHDQEEAMTMAGRIAIMNRGKFVQIG-EP--EEIYEH-------PTTRYSA-EFIGSVNVF-- 256

  Fly   793 NMSIERDIGYKVTFVLENKFED----QFPMLIDDLEENMQQLGV----VSFRIRDTSMEEIFLRF 849
                        ..||:.:.||    ..|.|:..|:.:.....|    |...:|.   |:|.|
E. coli   257 ------------EGVLKERQEDGLVLDSPGLVHPLKVDADASVVDNVPVHVALRP---EKIML-- 304

  Fly   850 GCEDNDQSGAFQSHENAQVLLEEYYSTLAEANEKGRRTGWKLFFLHGRAVIYKRWIAAHRH---- 910
             ||:...:|.  :....:|:...|...|:..:.:          |....:|..:...||||
E. coli   305 -CEEPPANGC--NFAVGEVIHIAYLGDLSVYHVR----------LKSGQMISAQLQNAHRHRKGL 356

  Fly   911 --W---IVLIFEVLAMALVAV 926
              |   :.|.:||.:..::.|
E. coli   357 PTWGDEVRLCWEVDSCVVLTV 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468
		CcmA	541..848	CDD:224054	76/322 (24%)
		ABC_subfamily_A	541..761	CDD:213230	58/227 (26%)
		ABC2_membrane_3	911..>1189	CDD:289468	5/19 (26%)
		ABC2_membrane	<1080..>1188	CDD:304374
		ABC_subfamily_A	1370..1577	CDD:213230
		PRK14255	1371..1586	CDD:172743
potG	NP_415376.4	potG	1..377	CDD:183226	93/409 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14986
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	2	2.000