Protein Alignment CG1494 and CG8908

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: NP_611464.3
• Gene: CG8908 / 37293
• FlyBaseID: FBgn0034493
• Length: 1626
• Species: Drosophila melanogaster
• Alignment Length: 1808
• Identity: 392/1808 - (21%)
• Similarity: 715/1808 - (39%)
• Gaps: 335/1808 - (18%)

  Fly    16 KNHKLQLANPLELLVILLVPPLFTLVAVLMRFFIPVNHRSDTVYDPIDLDRSWMQMVEKLEKARQ 80
            |..:.|.:|.|..::|::.|.:..||......|......:...|.|:::
  Fly    23 KTARFQFSNTLTSVIIIVGPIVVFLVYAATALFREPQEETSVKYPPVNI---------------- 71

  Fly    81 VADTYNVKGNPFTPHLVIGWAPKRYGIFQAMMRRVQKQIEPMTSVGFEDCEEMRESVIENGL--F 143
               |..|   |:     |.::|:.. :..|::..|...::.:.|..|....|:.:::|....  :
  Fly    72 ---TTKV---PY-----IYYSPENL-VLAAVIEDVVHDLKAVGSKAFASASELNKALIGKDTYGY 124

  Fly   144 AGLCFDGSPFVEDQVFEEDTLESYSNIQPM-LNYTILL--PSELRMLDGDFRMANWMTLYNDDPN 205
            .|:.||               :|:|:|..: :|.|:.|  |..||.   :.:|. |       .|
  Fly   125 VGIEFD---------------DSFSDINELPINVTVGLRFPLHLRK---NPKMV-W-------DN 163

  Fly   206 TFVL--TRLNQPYEGGFVGYVREGFIRLQKSVSESFLVLTSHKS--LPTIQIRRFPITGREQDPL 266
            |.:|  ::::..|      |..|||:.:|..:||: |:...:::  ||.:.::.:|... |.|.|
  Fly   164 TSILKHSKMDVDY------YQVEGFLVVQAKLSEA-LIRAKNEAVVLPEVILQHYPDVA-EVDRL 220

  Fly   267 MGNLNYG----MPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIYE 327
            ...:..|    :|..|...:|  ||:    :|.|::..:|..|..|.:...|:::||:|...:..
  Fly   221 DNRVALGGVLFLPVTISAAYL--AQM----IVMERRDHLRDMLELMGVRAWIYWLSWFLVAFLLL 279

  Fly   328 MISSLIIAALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNALNAVRVLTIL 392
            .|.::.:..|||.|:      .:.:...:::..|..||...:..|.|:::||.:.:.....:.|:
  Fly   280 SIPTVFMVLLLKWRY------FSLSDSSLVLFFLLVYNLEVLTSAFMISSFFSDTVGVQVAIVIV 338

  Fly   393 -------W---IMSYVPT---------------------FILSNNLEGNIHALRYVSYALPNVVA 426
                   |   :|.||||                     ||.|.||...:|
  Fly   339 HLIGCLPWRLLLMGYVPTLPRTIFVCLFLNSSLAMGLQQFIKSENLRLGLH-------------- 389

  Fly   427 TLVIEFLIER---ESIVHITWEDSGYRLNYDGGHITVTASSWIFMLNALVYCAIGLYVDMWRGGD 488
               ..:|.||   :..||:             |.|.      :|||..   |.:.:.|..:....
  Fly   390 ---WTYLFERTDWDEFVHL-------------GPIL------LFMLFG---CLLRILVLAYMEQL 429

  Fly   489 RSGKKMK-----KPNTNASVQEDPYHERGDSFTHQGQAIGVNSTKIYEVEPSHRRFKLKIKKLCK 548
            ||.:..|     :|:........|   |.|.|..:||..|:....:.          ::.:.:.|
  Fly   430 RSYQNRKWYFPVQPSFWCRWNRRP---RSDDFDVEGQETGIRGHPLI----------VRARNIEK 481

  Fly   549 RFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAA 613
            .|  |:..|:...:.|.|::|:||.:|||..||||:|.:|||.:.||.|.:.|:.:::.|.::.|
  Fly   482 VF--NEWIAVKDLNLNFYQDEITVFLGHNDSGKSTILMLLAGFLRPSAGEITINGYDLATNQRKA 544

  Fly   614 SMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDR 678
            ...:.|....::|........:|:|.||:||| |..|...:::.:|.:.::......:::.|...
  Fly   545 RQSMCICPQPNVLFEKVNARWHLQFYCRLKGL-NRQEASAETDKYLEIGRLQDFANTKVKNLPSG 608

  Fly   679 DLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRM 743
            ...::.:||...|||.|:|:|:..:.:|...:|.:|:|:..|:..|.||:.:::...||.:||::
  Fly   609 IKRMLMLCCNLCGNSKILLLDEPGTSMDPAMRSNMWDLLRRERKGRCIIMATHNMNEAEVVADQI 673

  Fly   744 AIMSNGELKCTGTKPFLKNMYGHG--YRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTF 806
            .::.:.::...||..||..:.|.|  |.|.|.|.......|:...:....|::.:..:....||:
  Fly   674 VVLCDAQVIGYGTTGFLTQIAGTGSSYLLICTKMDTCIVAEVTNFLQIRFPDIKLHNEFSIYVTY 738

  Fly   807 VLENKFEDQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIFLRFGCEDNDQS----GAFQ--SHEN 865
            .|..|:..|:..|..:|||.:.:|.:....:...::..:||:.| |:..||    .:|.  |..:
  Fly   739 ELPTKYVQQYAALFLELEEALGELNLAEISVCAPTLGSVFLQMG-EEMRQSWNRISSFDLLSSPS 802

  Fly   866 AQVLLEEYYSTLAEANEKGR---RTGWKLFFLHGRAVIYKRWIAAHRH---WIVLIFEVLAMALV 924
            ..:.|.....|.....:.||   ...|       ||::.|:.:...||   :.::|...:.:.|:
  Fly   803 PMLSLLNLLPTFEVREDDGRVKCCNQW-------RAIVEKKRLFTLRHQKFYCMIIATPIIICLL 860

  Fly   925 AVCTFSSIFIYGKNYELEPLTFNLSQLHTVDAFVELFSEEEDVKDMHAYYTELLYWYDAHVATLT 989
             :.:| ||||:..::.|..|......::....||  .....:......:|...:......|.:.:
  Fly   861 -IISF-SIFIFLVDHHLSELLVTDLSIYPKAVFV--IDSPAEGNRFERHYMANVIGQGGTVRSTS 921

  Fly   990 KNRHNAYALLTQNQFTAHVNSRYIFGATFDQKI--VTAWFNNIPLHSAPYALNVVHNAVARHLFD 1052
            ....:.|.|.........|...::.|||||...  :.||.||...|.:..::.:|:.|:.:.|
  Fly   922 GTPIDDYLLAEMESDQVKVQHTFLAGATFDSNANSIIAWSNNKLKHGSALSMGLVYAAIGQEL-- 984

  Fly  1053 EEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVLTFIW-----PAFAIYMITERGSLLK 1112
              |.:|:.:...|::..:.. ......:...:.|.   ||.|.:     ..||:..|.||.|.::
  Fly   985 --AKLDIRIVNKPYQDTVQQ-AVRGLIYASTIEFA---VLVFHYLVLGTAIFAVLPIVERRSKVQ 1043

  Fly  1113 KQQFLAGVRVCSYWTFTVLYDLLFLLIFCACVVVMVALYENPNHDVMLYGYISVTLMLGGFWVIL 1177
            .|||.:|:...:||...:.:|..|.:.....::|:..:.......|:      |.|:..||..|.
  Fly  1044 HQQFSSGMSRSTYWLSHLSWDYCFYIAMILPLIVVAGITIGSVLPVI------VQLLAFGFSAIS 1102

  Fly  1178 LAYLMASLCRNPCYGFLWLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYE 1242
            ..||:..:..:....|..:..||.||::...    .||:|         ..|...||..:.:::.
  Fly  1103 FTYLLCLMSNDFGKMFSIILYINMIGVLALF----IHPKS---------PQTRYAVIESVLLVHP 1154

  Fly  1243 FKLICMDPVVNFTSVEVFKCNSIPNCCIKSNYGTFTAGIYHDLVILTLLDIILLACLFVSEYHSI 1307
            ...:|.. :.....:..|....:|       |..|:...|        |.|::.|.
  Fly  1155 HYSLCCG-MYEAIRMSTFSLKQLP-------YLIFSGAAY--------LTIVVFAW--------- 1194

  Fly  1308 LGFADCRLDTRTNESPDSNQESRAFPGILSNDTAALVDKEHTSRLNEEERSKYAAVGI---GIVS 1369
                   :..|.|....|.:..:.:|.....|..  |||.. .||.....:.||...:   .:..
  Fly  1195 -------VPRRLNYVFKSIRNEKIYPSYKDEDKE--VDKMR-RRLAYLTTAHYAFFPLILKNLSK 1249

  Fly  1370 KYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHRVQCYR 1434
            :|.....:|.|...|...||:.:.|.|.|||:::.:::|....:..|.:.|..||:.|......|
  Fly  1250 RYGSFVAVRSLTLDLNPFECVGLLGRNGSGKSSIFRMIVGMESITVGSIHIKGYSLKTRPKDASR 1314

  Fly  1435 MVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLTPCWNRSVRMCTTGQIR 1499
            .||:||::..|.|..|.::.|....::.|.|....:.|..:|.....|.|..|:.:...:.|..|
  Fly  1315 HVGFCPRELMLLSFMTGKDALRFCCLINGIRREYIKSLVASLAECFELVPHMNKRISTYSNGTKR 1379

  Fly  1500 RLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGSSFLYTMLTGLDAERLSLRTPL 1564
            :|..|...| :|.|:|:|...||:|...|..|..:...::..|.|.|.|.....:.|.|.....:
  Fly  1380 KLMIAMGTL-APSLMCLDEPTAGVDMHAKYEIWSILDGIRQGGRSILLTTHNLEECEFLCTNVGI 1443

  Fly  1565 LLEGQLWMIRPMDTETENYKSGYQLEVRFKRKVN---------------PNVSMSRAT------- 1607
            :..|.|.....:......:..|..::|:...:..               ||.|...:|
  Fly  1444 MDHGSLLCYGSLSRLKHRFNMGIFVKVKMGTRAEMDDERDNWMQITMMPPNDSEMGSTVGARRMM 1508

  Fly  1608 -WNLINHF--PMSPNKK--------------------FSAFME-----IKFPDAVLTIERDDS-- 1642
             .:|:.|.  |:.|.||                    :.|.::     .|......|:....|
  Fly  1509 LAHLLRHHNPPVEPVKKSRTSRAQPDTTNSELNMRKDYEALLQELEEVFKKDHPYSTVSEKYSYR 1573

  Fly  1643 --MVFVLPLGTTTFSEIFLTLRKDAFEMNIEDYFITRNMLVG-FQIFTYDQHQ 1692
              :.|.:|.|...:|.||..:.....||.|..|.::...... |..|...|:|
  Fly  1574 GMITFCIPRGQIKWSAIFEYMENLKDEMQILYYSVSHTTFQDVFMKFVRKQNQ 1626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	53/254 (21%)
		CcmA	541..848	CDD:224054	82/308 (27%)
		ABC_subfamily_A	541..761	CDD:213230	62/219 (28%)
		ABC2_membrane_3	911..>1189	CDD:289468	59/284 (21%)
		ABC2_membrane	<1080..>1188	CDD:304374	27/112 (24%)
		ABC_subfamily_A	1370..1577	CDD:213230	55/206 (27%)
		PRK14255	1371..1586	CDD:172743	55/214 (26%)
CG8908	NP_611464.3	ABC2_membrane_3	69..394	CDD:289468	83/415 (20%)
		LivG	471..686	CDD:223488	59/227 (26%)
		ABC_subfamily_A	474..691	CDD:213230	62/219 (28%)
		ABC2_membrane_3	845..1192	CDD:289468	78/393 (20%)
		NatA	1242..1461	CDD:226927	55/219 (25%)
		ABC_subfamily_A	1242..1459	CDD:213230	55/217 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451231
Domainoid	1	1.000	40	1.000	Domainoid score	I3722
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm51427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	9	9.000