Protein Alignment CG1494 and abca8

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: XP_031749971.1
• Gene: abca8 / 549630
• XenbaseID: XB-GENE-1005441
• Length: 1619
• Species: Xenopus tropicalis
• Alignment Length: 1615
• Identity: 349/1615 - (21%)
• Similarity: 669/1615 - (41%)
• Gaps: 312/1615 - (19%)

  Fly   220 FVGYVREG-------------FIRLQKSVSESFLVLTSHKSL-----PTIQIR-RFPITGREQDP 265
            |:|:...|             |:.||.|:..:.:.|||:.|:     ..:.:| :..:....|..
 Frog   157 FMGFCAPGSQACYPTYYWSRQFLSLQASIDSAIIELTSNHSVWDNMASVVTVRMKSTVASFRQYF 221

  Fly   266 LMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIYEMIS 330
            .:|...:.|| :..:..::...|:    ::.::.::|:.|..|.:.:|..::||.|..|.|.:|.
 Frog   222 HIGTFIFLMP-MCYVSLMYLLSLY----ITRERREMRELLKMMRLKDLAFWLSWGLLYLFYILIL 281

  Fly   331 SLIIAALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRN-ALNAVRVLTILWI 394
            :.::..:.|.      .|..|:.:.|::.:...|..|.::|..|::|.||: ...|:....|...
 Frog   282 ANLMTLVTKA------FVFVQSSYGIIMFLFVFYGIALMSFTFMLSALFRSPRATAIAGFFITLF 340

  Fly   395 MSYVPTFILSNNLEGNIHALRYVSYALPNVVATLV-----IEFLIERESIVHITWEDSGYRLNYD 454
            :|.:...:|..:              .|..:|.|:     ..|.:.....||:..:..|...:..
 Frog   341 LSALGLVLLRKD--------------FPQALAVLLSIFPQFAFAVGLTESVHMESDLQGVYFSDM 391

  Fly   455 GGHITVTASSWIFM-LNALVYCAIGLYVDMWRGGDRSGKK------------MKKPNTNASVQED 506
            .|..:...||:|.: |:::.|..:.||.:... .|:.|.|            .||..:....|.:
 Frog   392 AGDSSHVLSSFISLALDSIFYMGLTLYFEKVL-ADKHGLKYEPFFFMKSSYWSKKKLSPVLTQTE 455

  Fly   507 PYHERGDSFTHQGQAIGVNSTKIYEVEP--SHRRFKLKIKKLCKRFATNDR--PALNLFSWNVYE 567
               :.|:|      ::|    :.:|..|  .|.:..::|.|:.|::...|:  .||.....|:||
 Frog   456 ---DSGES------SMG----EFFERVPIDLHGKEAIRINKVMKKYCDQDKNIEALRGLDLNIYE 507

  Fly   568 NEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASME--LGIAFGHDMLLTGF 630
            .::|.|:||:|.||:|||.||:||...|.|:..:.|:.:...:....::  .|.....|:.....
 Frog   508 GQITALLGHSGAGKTTLLNILSGLCPASDGSATVYSYKLSDMQHLEEIKKRTGFCPQSDVKFNPL 572

  Fly   631 TVIDYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPI 695
            ||.:.|....::||:... :|..:....|:.||:..::......|:......:::..|.:|:..:
 Frog   573 TVKENLTVFAKIKGIPRK-QIKHKVQKVLSDLQMNDIENVEADNLSGGQRRKLTLGIALLGDPQV 636

  Fly   696 ILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFL 760
            :|:|:..:.||..::..:|.::.|.|:.|..:..:.....|:.:|||.|::|||.|||.|:..||
 Frog   637 LLLDEPTAGLDPCSRHHIWTILKENKADRVTLFSTQFMDEADILADRKAVISNGRLKCVGSSLFL 701

  Fly   761 KNMYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEE 825
            |..:|.||.|..........:.:..::..::|:..:......::|:.|..:..|.||.|...|:
 Frog   702 KRKWGIGYHLRMQVSPTCDVELMTSIIKQHVPDAKLTAQNEEELTYTLPFENMDAFPDLFLHLD- 765

  Fly   826 NMQQLG--VVSFRIRDTSMEEIFLRFGCED----------NDQSGAFQSHENAQVLLEEYYSTLA 878
              .|:|  :|::.:..|:::::||:...|.          :..|||.:..:.....:|:   :|.
 Frog   766 --GQVGNSIVNYGVSMTTLDDVFLKLEGEGEIEKGDYGVFSPDSGAPEDKDCFSAGMED---SLL 825

  Fly   879 EANEKGRRTGWKLFFLHGRAVIYKRWIAAHR-------------HWIVLIFEVLAMALVAVCTFS 930
            ..::.|..|      |.|.::..::.:|..|             ..|:::..:..:.::......
 Frog   826 LMSDSGSAT------LSGLSLWRQQVLAIARVRLLKLKHDSKTFRSILILLALFIIPIIMTTIVI 884

  Fly   931 SIFIYGKNYELEPLTFNLSQLHTVDAFVELFSEEEDVKDMHAYYTELLYWYDAHVATLTKNRHNA 995
            .||.....:||.|..:              |...||  ..|.|||:|..:.:    |.:......
 Frog   885 KIFHKVITWELTPSLY--------------FQHPED--RFHRYYTDLQIYNN----TGSSIEDFL 929

  Fly   996 YALLTQNQFTAHVNSRYIFGATFDQKIV-----------TAWFNNIPLHSAPYALNVVHNAVARH 1049
            .||..||.....||..|....||.:..:           |...|....::.|..:|::.||:..
 Frog   930 GALKEQNIAVQVVNGEYDMETTFYRGAIEVSQATKGYGFTIVGNPKAQNALPVLVNIISNALLM- 993

  Fly  1050 LFDEEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVLTFIWPAFAIYMITERGSLLKKQ 1114
            :|:....|.|...|:. ...:..|  .|.||..  .|.:....:.:.|.||:..|.:|....:.|
 Frog   994 IFNSTEHIRVWNHPVT-EYLVEDF--ESVTFYS--GFMLLLFASGLAPHFAMSSIEDRRIKARTQ 1053

  Fly  1115 QFLAGVRVCSYWTFTVLYD--LLFLLIFCACVVVMVALYENPNHDVMLYGYISVTLMLG----GF 1173
            ..::|:...:||....|.|  |.::|:|     :|||:..:.|..|:.....::.|:.|    |.
 Frog  1054 LRISGIFPSAYWFGQALVDVPLYWILLF-----LMVAILFSFNSQVIFSFVPAIILITGVIGYGA 1113

  Fly  1174 WVILLAYLMASLCRNPCYGFLWLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLF 1238
            .|:|..|:::         |::..|             ::|.:...:                .|
 Frog  1114 AVVLYVYVIS---------FVFGRG-------------KSHHDGWSI----------------FF 1140

  Fly  1239 MIYEF-KLICMDPV----VNFTSVEVFKCNSIPNC--CIKSNYGTFTAGIYH-------DLVILT 1289
            :|..| .:|.:|.|    |..|...:...:::...  ||         .:||       |..:|.
 Frog  1141 VISAFIPMILLDVVSTYAVGITFFLLLPASTLSGIIRCI---------DVYHFDRSTLEDEHLLY 1196

  Fly  1290 L----LDIILLA-CLFVSEYHSILGFADCRLDTRTNESPDSNQESRAFPGILSNDTAALVDKEHT 1349
            |    |.|::.: .|:|.|  .:.|....:.:....:....|||.      |..||    |:|
 Frog  1197 LFFPFLHIVIFSVILWVLE--RVFGMRSLKTNLFYRKKVQKNQEE------LGEDT----DEE-- 1247

  Fly  1350 SRLNEEERSKYAAVGIGIVSK--------------------YRRNR--VLRDLDFTLAKSECLSI 1392
             .|.|.||.|.::....:..|                    :::|:  ..:::.|.:.|.|.|.:
 Frog  1248 -VLAERERVKMSSTTNNMEEKPIIIVDSLRKEYKVKKGKSFFKKNKKAATKNISFCVRKGEVLGL 1311

  Fly  1393 TGANNSGKTTLLKVVVNETKMNAGQLWI----HDYSVNTHRVQCYRMVGYCPQKDSLPSEFTPRE 1453
            .|.|.:||||.:.::..|.:..||::.:    .|.|.|: :......:|||||.:.|....|.::
 Frog  1312 LGPNGAGKTTSIYMLAGEIRPTAGEVLLCGTDPDKSQNS-QYDPTGSLGYCPQDNPLWPNLTVKQ 1375

  Fly  1454 LLYIHAMLQGHRHRIG----RELSEALLRLVGLTPCWNRSVRMCTTGQIRRLYFAYAVLGSPDLI 1514
            .|.|:|.::|.:.:..    :.:||||    .|.....::.|..:.|..|::.||.::||:|:::
 Frog  1376 HLEIYAAVKGLKKKDAETAIKRVSEAL----ELKEHLEKAARKLSAGVSRKVCFAISMLGNPNIV 1436

  Fly  1515 CVDGVPAGLDPTG-KRIILMMTSTMQAMGSSFLYTMLTGLDAERLSLRTPLLLEGQLWMIRPMDT 1578
            .:|....||||.| :|:...:.|..:......:.|.....:||.:..|..:::.|:|..|..:..
 Frog  1437 LLDEPSTGLDPKGQQRLWRAIRSAFRNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQ 1501

  Fly  1579 ETENYKSGYQLEVRFKRKVNPNVSMSRATWNLINHFPMSPNK-KFSAFMEIKFPDAVLTIERDDS 1642
            ....:..||.||::.|   |.| .:.:....:|..||.:..: :||:.:..|.|     :|...|
 Frog  1502 LKSKFGKGYLLEIKVK---NSN-QVDQIHNEIIQIFPHAARQDRFSSLLVYKIP-----VENVQS 1557

  Fly  1643 MVFVLPLGTTTFSEIFLTLRKDAFEMNIEDYFITRNMLVGFQIF---TYDQHQDN 1694
            :           |:.||.|.:.....|||:|..::..|.  |:|   |.:|.:::
 Frog  1558 L-----------SKAFLDLEEAKRAYNIEEYSFSQPTLT--QVFIELTKEQERED 1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	43/223 (19%)
		CcmA	541..848	CDD:224054	80/312 (26%)
		ABC_subfamily_A	541..761	CDD:213230	61/223 (27%)
		ABC2_membrane_3	911..>1189	CDD:289468	64/294 (22%)
		ABC2_membrane	<1080..>1188	CDD:304374	27/113 (24%)
		ABC_subfamily_A	1370..1577	CDD:213230	57/237 (24%)
		PRK14255	1371..1586	CDD:172743	56/225 (25%)
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	335/1547 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010