DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1494 and ABCA12

DIOPT Version :9

Sequence 1:	NP_001259763.1	Gene:	CG1494 / 33102	FlyBaseID:	FBgn0031169	Length:	1695	Species:	Drosophila melanogaster
Sequence 2:	NP_001318859.1	Gene:	ABCA12 / 836292	AraportID:	AT5G61700	Length:	917	Species:	Arabidopsis thaliana

Alignment Length:	787	Identity:	168/787 - (21%)
Similarity:	313/787 - (39%)	Gaps:	176/787 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 GLCF--DGSPFVEDQVFEEDTLESYSNIQPMLNYTILLPSELRMLD-GDFRMANWM-TLYNDDPN 205
            |||.  :.|..|.|::|:    .|:......:...|:...:|...| .:|.:..|. :.|||:..
plant   212 GLCLWRNNSVEVNDELFK----GSWRGNPAGMPNEIVAAYDLMSTDRKNFNVTIWYNSTYNDEFA 272

  Fly   206 T---FVLTRLNQPYEGGFVGYVREGFIRLQKS----VSESFLVLTSHKSLPTIQIRRFPITGREQ 263
            |   ..|.|:.:.     :..:...:::..|.    :...||     |.:|..:      |...|
plant   273 TGQALKLVRVPRS-----INLISNAYLKFLKGPGTRILFEFL-----KEVPKEE------TKMNQ 321

  Fly   264 D--PLMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIY 326
            |  .|:|.|.    |..::..|||  :.:..:|.|||.::|   |.|.:..|.....|.:....:
plant   322 DIASLLGPLF----FTWVVLLLFP--VILTSLVYEKQERLR---IIMKMHGLGDGPYWMISYAYF 377

  Fly   327 EMISSLIIAAL--------LKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNAL 383
            ..||.|.:.:|        ||.....|:.:  |..:|      |.|:...::.|.:|::.|
plant   378 LTISMLYVISLVGFGSAIGLKYFRRNDYSI--QFVFY------FIYSNLQISLAFLVSSIF---- 430

  Fly   384 NAVRVLTIL-WIMSY----VPTFILSNNLEGNIHALRYVSYALPNVVATLVIEFLIERE-----S 438
            :.|:.:|:: :|:.|    :.:|:....:|         :.:.|.       |:::..|     |
plant   431 SKVKTVTVIAYILVYGTGLLGSFLFQKMIE---------TQSFPE-------EWILAMELYPGFS 479

  Fly   439 IVHITWEDSGYRLNYDG-----------GHI-TVTASSWIFMLNALVYCAIGLYVDMWRGGDRSG 491
            :....:|.|.|....:|           |.: .:.:..|...|      .:..|:|.   ...||
plant   480 LYRGLYEFSQYASRGNGMKWQDLSDSGMGEVFCIMSVEWFLAL------IVAYYIDQ---VFTSG 535

  Fly   492 KK--------MKKPNTNASVQEDPYHERGDS-----------FTHQGQAIGVNSTKI-YEVEPSH 536
            |.        .|.|   :|:...|..:|.||           .|.:.:::    .|: .|....|
plant   536 KHPFFFLVNLFKSP---SSLPRRPTVQRLDSKRVFIDMDKHDVTQERESV----QKLRNEGSTGH 593

  Fly   537 RRFKLKIKKLCK-RFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVM 600
            ......:||:.. |.....:.|:.....:|...|...::|.||.||::.:.::.||::||.||.:
plant   594 AILCDNLKKVYPGRDGNPPKMAVRGLYLSVSSGECFGMLGPNGAGKTSFISMMTGLLKPSSGTAL 658

  Fly   601 ISSHNIQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNN-----IE--------ID 652
            :...:|..:.......:|:...||:|....|..::|.|..|:|.:..:     :|        .|
plant   659 VQGLDICKDMNKVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNIKGSDLTQAVEESLKSVSLYD 723

  Fly   653 G------QSNYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQS 711
            |      ..||      .||:|.:            :|:..:.:||..::.:|:..:.||..::.
plant   724 GGVGDKPAGNY------SGGMKRR------------LSVAISLIGNPKVVYLDEPSTGLDPASRK 770

  Fly   712 LVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCVKGK 776
            .:||:|...|....|||.::|...||.:.||:.|..:|.|:|.|....||:.||..|..|.....
plant   771 NLWNVIKRAKQNTAIILTTHSMEEAEFLCDRLGIFVDGGLQCIGNSKELKSRYGGSYVFTMTTSS 835

  Fly   777 NYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENMQQLGVVSFRIRDTS 841
            .:: :|:..::.|..||......:.....|.|. |.|.:...:...:|:......|.::.:.||:
plant   836 KHE-EEVERLVESVSPNAKKIYHLAGTQKFELP-KQEVRIAEVFRAVEKAKANFTVFAWGLADTT 898

  Fly   842 MEEIFLR 848
            :|::|::
plant   899 LEDVFIK 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	49/248 (20%)
		CcmA	541..848	CDD:224054	78/326 (24%)
		ABC_subfamily_A	541..761	CDD:213230	58/239 (24%)
		ABC2_membrane_3	911..>1189	CDD:289468
		ABC2_membrane	<1080..>1188	CDD:304374
		ABC_subfamily_A	1370..1577	CDD:213230
		PRK14255	1371..1586	CDD:172743
ABCA12	NP_001318859.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810