Protein Alignment CG1494 and Abca9

DIOPT Version :9

• Sequence 1: NP_001259763.1
• Gene: CG1494 / 33102
• FlyBaseID: FBgn0031169
• Length: 1695
• Species: Drosophila melanogaster
• Sequence 2: XP_038943368.1
• Gene: Abca9 / 287788
• RGDID: 1305931
• Length: 1653
• Species: Rattus norvegicus
• Alignment Length: 1675
• Identity: 345/1675 - (20%)
• Similarity: 647/1675 - (38%)
• Gaps: 444/1675 - (26%)

  Fly   214 QPYEGGFV----GYVREGFIRLQKSVSESFLVLTSHKSLPTIQIRRFPITGREQDPLMGNLNYGM 274
            :|::...|    .:..:||:..|.:::...:.:|::.|:.           .|...::|::....
  Rat   190 EPFKNKMVCENSVFWEKGFVAFQTAINAGIIEVTTNHSVM-----------EELMSVIGSVMKMQ 243

  Fly   275 PFIIIIG-----FLFPAQL----FVW----QVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIY 326
            |||...|     |:|...:    |::    .|..|:|| :...:..|.:.....::||   ||:|
  Rat   244 PFIAQGGVATDFFIFFCVISFSSFIYYLSVNVTQERQS-ITTLMAMMGLRESAFWLSW---GLMY 304

  Fly   327 EMISSLIIAALLK--IRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNAL---NAV 386
            ... .|::|.|:.  ::..|   |:..|.:.::.|:...|..:.:..:.:::...:...   .||
  Rat   305 AGF-ILVVATLMSLIVKSTQ---VVVLTGFMVVFLLFLLYGLSLITLSFLMSVLLKKPFLTGLAV 365

  Fly   387 RVLTILW-------IMSYVPTFILSNNLEGNIHALRYVS-YALPNVVATLVIEFLIERESIVHIT 443
            .:||:.|       :..::|.|:        ...|.::| :|..|.:|.|           :|:.
  Rat   366 FLLTVFWGSLGFTALYKHLPAFM--------EWILCFLSPFAFINGMAQL-----------IHLD 411

  Fly   444 WE-DSGYRLNYDGGHITVTASSWIFMLNALVYCAIGLYVD--------------------MW--- 484
            :: :|...||.......:.|:.::.:|:||:|.|:.||.|                    .|
  Rat   412 YDVNSNVNLNSPNNSYLILATLFMLVLDALLYLALALYFDKILLSKYGHQRSPLFFLKSSYWFQR 476

  Fly   485 RGGDR---SGKKMKKPNTNASVQEDPYHERGDSFTHQGQAIGVNSTKIYEVEPSHRRFK----LK 542
            ||.|.   ..:....|:.|.|                             :||....|:    ::
  Rat   477 RGADHVVLENEIDSAPSLNDS-----------------------------LEPVSPEFQGKEAIR 512

  Fly   543 IKKLCKRFATNDR--PALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHN 605
            ||.|.|.:.....  .||....:::||.::|.|:||:|.||:||:..|:||..|:.|::.|.:..
  Rat   513 IKNLRKEYTGKHGKVEALRGLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTTGSITIYNQT 577

  Fly   606 I-QTERKAASMEL-------GIAFGHDMLLTGFTVIDYLRFICRVKGLHNNIEIDGQSNYFLNVL 662
            : :||...|..:|       .|.||.      .||.:.||...::||:... |::.:....|..|
  Rat   578 VSETEDSYAVPKLTGVCPQSNIQFGF------LTVQENLRLFAKIKGILPQ-EVEQEVRQVLRDL 635

  Fly   663 QIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTII 727
            ::..::....:.|:......::...|.:|:..::|:|:..:.||..::..:|||:.|.:|.|.|:
  Rat   636 EMENIQDTLAQNLSGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPLSRHHIWNLLKERRSGRVIV 700

  Fly   728 LVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMP 792
            ..:.....|:.:|||...:|||.|:|.|:..|||..:|.||.|:....:....:.:..::..::|
  Rat   701 FSTQFMDEADILADRKVFISNGRLRCAGSSLFLKKKWGIGYHLSLHLNETCDPESITSLVKKHIP 765

  Fly   793 NMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIFLRF-------- 849
            :..:......::.::|..:..::||.|..|| :.....|:..:.:..|::.|:||:.
  Rat   766 DARLTAQSDEQLVYILPLERTNKFPDLYRDL-DRCSNHGIEDYDVSMTTLNEVFLKLEGKSMAEE 829

  Fly   850 ------------GCED------------NDQSGAFQSHENAQVLLEEYYSTLAEA------NEKG 884
                        |.:|            .|.||   |..:...|..:....:|:.      ||
  Rat   830 PDAGVCGRLLSDGAKDVESLVELERVLPLDSSG---SSVSGMALWRQQLCAVAKVRFLKLKNE-- 889

  Fly   885 RRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFEVLAMALVAVCTFSSIFIYGKNYE--LEPLTFN 947
            ||:...:..|.|  :.:...:..|     |:::|                |.|:|.  |.|..:.
  Rat   890 RRSLMTMLLLFG--ISFVPQLLEH-----LVYKV----------------YHKSYSWGLSPSMYF 931

  Fly   948 LS--QL---------------HTVDAFVELFSEEEDVKDMHAYYT-----ELLYWYDAHVATLTK 990
            ||  ||               .::|.|:....::....|:.|..|     |.||
  Rat   932 LSPGQLPQDPLTHLLVINKTGSSIDNFIHSLRQQGIALDVDALGTRNGKEEALY----------- 985

  Fly   991 NRHNAYALLTQN---QFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVARHLFD 1052
              :.|..:|...   :|:...|::                   .|:..|...:::.|.:. .:|:
  Rat   986 --NGAVTVLGDEKDLRFSVACNAK-------------------RLNCFPVLADILSNGLL-GIFN 1028

  Fly  1053 EEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVL-TFIW--------PAFAIYMITERG 1108
            ....|..               ..|..|...:.:...|:. .|.|        |..|:..|::..
  Rat  1029 SSERIQT---------------DRSTVFEDHMLYEYGFMSNAFFWIPVAASLTPYIAMGSISDHK 1078

  Fly  1109 SLLKKQQFLAGVRVCSYWTFTVLYDLLFLLIFCACVVVMVALYENPNHDVM------------LY 1161
            ..:..|.:.:|:...:||....|.|:....:....:.:|.:::.  :.::|            ..
  Rat  1079 KKVLSQLWTSGLYPSAYWCGQALVDIPIYFLILLLMQIMDSVFS--SEEIMSVIESLLIQIPCSI 1141

  Fly  1162 GYISVTLML--------------GGFW-----VILLAYLMASLCRNPCYGFLWLCGINSIGLVCF 1207
            ||.|..:.|              .|.|     ::.:.:::|:....  ||||.|       |.|
  Rat  1142 GYASSLIFLTYVISFVFRNGRKNSGIWSFFFLIVTIFFIVATDINE--YGFLQL-------LFC- 1196

  Fly  1208 SQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYEFKLICMDPVVNFTSVEVFKCNSIPNCCIKS 1272
                      .||.|.|       |:|..|.:..|.....:|.:.:..|..||....||
  Rat  1197 ----------TLLIPPF-------TLIGSLLIFSEVSYDSVDYLGSSESQLVFLALLIP------ 1238

  Fly  1273 NYGTFTAGIYHDLVILTLLDIILLACLFVSEYHSILGFADCRLDTRTNESPDSNQESRAF----- 1332
             |..|            ||...:|.||     ...:.....|:|.....||.|   .|||
  Rat  1239 -YLHF------------LLFFFILRCL-----ERYIRKKTLRVDPVFRISPRS---CRAFPNPED 1282

  Fly  1333 PGILSNDTAALVDKEHTS------RLNEEE-------RSKYAAVGIGIVSKYRRNRVLRDLDFTL 1384
            ||  ..|....:::..||      :::|:.       |.:|........||.::....|::.|.:
  Rat  1283 PG--EEDEDVQMERVRTSGAMTTPQMDEKPVIIASCLRKEYTVKTKRCFSKTKKKIATRNISFCV 1345

  Fly  1385 AKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHRVQCYRMVGYCPQKDSLPSEF 1449
            .|.|.|.:.|.|.:||:|.:.::..:|...|||:::...|.:.    ....:|||||::.|....
  Rat  1346 KKGEVLGLLGHNGAGKSTTISMITGDTVPTAGQVFLKGSSGSA----ALGFLGYCPQENVLWPNL 1406

  Fly  1450 TPRELLYIHAMLQGHRHRIGRELSEALLRLVG---LTPCWNRSVRMCTTGQIRRLYFAYAVLGSP 1511
            |.:|.|.::|.::|.|.   :|....:.|||.   |.......|:..:.|..|:|.|..::||:|
  Rat  1407 TVKEHLEVYAAVKGLRK---KEAIVTITRLVNALKLQDQLKALVKTLSEGVKRKLCFVLSILGNP 1468

  Fly  1512 DLICVDGVPAGLDPTGKRIILMMTSTMQAMGSSFLYT----MLTG---LDAERLSLRTPLLLEGQ 1569
            .::.:|....|:||.|::      ...||:.::|..|    :||.   .:||.:..|..:::.|:
  Rat  1469 SVVLLDEPSTGMDPEGQQ------QMWQAIRATFTNTERGALLTTHYMAEAEAVCDRVAIMVSGR 1527

  Fly  1570 LWMIRPMDTETENYKSGYQLEVRFKRKVNPNVSMSRATWNLINHFPMSP-NKKFSAFMEIKFP-- 1631
            |..|..:......:...|.||::.|   .|.:..|..| .::..||.:. .:::|:.|..|.|
  Rat  1528 LRCIGSIQHLKSKFGKDYLLEMKLK---TPALVESLNT-EILRLFPQAARQERYSSLMVYKLPVE 1588

  Fly  1632 ------DAVLTIER--DDSMVFVLPLGTTTFSEIFLTLRKDAFEMNIEDY 1673
                  :|...:||  ::..:....|..:|..::||.|.|   |..:.|:
  Rat  1589 DVRPLSEAFFKLERLKENFDLEEYSLSQSTLEQVFLELSK---EQELGDF 1635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1494	NP_001259763.1	ABC2_membrane_3	<263..480	CDD:289468	49/243 (20%)
		CcmA	541..848	CDD:224054	81/316 (26%)
		ABC_subfamily_A	541..761	CDD:213230	64/229 (28%)
		ABC2_membrane_3	911..>1189	CDD:289468	51/344 (15%)
		ABC2_membrane	<1080..>1188	CDD:304374	22/147 (15%)
		ABC_subfamily_A	1370..1577	CDD:213230	58/216 (27%)
		PRK14255	1371..1586	CDD:172743	57/224 (25%)
Abca9	XP_038943368.1	rim_protein	<207..1630	CDD:130324	341/1651 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850